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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2023-12-4S-44-52</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1443</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Кардиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiology</subject></subj-group></article-categories><title-group><article-title>ИЗМЕНЕНИЯ ПЛОТНОСТИ ИСТОЧНИКОВ ТЕТА-АКТИВНОСТИ  У КАРДИОХИРУРГИЧЕСКИХ ПАЦИЕНТОВ ПОСЛЕ МУЛЬТИЗАДАЧНОГО КОГНИТИВНОГО ТРЕНИНГА</article-title><trans-title-group xml:lang="en"><trans-title>THETA CURRENT SOURCES DENSITY CHANGES IN CARDIAC SURGERY PATIENTS COGNITIVE AFTER MULTITASKING TRAINING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6391-0170</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Ирина Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>Irina V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук ведущий научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>MD., PhD, Leading Researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">iriz78@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9750-5536</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куприянова</surname><given-names>Дарья Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kupriyanova</surname><given-names>Darya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>Junior Researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">iriz78@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4339-8680</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сырова</surname><given-names>Ирина Даниловна</given-names></name><name name-style="western" xml:lang="en"><surname>Syrova</surname><given-names>Irina D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук врач-невролог, научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>MD., PhD, Neurologist, Researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">iriz78@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8908-2070</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соснина</surname><given-names>Анастасия Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Sosnina</surname><given-names>Anastasia S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук врач-кардиолог, научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>MD., PhD, Cardiologist, Researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">iriz78@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8260-8033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубникова</surname><given-names>Ольга Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Trubnikova</surname><given-names>Olga A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук заведующая лабораторией нейрососудистой патологии отдела клинической кардиологии федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>MD., PhD, Head of the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">iriz78@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>29</day><month>12</month><year>2023</year></pub-date><volume>12</volume><issue>4S</issue><issue-title>приложение</issue-title><fpage>44</fpage><lpage>52</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тарасова И.В., Куприянова Д.С., Сырова И.Д., Соснина А.С., Трубникова О.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Тарасова И.В., Куприянова Д.С., Сырова И.Д., Соснина А.С., Трубникова О.А.</copyright-holder><copyright-holder xml:lang="en">Tarasova I.V., Kupriyanova D.S., Syrova I.D., Sosnina A.S., Trubnikova O.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1443">https://www.nii-kpssz.com/jour/article/view/1443</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения</p><p>Проведена оценка изменений плотности источников тета-активности у пациентов, прошедших мультизадачный когнитивный тренинг в раннем послеоперационном периоде кардиохирургического вмешательства.</p><p>Установлено, что у кардиохирургических пациентов после мультизадачного когнитивного тренинга наблюдается достоверно меньшая плотность источников тета-ритма до операции по сравнению с послеоперационными данными с локализацией наиболее сильных различий в полях Бродмана 7, 19 и 31, относящихся к структурам парието-окципитальных долей головного мозга, кунеуса и прекунеуса.</p></sec><sec><title> </title><p> </p></sec><sec><title>Резюме</title><p>Резюме</p></sec><sec><title>Цель</title><p>Цель. Влияние методов когнитивного восстановления на деятельность головного мозга остается значимым вопросом современного здравоохранения. Целью настоящей работы явилась оценка изменений плотности источников тета-активности с помощью стандартизованной электромагнитной томографии низкого разрешения (sLORETA) у пациентов, которые прошли курс мультизадачного когнитивного тренинга в послеоперационном периоде коронарного шунтирования (КШ).