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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2022-11-1-49-55</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1054</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Кардиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiology</subject></subj-group></article-categories><title-group><article-title>Табакокурение и состояние когнитивных функций у подростков: популяционное исследование</article-title><trans-title-group xml:lang="en"><trans-title>Tobacco smoking and cognitive functionioning in adolescents: a population study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1407-269X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суханов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhanov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Суханов Андрей Владимирович - кандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний.</p><p>ул. Б. Богаткова, 175/1, Новосибирск, 630089.</p></bio><bio xml:lang="en"><p>Andrey V. Sukhanov - PhD, Senior Researcher at the Laboratory of Psychological and Sociological Problems of Therapeutic Diseases, Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences.</p><p>175/1, B. Bogatkova St., Novosibirsk, 630089.</p></bio><email xlink:type="simple">25081973@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2470-2133</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисова</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisova</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Денисова Диана Вахтанговна - доктор медицинских наук, главный научный сотрудник лаборатории профилактической медицины.</p><p>ул. Б. Богаткова, 175/1, Новосибирск, 630089.</p></bio><bio xml:lang="en"><p>Diana V. Denisova - PhD, Leading Researcher at the Laboratory of Preventive Medicine, Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences.</p><p>175/1, B. Bogatkova St., Novosibirsk, 630089.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2168-9911</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пилипенко</surname><given-names>П. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pylypenko</surname><given-names>P. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пилипенко Павел Иванович - доктор медицинских наук, профессор заведующий кафедрой клинической неврологии и нейрогериатрии.</p><p>Красный проспект, 52, Новосибирск, 630091.</p></bio><bio xml:lang="en"><p>Pavel I. Pilipenko - PhD, Professor, Head of the Department of Clinical Neurology and Neurogeriatrics, Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” of Ministry of Healthcare of the Russian Federation.</p><p>52, Krasny Ave., Novosibirsk, 630091.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5701-7856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гафаров Валерий Васильевич - доктор медицинских наук, профессор заведующий лабораторией психологических и социологических проблем терапевтических заболеваний.</p><p>ул. Б. Богаткова, 175/1, Новосибирск, 630089.</p></bio><bio xml:lang="en"><p>Valery V. Gafarov - PhD, Professor, Head of the Laboratory of Psychological and Sociological Problems of Therapeutic Diseases, Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences.</p><p>175/1, B. Bogatkova St., Novosibirsk, 630089.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт терапии и профилактической медицины - филиал федерального государственного бюджетного научного учреждения «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук»<country>Россия</country></aff><aff xml:lang="en">Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Новосибирский государственный медицинский университет Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Novosibirsk State Medical University of the Ministry of Healthcare of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>25</day><month>03</month><year>2022</year></pub-date><volume>11</volume><issue>1</issue><fpage>49</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Суханов А.В., Денисова Д.В., Пилипенко П.И., Гафаров В.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Суханов А.В., Денисова Д.В., Пилипенко П.И., Гафаров В.В.</copyright-holder><copyright-holder xml:lang="en">Sukhanov A.V., Denisova D.V., Pylypenko P.I., Gafarov V.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1054">https://www.nii-kpssz.com/jour/article/view/1054</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения. При популяционном исследовании репрезентативной выборки подростков Сибири впервые выявлены количественные изменения паттернов памяти и внимания, ассоциированные с курением, в зависимости от пола. У курящих на момент обследования подростков среднее количество допущенных ошибок в тесте с запоминанием 10 слов было выше по сравнению с некурящими.</p></sec><sec><title>Актуальность</title><p>Актуальность. Данные литературы об ассоциации когнитивных нарушений со статусом курения, являющимся конвенционным фактором риска сердечно-сосудистых заболеваний, в подростковом возрасте в условиях открытой популяции до настоящего времени остаются противоречивыми.</p></sec><sec><title>Цель</title><p>Цель. Оценить влияние курения на отдельные показатели когнитивных функций (КФ) у подростков в условиях открытой популяции Новосибирской области.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. КФ исследованы у 549 подростков (231 мальчика (42,1%) и 318 девочек (57,9%), средний возраст 15,66±0,9 года), из них анкету о курении заполнили 332 участника. КФ оценивали с помощью корректурной пробы, теста Лурия с запоминанием 10 слов и теста исключения понятий. Статус курения определяли на основании анкетного опроса. Регулярным курильщиком считали подростка, выкуривавшего не менее одной сигареты в неделю.</p></sec><sec><title>Результаты</title><p>Результаты. У курящих на момент обследования подростков (n = 67) среднее количество допущенных ошибок в тесте с запоминанием 10 слов было выше по сравнению с некурящими (n = 265): 2,21±1,04 против 1,88±1,05 слова. При этом между курящими и некурящими подростками мужского пола статистически значимых отличий по этому показателю не выявлено, в то время как различия между курящими и некурящими девочками-подростками сохранялись.</p></sec><sec><title>Заключение</title><p>Заключение. У курящих подростков преимущественно страдает непосредственное запоминание предъявленного стимульного материала. Это связано с худшим усвоением подростками-курильщиками обучающих материалов в школе.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights. A population-based study of a representative sample of Siberian adolescents revealed for the first time quantitative changes in memory and attention patterns associated with smoking, depending on gender. At the time of the survey of adolescents, the average number of mistakes made in the test with memorization of 10 words was higher in comparison with non-smokers.</p></sec><sec><title>Background</title><p>Background. The literature data on the association of cognitive impairment with smoking status, which is a conventional risk factor for cardiovascular diseases, in adolescence in an open population remains controversial.</p></sec><sec><title>Aim</title><p>Aim. To examine the effect of smoking on certain cognitive functions indicators in adolescents in the open population of the Novosibirsk region.</p></sec><sec><title>Methods</title><p>Methods. Cognitive functions were studied in 549 adolescents (231 boys (42.1%) and 318 girls (57.9%), mean age - 15.66±0.9 years). The smoking questionnaire in this group was completed by 332 participants. Cognitive functions were assessed using a proofreading test, a Luria test with memorization of 10 words, and a concept exclusion test. Smoking was assessed based on a questionnaire survey. An adolescent, who smoked at least 1 cigarette per week was considered a regular smoker. Descriptive statistics methods and analysis of contingency tables were performed in the statistical package “R” for Windows.</p></sec><sec><title>Results</title><p>Results. Among adolescents who smoked at the time of the examination (n = 67), the average number of mistakes in the test with memorization of 10 words was higher (2.21±1.04 words), compared with 1.88±1.05 words in the non-smoking group (n = 265). At the same time, there were no statistically significant differences in this cognitive indicator between male smokers and nonsmokers, while differences between female smokers and nonsmokers remained.</p></sec><sec><title>Conclusion</title><p>Conclusion. In adolescents who smoke, direct memorization of the presented stimulus material is predominantly affected. This is due to the worst assimilation of educational materials by adolescent smokers.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Когнитивные функции</kwd><kwd>Курение</kwd><kwd>Подростки</kwd><kwd>Популяция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Cognitive functions</kwd><kwd>Smoking</kwd><kwd>Adolescents</kwd><kwd>Population</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Работа выполнена в рамках бюджетной темы по государственному заданию ААА-А-А17-117112850280-2 и при финансовой поддержке гранта РФФИ 19-013-00800 «Многолетняя динамика избыточной массы тела среди молодых россиян: оценка вклада генетических, поведенческих и социально-экономических факторов в рост распространенности ожирения в России».</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кутбаев М.А. 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