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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2023-12-1-94-106</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1310</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИТИЧЕСКИЙ ОБЗОР. Кардиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW. Cardiology</subject></subj-group></article-categories><title-group><article-title>Эволюционирование торсионных механизмов в детском возрасте: современный взгляд на природу вращательной механики левого желудочка</article-title><trans-title-group xml:lang="en"><trans-title>Evolution of twisting mechanisms in childhood: a modern view on the nature of left ventricular rotational mechanisms</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3081-9477</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлюкова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlyukova</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлюкова Елена Николаевна, доктор медицинских наук, профессор заведующая отделением атеросклероза и хронической ишемической болезни сердца, </p><p>ул. Киевская, 111А, Томск, 634012</p></bio><bio xml:lang="en"><p>Pavlyukova Elena N., PhD, Professor, Head of the Department of Atherosclerosis and Ischemic Heart Disease of the Research Institute of Cardiology,</p><p>111A, Kievskaya St., Tomsk, 634012</p></bio><email xlink:type="simple">pavluk@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5550-5925</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колосова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolosova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колосова Марина Владимировна, доктор медицинских наук профессор кафедры детских болезней, </p><p>Московский тракт, 2, Томск, 634050</p></bio><bio xml:lang="en"><p>Kolosova Marina V., PhD, Professor at the Department of Pediatric Diseases,</p><p>2, Moskovsky trakt, Tomsk, 634050</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7556-9379</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Унашева</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Unasheva</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Унашева Аниса Исламгалиевна, аспирант, </p><p>ул. Киевская, 111А, Томск, 634012</p></bio><bio xml:lang="en"><p>Unasheva Anisa I., Postgraduate Student of the Research Institute of Cardiology,</p><p>111A, Kievskaya St., Tomsk, 634012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7011-4316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карпов Ростислав Сергеевич, академик РАН, доктор медицинских наук, профессор научный руководитель,</p><p>ул. Киевская, 111А, Томск, 634012</p></bio><bio xml:lang="en"><p>Karpov Rostislav S., Academician of the Russian Academy of Sciences, PhD, Professor, Head of Science of the Research Institute of Cardiology,</p><p>111A, Kievskaya St., Tomsk, 634012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт кардиологии Федерального государственного бюджетного научного учреждения «Томский национальный исследовательский медицинский центр Российской академии наук» (НИИ кардиологии Томского НИМЦ)<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Scientific Institution “Tomsk National Research Medical Center of the Russian Academy of Sciences” (Tomsk NRMC)<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Сибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Siberian State Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2023</year></pub-date><volume>12</volume><issue>1</issue><fpage>94</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Павлюкова Е.Н., Колосова М.В., Унашева А.И., Карпов Р.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Павлюкова Е.Н., Колосова М.В., Унашева А.И., Карпов Р.С.</copyright-holder><copyright-holder xml:lang="en">Pavlyukova E.N., Kolosova M.V., Unasheva A.I., Karpov R.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1310">https://www.nii-kpssz.com/jour/article/view/1310</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения. Предложена гипотеза эволюционирования типов скручивания ЛЖ, которая основана на трансформации типов скручивания ЛЖ как обязательном условии постнатального роста и развития камер сердца у здоровых детей и подростков. В перспективе переход одного типа скручивания ЛЖ в другой позволит диагностировать преобладание роста и созревания фиброскелета, верхушки, vortex cordis, трабекулярного аппарата, а также создавать карты индивидуального темпа развития и роста сердца в детском и подростковом возрастах.</p></sec><sec><title>Резюме</title><p>Резюме. Современные данные о характере механики левого желудочка (ЛЖ) в постнатальном онтогенезе у здоровых детей и подростков, рожденных доношенными, имеют фундаментальный характер, поскольку позволяют не только определять онтогенетически обусловленные варианты индивидуального развития контрактильно-ротационных механизмов ЛЖ в процессе роста и развития, но и при необходимости дают возможность выявлять на ранних этапах субклиническую дисфункцию, контролировать эффективность комплексных терапевтических и реабилитационных мероприятий. В статье подробно проанализирован впервые установленный факт отсутствия статичности выделенных различных форм скручивания ЛЖ в систолу и способности их трансформации в процессе роста и развития. Данный факт положен в основу авторской оригинальной гипотезы эволюционирования моделей скручивания ЛЖ, обеспечивающего оптимальный темп индивидуального онтогенеза детского и подросткового сердца в постнатальный период. Гипотеза эволюционирования типов скручивания левого желудочка основана на современных знаниях о многогранных процессах на тканевом уровне, механике ЛЖ при индивидуальном темпе развития и роста сердца в детском и подростковом возрастах.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights. The hypothesis of the evolution of LV twisting types is proposed, which is based on the gradual transformation of LV twisting types as a prerequisite for postnatal growth and development of heart chambers in healthy children and adolescents. In the future, the transition of one type of LV twist to another will enable us to diagnose the predominance of growth and maturation of the fibrous skeleton, apex, vortex cordis, trabecular apparatus, as well as creating projections of the individual development and growth of the heart in childhood and adolescence.</p></sec><sec><title>Abstract</title><p>Abstract. Modern data on the nature of the mechanics of the left ventricle (LV) in postnatal ontogenesis in healthy children and adolescents born full-term are fundamental, since they allow not only to determine ontogenetically conditioned variants of individual development of contractile-rotational mechanisms of LV in the process of growth and development, but also, if necessary, make it possible to identify subclinical dysfunction in the early stages, monitor the effectiveness of complex therapeutic and rehabilitation measures. The article analyzes newly established fact of the absence of static character of the selected various forms of LV twisting into a systole and the ability of their transformation in the process of growth and development. This fact forms the basis of the author's original hypothesis of “the evolution of LV twisting models”, which provides the optimal ontogenetic growth of the child and adolescent heart in the postnatal period. The hypothesis of “evolution of left ventricular twisting types” is based on modern knowledge about multifaceted processes at the tissue level, the mechanics of LV in the individual rate of development and growth of the heart in childhood and adolescence.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>скручивание левого желудочка</kwd><kwd>апикальная ротация</kwd><kwd>эволюционирования типов скручивания левого желудочка</kwd><kwd>дети</kwd><kwd>рожденные доношенными</kwd></kwd-group><kwd-group xml:lang="en"><kwd>left ventricle twist</kwd><kwd>apical rotation</kwd><kwd>evolution of types of left ventricle twist</kwd><kwd>children born full-term</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Публикация выполнена в соответствии с планом НИИ кардиологии Томского НИМЦ по фундаментальной теме «Фундаментальные аспекты формирования структурно-функциональных изменений сердца и сосудов в разных возрастных группах на доклинической, клинической стадиях и после гемодинамической коррекции сердечно-сосудистых заболеваний».</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Notomi Y., Srinath G., Shiota T., Martin-Miklovic M. 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