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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">kpccz-1215</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОНЛАЙН. АНАЛИТИЧЕСКИЙ ОБЗОР. Неврология. Лучевая диагностика</subject></subj-group></article-categories><title-group><article-title>ВИЗУАЛИЗАЦИЯ НЕЙРОПЛАСТИЧНОСТИ ГОЛОВНОГО МОЗГА В АСПЕКТЕ ПОСТИНСУЛЬТНОЙ РЕАБИЛИТАЦИИ</article-title><trans-title-group xml:lang="en"><trans-title>VISUALIZATION OF BRAIN NEUROPLASTICITY IN THE ASPECT OF POST-STROKE REHABILITATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7959-5160</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Станкевич</surname><given-names>Юлия Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Stankevich</surname><given-names>Yuliya A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук заведующая лабораторией функциональной нейровизуализации, старший научный сотрудник федерального государственного бюджетного учреждения науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация; старший преподаватель центра постдипломного медицинского образования института медицины и медицинских технологий федерального государственного автономного образовательного учреждения высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, MD, Head of the Laboratory of Functional Neuroimaging, Senior Researcher, Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation; Senior Lecturer at the Center for Postgraduate Medical Education, Institute of Medicine and Medical Technologies, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk State University”, Novosibirsk, Russian Federation</p></bio><email xlink:type="simple">stankevich@tomo.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3082-2315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>Владимир Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>Vladimir V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник федерального государственного бюджетного учреждения науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация; ординатор 2-го года центра постдипломного медицинского образования института медицины и медицинских технологий федерального государственного автономного образовательного учреждения высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск, Российская Федерация</p></bio><bio xml:lang="en"><p>MD, Junior Researcher at the Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation; 2nd year Resident at the Center for Postgraduate Medical Education, Institute of Medicine and Medical Technologies, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk State University”, Novosibirsk, Russian Federation</p></bio><email xlink:type="simple">v.popov1@g.nsu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8880-100X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богомякова</surname><given-names>Ольга Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Bogomyakova</surname><given-names>Olga B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук научный сотрудник федерального государственного бюджетного учреждения науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация; старший преподаватель центра постдипломного медицинского образования института медицины и медицинских технологий федерального государственного автономного образовательного учреждения высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, MD, Researcher at the Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation; Senior Lecturer at the Center for Postgraduate Medical Education, Institute of Medicine and Medical Technologies, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk State University”, Novosibirsk, Russian Federation</p></bio><email xlink:type="simple">bogom_o@tomo.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1838-8130</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Василькив</surname><given-names>Любовь Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilkiv</surname><given-names>Lyubov M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук старший научный сотрудник федерального государственного бюджетного учреждения науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация; старший преподаватель центра постдипломного медицинского образования института медицины и медицинских технологий федерального государственного автономного образовательного учреждения высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, MD, Researcher at the Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation; Senior Lecturer at the Center for Postgraduate Medical Education, Institute of Medicine and Medical Technologies, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk State University”, Novosibirsk, Russian Federation</p></bio><email xlink:type="simple">vasilkiv@tomo.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1277-4113</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тулупов</surname><given-names>Андрей Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Tulupov</surname><given-names>Andrey A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, член-корреспондент РАН главный научный сотрудник федерального государственного бюджетного учреждения науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук, главный ученый секретарь Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация; заместитель директора, профессор центра постдипломного медицинского образования института медицины и медицинских технологий федерального государственного автономного образовательного учреждения высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, MD, Professor, Corresponding Member of the Russian Academy of Sciences, Head of the Laboratory of Neurosciences, Chief Researcher at the Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation; Deputy Director, Professor at the Center for Postgraduate Medical Education, Institute of Medicine and Medical Technologies, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk State University”, Novosibirsk, Russian Federation</p></bio><email xlink:type="simple">taa@tomo.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6990-2158</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сагдеев</surname><given-names>Ренад Зиннурович</given-names></name><name name-style="western" xml:lang="en"><surname>Sagdeev</surname><given-names>Renad Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор химических наук, профессор, академик РАН научный руководитель федерального государственного бюджетного учреждения науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, Academician of the Russian Academy of Sciences, Scientific Head of the Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russian Federation</p></bio><email xlink:type="simple">itc@tomo.nsc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук; &#13;
