kpcczКомплексные проблемы сердечно-сосудистых заболеванийComplex Issues of Cardiovascular Diseases2306-12782587-9537Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”10.17802/2306-1278-2025-14-4-123-134kpccz-1560Research ArticleАНАЛИТИЧЕСКИЙ ОБЗОР. Сердечно-сосудистая хирургия. Патологическая физиологияREVIEW. Cardiovascular Surgery. Pathological PhysiologyМОРФОФУНКЦИОНАЛЬНАЯ СИСТЕМА КОНДУИТ-АРТЕРИЯ ПРИ ОСТРОМ КОРОНАРНОМ СИНДРОМЕMORPHOFUNCTIONAL SYSTEM CONDUIT-ARTERY IN ACUTE CORONARY SYNDROMEhttps://orcid.org/0000-0002-1746-8895ФроловАлексей ВитальевичFrolovAleksey V.

доктор медицинских наук врач – сердечно-сосудистый хирург, ведущий научный сотрудник лаборатории рентгенэндоваскулярной и реконструктивной хирургии сердца и сосудов отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация

Doct. of Med. Sci., Cardiovascular Surgeon, Leading Researcher of the Laboratory of Reconstructive and Interventional Surgery of Heart and Vessels, Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation

kjerne@yandex.ruФедеральной государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»РоссияFederal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”Russian Federation202531082025144123134Copyright © Фролов А.В., 20252025Фролов А.В.Frolov A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nii-kpssz.com/jour/article/view/1560Основные положения

Основные положения

 

 

Резюме

Резюме

В обзоре рассмотрена аутобионическая морфофункциональная система кондуит-артерия, формируемая хирургическим путём в ходе коронарного шунтирования, включающая такие элементы, как приносящий (кондуит) и принимающий (коронарная артерия) сосуды, а также кровь, с позиции её функционирования в условиях острого коронарного события. Для фундаментального понимания текущего статуса открытой реваскуляризации миокарда, которая имеет множество нерешённых вопросов, включая, время выполнения оперативного вмешательства, объём, лекарственная терапия и другие, показаны различные патофизиологические аспекты, отражающие ответ системы и её элементов на сосудистую катастрофу. В данном контексте приоткрываются новые горизонты для дальнейшего изучения хирургической реваскуляризации, которые помогут оптимизировать подход к этому виду лечения у пациентов с острым коронарным синдромом.

Highlights

Highlights

 

 

Abstract

Abstract

 The review considers the autobionic morphofunctional conduit-artery system, formed surgically during coronary artery bypass grafting, including such elements as the afferent (conduit) and receiving (coronary artery) vessels, as well as blood, from the position of its functioning in conditions of an acute coronary event. For a fundamental understanding of the current status of open myocardial revascularization, which has many unresolved issues, including the timing of surgery, volume, drug therapy, etc., various pathophysiological aspects reflecting the response of the system and its elements to a vascular catastrophe are shown. In this context, new horizons are opened for further study of surgical revascularization, which will help optimize the approach to this type of treatment in patients with acute coronary syndrome.

Морфофункциональная системаОстрый коронарный синдромКоронарное шунтиро-ваниеMorphofunctional systemAcute coronary syndromeCoronary artery bypass graftingИсследование выполнено в рамках фундаментальной научной темы № 0419-2022-0002 «Разработка инновационных моделей управления риском развития болезней системы кровообращения с учетом коморбидности на основе изучения фундаментальных, клинических, эпидемиологических механизмов и организационных технологий медицинской помощи в условиях промышленного региона Сибири» (научный руководитель – академик РАН О.Л. Барбараш). № госрегистрации 122012000364-5 от 20.01.2022.ReferencesGalzerano D., Kholaif N., Al Amro B., Al Admawi M., Eltayeb A., Alshammari A., Di Salvo G., Al-Halees Z.Y. The Ross Procedure: Imaging, Outcomes and Future Directions in Aortic Valve Replacement. J Clin Med. 2024;13(2):630. DOI: 10.3390/jcm13020630Galzerano D., Kholaif N., Al Amro B., Al Admawi M., Eltayeb A., Alshammari A., Di Salvo G., Al-Halees Z.Y. 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The authors declare that there are no conflicts of interest present.