kpcczКомплексные проблемы сердечно-сосудистых заболеванийComplex Issues of Cardiovascular Diseases2306-12782587-9537Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”10.17802/2306-1278-2022-11-4-191-200kpccz-1255Research ArticleОНЛАЙН. В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ. КАРДИОЛОГИЯ, ВНУТРЕННИЕ БОЛЕЗНИONLINE. TO HELP PRACTITIONER. CARDIOLOGY, INTERNAL MEDICINEЧрескожная неинвазивная вегетативная стимуляция: возможности и перспективы метода в практике специалистов по внутренним болезнямPercutaneous non-invasive stimulation: possibilities and prospects of the method in the practice of specialists in internal diseaseshttps://orcid.org/0000-0002-4453-8430ДрапкинаО. М.DrapkinaO. M.

Драпкина Оксана Михайловна, академик РАН, доктор медицинских наук, профессор директор

Петроверигский пер., 10, стр. 3, Москва, 101990

Drapkina Oksana M., Academician of the Russian Academy of Sciences, PhD, Professor, Director

10, bld. 3, Petroverigsky Ln., Moscow, 101990 

https://orcid.org/0000-0002-5384-3795ДжиоеваО. Н.DzhioevaO. N.

Джиоева Ольга Николаевна, доктор медицинских наук старший научный сотрудник отдела фундаментальных и прикладных аспектов ожирения

Петроверигский пер., 10, стр. 3, Москва, 101990

Dzhioeva Olga N., PhD, Senior Researcher at the Department of Fundamental and Applied Aspects of Obesity

10, bld. 3, Petroverigsky Ln., Moscow, 101990 

https://orcid.org/0000-0001-8993-7892РогожкинаЕ. А.RogozhkinaE. A.

Рогожкина Елизавета Александровна, клинический ординатор 

Петроверигский пер., 10, стр. 3, Москва, 101990

Rogozhkina Elizaveta A., Medical Resident 

10, bld. 3, Petroverigsky Ln., Moscow, 101990 

lizarogozkina@gmail.comhttps://orcid.org/0000-0002-8638-7327ШварцЕ. Н.ShvartsE. N.

Шварц Елена Николаевна, лаборант-исследователь отдела координации фундаментальной научной деятельности

Петроверигский пер., 10, стр. 3, Москва, 101990

Shvarts Elena N., Research Assistant at the Department of Fundamental Scientific Coordination

10, bld. 3, Petroverigsky Ln., Moscow, 101990 

https://orcid.org/0000-0003-3967-3950КиселевА. Р.KiselevA. R.

Киселев Антон Робертович, доктор медицинских наук руководитель отдела координации фундаментальной научной деятельности

Петроверигский пер., 10, стр. 3, Москва, 101990

Kiselev Anton R., PhD, Head of the Department of Fundamental Scientific Coordination

10, bld. 3, Petroverigsky Ln., Moscow, 101990 

Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр терапии и профилактической медицины» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution “National Medical Research Center for Therapy and Preventive Medicine” of the Ministry of Healthсare of the Russian FederationRussian Federation202211012023114191200Copyright © Драпкина О.М., Джиоева О.Н., Рогожкина Е.А., Шварц Е.Н., Киселев А.Р., 20232023Драпкина О.М., Джиоева О.Н., Рогожкина Е.А., Шварц Е.Н., Киселев А.Р.Drapkina O.M., Dzhioeva O.N., Rogozhkina E.A., Shvarts E.N., Kiselev A.R.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nii-kpssz.com/jour/article/view/1255

В статье приведен обзор ключевых исследований по стимуляции блуждающего нерва. Данный метод влияет на нервные волокна внутренних и наружных нервных сплетений, усиливая парасимпатическое действие. Благодаря такому воздействию в различных экспериментальных и клинических исследованиях достигнут положительный терапевтический эффект в лечении неврологических, кардиологических заболеваний, метаболического синдрома и ожирения. Показано, что стимуляция блуждающего нерва приводит к уменьшению количества приступов эпилепсии, нарушений ритма сердца, прогностически благоприятна для лечения ишемии и реперфузионного повреждения миокарда. В недавних исследованиях изучен воспалительный рефлекс, участвующий в патогенезе ожирения. Роль биоэлектронной стимуляции блуждающего нерва активно исследуется для лечения ожирения и метаболического синдрома.

The article provides an overview of key studies on vagus nerve stimulation. The vagus nerve stimulation method affects the nerve fibers of the internal and external nerve plexuses, enhancing the parasympathetic effect. The positive therapeutic effect has been achieved in various experimental and clinical studies on the treatment of neurological and cardiac diseases, metabolic syndrome, and obesity. It has been shown that vagus nerve stimulation reduces epileptic seizures frequency, cardiac arrhythmias, and is prognostically favorable for the treatment of ischemia and reperfusion injury of the myocardium. Recent studies have examined the inflammatory reflex involved in the pathogenesis of obesity. The role of bioelectronic vagus nerve stimulation is being actively investigated for the treatment of obesity and metabolic syndrome.

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The authors declare that there are no conflicts of interest present.