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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2023-12-3-15-26</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1368</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Сердечно-сосудистая хирургия</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiovascular surgery</subject></subj-group></article-categories><title-group><article-title>БИМАММАРНОЕ КОРОНАРНОЕ ШУНТИРОВАНИЕ: ПЯТНАДЦАТИЛЕТНИЙ ОПЫТ</article-title><trans-title-group xml:lang="en"><trans-title>BILATERAL INTERNAL THORACIC ARTERY GRAFTING: FIFTEEN YEARS OF EXPERIENCE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1746-8895</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролов</surname><given-names>Алексей Витальевич</given-names></name><name name-style="western" xml:lang="en"><surname>Frolov</surname><given-names>Alexey V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук старший научный сотрудник лаборатории реконструктивной и рентгенэндоваскулярной хирургии сердца и сосудов отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, Senior Researcher at the Laboratory of Endovascular and Reconstructive Cardiovascular Surgery, Department of Cardiovascular Surgery, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">kjerne@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3539-0291</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Загородников</surname><given-names>Никита Игоревич</given-names></name><name name-style="western" xml:lang="en"><surname>Zagorodnikov</surname><given-names>Nikita I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>Postgraduate student, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">zn.cardio@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9070-5527</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>Сергей Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>Sergey V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук ведущий научный сотрудник лаборатории реконструктивной и рентгенэндоваскулярной хирургии сердца и сосудов отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>MD, PhD, Leading Researcher at the Laboratory of Endovascular and Reconstructive Cardiovascular Surgery, Department of Cardiovascular Surgery, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">kjerne@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3882-709X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасов</surname><given-names>Роман Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasov</surname><given-names>Roman S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук заведующий лабораторией реконструктивной и рентгенэндоваскулярной хирургии сердца и сосудов отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>MD, PhD, Head of the Laboratory of Endovascular and Reconstructive Cardiovascular Surgery, Department of Cardiovascular Surgery, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">kjerne@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6981-9661</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>Леонид Семенович</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>Leonid S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>академик РАН, доктор медицинских наук, профессор главный научный сотрудник федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>Academician of the Russian Academy of Sciences, Chief Researcher, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">kjerne@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2023</year></pub-date><volume>12</volume><issue>3</issue><fpage>15</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фролов А.В., Загородников Н.И., Иванов С.В., Тарасов Р.С., Барбараш Л.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Фролов А.В., Загородников Н.И., Иванов С.В., Тарасов Р.С., Барбараш Л.С.</copyright-holder><copyright-holder xml:lang="en">Frolov A.V., Zagorodnikov N.I., Ivanov S.V., Tarasov R.S., Barbarash L.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1368">https://www.nii-kpssz.com/jour/article/view/1368</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения</p></sec><sec><title> </title><p> </p></sec><sec><title>Цель</title><p>Цель. Оценить результаты бимаммарного коронарного шунтирования (БиМКШ) по данным более чем 15-летнего наблюдения.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследованы 232 пациента, поступившие в кардиохирургическое отделение для проведения коронарного шунтирования (КШ). Все пациенты разделены на две группы в зависимости от использования одной или двух внутренних грудных артерий. В первую и вторую группы вошло равное количество больных – по 116 (50%) в каждой. Оценены результаты отдаленного (более 15 лет) послеоперационного периода.</p></sec><sec><title>Результаты</title><p>Результаты. БиМКШ сопоставимо со стандартным КШ по таким серьезным неблагоприятным сердечно-сосудистым событиям, как повторная реваскуляризация миокарда, инсульт, а также по комбинированной конечной точке, представленной инфарктом миокарда, инсультом, повторной реваскуляризацией миокарда, смертью пациента или их сочетанием. Вместе с тем БиМКШ превосходит стандартное КШ в свободе от инфаркта миокарда, случаях смерти от любых причин, демонстрируя более высокую продолжительность жизни больных после операции (p = 0,011), а также улучшает фракцию выброса левого желудочка и снижает функциональный класс стенокардии напряжения. Кроме этого, в настоящем исследовании установлено, что выраженность атеросклероза в коронарных артериях ниже после шунтирования аутоартериальными кондуитами, что, вероятно, связано с их коронаропротективным действием.</p></sec><sec><title>Заключение</title><p>Заключение. БиМКШ является безопасной процедурой, сравнимой с классическим КШ, однако демонстрирует более благоприятные отдаленные клинические и ангиографические результаты.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights</p></sec><sec><title> </title><p> </p></sec><sec><title>Aim</title><p>Aim. To analyze long-term results of BITA grafting in terms of more than 15 years follow-up.</p></sec><sec><title>Methods</title><p>Methods. The study included 232 patients who were admitted at the Cardiac Surgery Department for coronary artery bypass grafting (CABG). All patients were divided into 2 groups depending on usage of single or bilateral internal thoracic artery conduits. Both groups included an equal number of patients 116 (50%). Long-term results were assessed in terms of more than 15 years follow-up.</p></sec><sec><title>Results</title><p>Results. BITA grafting is comparable with CABG in such major adverse cardiac and cerebrovascular events as repeated myocardial revascularization, stroke, and in combined endpoint such as myocardial infarction (MI), stroke, repeated myocardial revascularization, or patient’s death within 15 years. However, the BITA group is superior to the CABG group in freedom from MI, all-cause deaths, showing a higher life expectancy after surgery (p = 0.011), and improved left ventricular ejection fraction and decreased functional class of angina. Moreover, in the present research it was confirmed that the severity of atherosclerosis in the coronary arteries is lower after bypassing with autogenous arterial conduits.</p></sec><sec><title>Conclusion</title><p>Conclusion. BITA is safe procedure comparable with CABG, however, it has more advantageous long-term clinical and angiographic results.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Отдаленный послеоперационный период</kwd><kwd>Бимаммарное коронарное шунтирование</kwd><kwd>Отдаленные результаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Long-term follow-up</kwd><kwd>Bilateral internal thoracic artery grafting</kwd><kwd>Outcome</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Авторы заявляют об отсутствии финансирования исследования.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bonatti J., Wallner S., Crailsheim I., Grabenwöger M., Winkler B. Minimally invasive and robotic coronary artery bypass grafting-a 25-year review. 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