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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2025-14-2-200-210</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1534</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОНЛАЙН. АНАЛИТИЧЕСКИЙ ОБЗОР. Кардиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ONLINE. REVIEW. CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>ФИБРИЛЛЯЦИЯ ПРЕДСЕРДИЙ: ОЦЕНКА РИСКА РАЗВИТИЯ И ПРИНЦИПЫ ПЕРВИЧНОЙ ПРОФИЛАКТИКИ</article-title><trans-title-group xml:lang="en"><trans-title>ATRIAL FIBRILLATION: RISK ASSESSMENT AND PRINCIPLES OF PRIMARY PREVENTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9083-8944</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тютелева</surname><given-names>Наталья Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Tyuteleva</surname><given-names>Natalia N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук ассистент кафедры госпитальной терапии и кардиологии им. М.С. Кушаковского федерального государственного бюджетного образовательного учреждения высшего образования «Северо-западный государственный медицинский университет им. И.И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Российская Федерация</p></bio><bio xml:lang="en"><p>MD, PhD, Assistant at the Department of Advanced Therapy and Cardiology named after M.S. Kushakovsky, Federal State Budgetary Educational Institution of Higher Education “North-Western State Medical University named after. I.I. Mechnikov” Ministry of Healthcare of the Russian Federation, St. Petersburg, Russian Federation</p></bio><email xlink:type="simple">nesteraza84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7827-1052</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олесин</surname><given-names>Александр Иосифович</given-names></name><name name-style="western" xml:lang="en"><surname>Olesin</surname><given-names>Aleksandr I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук профессор кафедры госпитальной терапии и кардиологии им. М.С. Кушаковского федерального государственного бюджетного образовательного учреждения высшего образования «Северо-западный государственный медицинский университет им. И.И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, Professor, Department of Advanced Therapy and Cardiology named after M.S. Kushakovsky, Federal State Budgetary Educational Institution of Higher Education “North-Western State Medical University named after. I.I. Mechnikov” Ministry of Healthcare of the Russian Federation, St. Petersburg, Russian Federation</p></bio><email xlink:type="simple">olesin58@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3350-3088</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинова</surname><given-names>Ирина Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinova</surname><given-names>Irina V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук доцент кафедры госпитальной терапии и кардиологии им. М.С. Кушаковского федерального государственного бюджетного образовательного учреждения высшего образования «Северо-западный государственный медицинский университет им. И.И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Российская Федерация</p></bio><bio xml:lang="en"><p>MD, PhD, Associate Professor at the Department of Advanced Therapy and Cardiology named after M.S. Kushakovsky, Federal State Budgetary Educational Institution of Higher Education “North-Western State Medical University named after. I.I. Mechnikov” Ministry of Healthcare of the Russian Federation, St. Petersburg, Russian Federation</p></bio><email xlink:type="simple">i.konsta@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-западный государственный медицинский университет им. И.И. Мечникова» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of Higher Education “North-Western State Medical University named after. I.I. Mechnikov” Ministry of Healthcare of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>05</day><month>05</month><year>2025</year></pub-date><volume>14</volume><issue>2</issue><fpage>200</fpage><lpage>210</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тютелева Н.Н., Олесин А.И., Константинова И.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Тютелева Н.Н., Олесин А.И., Константинова И.В.</copyright-holder><copyright-holder xml:lang="en">Tyuteleva N.N., Olesin A.I., Konstantinova I.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1534">https://www.nii-kpssz.com/jour/article/view/1534</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения</p><p>Описано современное состояние проблемы оценки риска развития, ранней диагностики и первичной профилактики на стадии префибрилляции предсердий.</p></sec><sec><title> </title><p> </p></sec><sec><title>Резюме</title><p>Резюме</p><p>В обзоре рассмотрены принципы первичной профилактики фибрилляции предсердий с учетом механизмов ее формирования и факторов риска развития этой аритмии. Первая стадия префибрилляции предсердий характеризуется наличием потенциально модифицируемых факторов риска ее возникновения, вторая – электрическим и структурным ремоделированием сердца. Представлены данные литературы об эффективности коррекции потенциально модифицируемых факторов риска, использовании фармакологической и немедикаментозной терапии на этапе префибрилляции предсердий.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights</p><p>The review describes the current state of the problem of assessing the risk of development, early diagnosis and primary prevention of atrial pre-fibrillation.</p></sec><sec><title> </title><p> </p></sec><sec><title>Abstract</title><p>Abstract</p><p>The presented review describes the principles of primary prevention of atrial fibrillation from the standpoint of assessing the mechanisms of its formation and the risk of developing this arrhythmia. The first stage of atrial pre-fibrillation is characterized by the presence of potentially modifiable risk factors for its occurrence, and the second – by electrical and structural remodeling of the heart. The article presents the results of correction of potentially modifiable risk factors of atrial pre-fibrillation, and evaluates the effectiveness of using pharmacological and non-drug therapy. The article presents literature data on the effectiveness of correction of potentially modifiable risk factors, the use of pharmacological and non-drug therapy at the stages of atrial pre-fibrillation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Префибрилляция предсердий</kwd><kwd>Первичная профилактика фибрилляции предсердий</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Atrial pre-fibrillation</kwd><kwd>Primary prevention of atrial fibrillation</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Авторы заявляют об отсутствии финансирования исследования.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аракелян М.Г., Бокерия Л.А., Васильева Е.Ю., Голицын С.П., Голухова Е.З., Горев М.В., Давтян К.В., Драпкина О.М. и др.. Фибрилляция и трепетание предсердий. Клинические рекомендации 2020. 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