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследовании участвовали 30 пациентов в возрасте от 45 до 75 лет, подвергшиеся плановому КШ. Клинические и нейрофизиологические обследования проводились за 2–3 дня до и через 11–12 дней после вмешательства. Когнитивный тренинг выполнен начиная с 3–4-х сут после КШ до выписки из стационара и состоял из моторной задачи в виде нажатия клавиши на клавиатуре компьютера в ответ на появляющийся на экране объект и трех последовательно сменяющих друг друга когнитивных задач (обратный счет, вербальная беглость и придумывание способов необычного использования обычного предмета).</p></sec><sec><title>Результаты</title><p>Результаты. У пациентов, прошедших мультизадачный когнитивный тренинг, установлена достоверно меньшая плотность источников тока тета-ритма (t&lt;–3,89; p&lt;0,002) до КШ по сравнению с послеоперационными данными с локализацией наиболее сильных различий в парието-окципитальных долях головного мозга, кунеуса и прекунеуса (поля Бродмана 7, 19 и 31).</p></sec><sec><title>Заключение</title><p>Заключение. Результаты настоящего исследования могут быть полезны для лучшего понимания патогенетических механизмов, лежащих в основе когнитивных нарушений, обусловленных кардиохирургическими вмешательствами.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights</p><p>We estimated theta current sources density changes in patients who received cognitive multitasking training in the early postoperative period of cardiac surgery.</p><p>Patients with cognitive multitasking training had a significantly lower theta current source density (t&lt;–3.89; p&lt;0.002) before surgery compared to baseline. The strongest differences were localized in Brodmann areas 7, 19 and 31 which related to the structures of the parieto-occipital lobes of the brain, cuneus and precuneus.</p></sec><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec><sec><title>Abstract</title><p>Abstract</p></sec><sec><title>Aim</title><p>Aim. The effect of cognitive recovery techniques on brain activity remains a significant issue in modern health care. The aim of this study was to estimate theta current sources density changes using standardized low resolution electromagnetic tomography – sLORETA – (standardized low resolution brain electromagnetic tomography) in patients who have received cognitive multitasking training (CMT) in the postoperative period of coronary artery bypass grafting (CABG).</p></sec><sec><title>Methods</title><p>Methods. The study included 30 patients aged between 45 and 75 years who underwent routine CABG. Clinical and neurophysiological examinations were carried out 2–3 days before surgery and 11–12 days after CABG. The cognitive training started 3–4 days after CABG and lasted until discharge and consisted of a motor task - a keypress in response to an object appearing on the screen and three consecutive cognitive tasks (counting backwards, verbal fluency and unusual use of an ordinary object).</p></sec><sec><title>Results</title><p>Results. Patients with CMT had lower theta current source density (t&lt;–3.89; p&lt;0.002) before CABG as compared to postoperative data, the most significant differences were noted in parieto-occipital lobes of the brain, cuneus and precuneus (Brodmann areas 7, 19 and 31).</p></sec><sec><title>Conclusion</title><p>Conclusion. The results of our research contribute to a better understanding of the pathogenetic mechanisms underlying postoperative cognitive impairments in cardiac surgery patients.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Электроэнцефалограмма</kwd><kwd>sLORETA</kwd><kwd>Когнитивный тренинг</kwd><kwd>Мультизадачность</kwd><kwd>Ишемия мозга</kwd><kwd>Коронарное шунтирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Electroencephalogram sLORETA</kwd><kwd>Cognitive training</kwd><kwd>Multitasking</kwd><kwd>Cerebral ischemia</kwd><kwd>Coronary artery bypass grafting</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Результаты получены при поддержке Российской Федерации в лице Министерства науки и высшего образования РФ в рамках Соглашения о предоставлении из федерального бюджета грантов в форме субсидий от «30» сентября 2022 г. № 075-15-2022-1202, комплексной научно-технической программы полного инновационного цикла «Разработка и внедрение комплекса технологий в областях разведки и добычи твердых полезных ископаемых, обеспечения промышленной безопасности, биоремедиации, создания новых продуктов глубокой переработки из угольного сырья при последовательном снижении экологической нагрузки на окружающую среду и рисков для жизни населения» (утвержденной распоряжением Правительства Российской Федерации от 11 мая 2022 г. № 1144-р).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gerstenecker A., Norling A.M., Jacob A., Lazar R.M. 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