Федеральное государственное автономное образовательное учреждение высшего образования «Новосибирский национальный исследовательский государственный университет»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences; &#13;
Federal State Autonomous Educational Institution of Higher Education “Novosibirsk State University”<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение науки Институт «Международный томографический центр» Сибирского отделения Российской академии наук<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution of Science “International Tomography Center” of Siberian Branch of Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>11</day><month>01</month><year>2025</year></pub-date><volume>13</volume><issue>4</issue><fpage>214</fpage><lpage>228</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Станкевич Ю.А., Попов В.В., Богомякова О.Б., Василькив Л.М., Тулупов А.А., Сагдеев Р.З., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Станкевич Ю.А., Попов В.В., Богомякова О.Б., Василькив Л.М., Тулупов А.А., Сагдеев Р.З.</copyright-holder><copyright-holder xml:lang="en">Stankevich Y.A., Popov V.V., Bogomyakova O.B., Vasilkiv L.M., Tulupov A.A., Sagdeev R.Z.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1215">https://www.nii-kpssz.com/jour/article/view/1215</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения</p><p>Инсульт является одной из ведущих причин инвалидизации и смерти во всем мире. Минимизация последствий заболевания и потенциация восстановления функционально значимых зон головного мозга представляет собой важную задачу нейрореабилитации. При этом поиск эффективных стратегий реабилитации продолжается с учетом расширения знаний в области нейропластичности на основе возможностей нейровизуализации в изучении механизмов постинсультной структурно-функциональной реорганизации головного мозга.</p></sec><sec><title> </title><p> </p></sec><sec><title>Резюме</title><p>Резюме</p><p>Нейропластичность головного мозга (ГМ) человека характеризуется способностью к изменению его организации в результате адаптации к внешним или внутренним стимулам. Локальные поражения головного мозга, например во время инсульта, приводят к функциональным и когнитивным нарушениям, что проявляется неврологическим дефицитом. Существующие методы нейровизуализации позволяют исследовать как морфо-анатомические, так и функциональные перестройки головного мозга. Методы постинсультной реабилитации наряду с возможностями визуализации процессов нейропластичности ГМ дают возможность оценивать эффективность проводимых мероприятий и восстановление пациента. В обзоре проведен ретроспективный анализ исследований механизмов нейропластичности ГМ и их связи с последними достижениями в нейрореабилитации на примере ишемического инсульта. Своевременное и адекватное использование реабилитационных практик в постинсультном периоде необходимо для наиболее эффективного восстановления пациента с учетом оптимизации экономических затрат.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights</p><p>Stroke is one of the leading causes of death and disability worldwide. Minimizing the consequences of the disease and potentiating the restoration of functionally significant areas of the brain is an important task of neurorehabilitation. At the same time, the search for effective rehabilitation strategies continues, taking into account the expansion of knowledge in the field of neuroplasticity based on the progress of neuroimaging capabilities in studying the mechanisms of post-stroke structural and functional reorganization of the brain.</p></sec><sec><title> </title><p> </p></sec><sec><title>Abstract</title><p>Abstract</p><p>Neuroplasticity of the human brain is characterized by the ability to change its organization as a result of adaptation to external or internal stimuli. Local brain lesions, for example during a stroke, lead to functional and cognitive impairments of the brain, which is manifested by neurological deficits. Existing neuroimaging methods allow us to study both morpho-anatomical and functional brain rearrangements. Post-stroke rehabilitation methods, along with the possibilities of visualizing the processes of neuroplasticity of brain, make it possible to evaluate the effectiveness of the measures taken and the patient's recovery. In this review, we aimed to conduct a retrospective analysis of studies on the mechanisms of neuroplasticity of brain and their relationship to recent advances in neurorehabilitation using the example of ischemic stroke. Timely and adequate use of rehabilitation practices in the post-stroke period is necessary for the most effective recovery of the patient while optimizing economic costs.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Нейропластичность</kwd><kwd>Нейровизуализация</kwd><kwd>Нейрореабилитация</kwd><kwd>Ишемический инсульт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Neuroplasticity</kwd><kwd>Neuroimaging</kwd><kwd>Neurorehabilitation</kwd><kwd>Ischemic stroke</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Ю.А. Станкевич, А.А. Тулупов, О.Б. Богомякова, Л.М. Василькив и Р.З. Сагдеев благодарят Российский научный фонд (проект № 19-75-20093) за финансовую поддержку в проведении исследований.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Puderbaugh M., Emmady P.D. Neuroplasticity. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023. Available at: https://www.ncbi.nlm.nih.gov/books/NBK557811/. (accessed 09.10.2024)</mixed-citation><mixed-citation xml:lang="en">Puderbaugh M., Emmady P.D. Neuroplasticity. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023. Available at: https://www.ncbi.nlm.nih.gov/books/NBK557811/. 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