kpcczКомплексные проблемы сердечно-сосудистых заболеванийComplex Issues of Cardiovascular Diseases2306-12782587-9537Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”10.17802/2306-1278-2024-13-4S-241-253kpccz-1567Research ArticleАНАЛИТИЧЕСКИЙ ОБЗОР. Анестезиология и реаниматологияREVIEWS. Anaesthesiology and intensive careДИАГНОСТИЧЕСКАЯ ЗНАЧИМОСТЬ МЕТОДА БЛИЖНЕЙ ИНФРАКРАСНОЙ СПЕКТРОСКОПИИ В ПРОФИЛАКТИКЕ ЦЕРЕБРАЛЬНОГО ПОВРЕЖДЕНИЯ ПРИ ХИРУРГИЧЕСКОЙ КОРРЕКЦИИ ВРОЖДЕННЫХ ПОРОКОВ СЕРДЦА У ДЕТЕЙDIAGNOSTIC SIGNIFICANCE OF THE NEAR-INFRARED SPECTROSCOPY IN THE PREVENTION OF CEREBRAL INJURY DURING SURGICAL CORRECTION OF CONGENITAL HEART DEFECTS IN CHILDRENhttps://orcid.org/0000-0003-0246-3466МихайловаАлена АлександровнаMikhailovaAlyona A.

младший научный сотрудник лаборатории органопротекции у детей с врожденными пороками сердца отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация

Junior Researcher at the Laboratory of Organoprotection in Children with Congenital Heart Defects, Department of Heart and Vascular Surgery, Federal State Budgetary Institution “Research Institute for Complex Issue of Cardiovascular Diseases”, Kemerovo, Russian Federation

carfagenez@mail.ruhttps://orcid.org/0000-0002-3899-1642ИвкинАртём АлександровичIvkinArtem A.

кандидат медицинских наук заведующий лабораторией органопротекции у детей с врожденными пороками сердца отдела хирургии сердца и сосудов, научный сотрудник лаборатории анестезиологии-реаниматологии и патофизиологии критических состояний, старший преподаватель научно-образовательного отдела, врач – анестезиолог-реаниматолог федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация

PhD, Head of the Laboratory of Organoprotection in Children with Congenital Heart Defects, Department of Heart and Vascular Surgery, Researcher at the Laboratory of Anesthesiology, Intensive Care and Pathophysiology of Critical Conditions, Senior Lecturer at the Department of Science and Education, Anesthesiologist, Intensive Care Physician at the Federal State Budgetary Institution “Research Institute for Complex Issue of Cardiovascular Diseases”, Kemerovo, Russian Federation

aai-tema@mail.ruhttps://orcid.org/0000-0001-8370-3083ГригорьевЕвгений ВалерьевичGrigorievEvgeny V.

доктор медицинских наук, профессор РАН, заместитель директора по научной и лечебной работе, ведущий научный сотрудник лаборатории анестезиологии-реаниматологии и патофизиологии критических состояний федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация

MD, PhD, Member of the Russian Academy of Sciences, Deputy Director for Research and Clinical Affairs, Leading Researcher at the Laboratory of Anesthesiology, Intensive Care and Pathophysiology of Critical Conditions, Federal State Budgetary Institution “Research Institute for Complex Issue of Cardiovascular Diseases”, Kemerovo, Russian Federation

grigorievev@hotmail.comФедеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»РоссияFederal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”Russian Federation202428122024134S241253Copyright © Михайлова А.А., Ивкин А.А., Григорьев Е.В., 20252025Михайлова А.А., Ивкин А.А., Григорьев Е.В.Mikhailova A.A., Ivkin A.A., Grigoriev E.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nii-kpssz.com/jour/article/view/1567Основные положения

Основные положения

С учетом развития методик искусственного кровообращения при операциях на сердце у детей первостепенное значение имеет проблема интраоперационной защиты органов, в частности церебропротекция – одна из главных задач ведения пациента. Цель данного обзора литературы – определить роль ближневолновой инфракрасной спектроскопии среди множества аппаратных методик мониторинга функции мозга.

Резюме

Резюме

Ближневолновая инфракрасная спектроскопия используется для оценки регионарной тканевой перфузии и оксигенации тканей головного мозга во время операций на сердце, проводимых в условиях искусственного кровообращения (ИК). Данные о корреляции лабораторных маркеров церебрального повреждения с результатами церебральной оксиметрии у детей делают возможным создание эффективных стратегий церебропротекции и профилактики послеоперационной когнитивной дисфункции как части комплексной интраоперационной оценки состояния пациента. Целью представленной работы стал анализ эффективности метода ближней инфракрасной спектроскопии в церебропротекции при коррекции врожденных пороков сердца у детей в условиях ИК. Выполнен обзор литературных источников на русском и английском языках, представленных в базах данных Web of Science, PubMed и eLIBRARY за последние десять лет. Поиск релевантных исследований осуществлен по ключевым словам: «органопротекция», «врожденные пороки сердца», «дети», «искусственное кровообращение», «спектроскопия в около-инфракрасном спектре». Источники, не соответствующие заданным критериям, исключены из обзора. Обосновано применение ближней инфракрасной спектроскопии для оценки церебральной перфузии с целью церебропротекции у детей с врожденными пороками сердца. Показана эффективность церебральной оксиметрии при различных видах оперативных вмешательств на сердце в условиях ИК у детей. Ближневолновая инфракрасная спектроскопия – рутинная методика оценки перфузии мозга для профилактики церебрального повреждения при операциях на сердце в условиях ИК. Приведенные в обзоре данные демонстрируют связь лабораторных маркеров церебрального повреждения с показателями интраоперационной церебральной оксиметрии методом ближней инфракрасной спектроскопии у детей при операциях на сердце в условиях ИК. Необходимы дальнейшие исследования для изучения перспектив описанного метода церебропротекции.

Highlights

Highlights

With the recent advancement in cardiopulmonary bypass techniques in pediatric cardiac surgery, the issue of organ protection during surgery is becoming more urgent, in particular cerebral protection is turning into one of the most important parts of patient management. The aim of this literature review is to determine the role of near-infrared spectroscopy among a variety of techniques for monitoring cerebral function.

 

 

Abstract

Abstract

Near-infrared spectroscopy evaluates regional tissue perfusion and oxygenation of brain tissues during cardiac surgery with cardiopulmonary bypass (CPB). Data on the correlation of laboratory markers of cerebral injury and indicators of cerebral oximetry in children make it possible to create effective strategies of cerebral protection and prevention of postoperative cognitive dysfunction as part of a comprehensive intraoperative assessment of the patient's condition. The aim of the article was to analyze the effectiveness of the near-infrared spectroscopy in cerebral protection during surgical correction of congenital heart defects with CPB in children. The search for Russian and English publications (up to 10 years old) was performed using the following databases: Web of Science, PubMed, E-library. The keywords for the search were: “organ protection”, “congenital heart defects”, “children”, “cardiopulmonary bypass”, “near-infrared spectroscopy”. Publications that did not meet the specified criteria were excluded from the analysis. The findings substantiate the use of near-infrared spectroscopy to assess cerebral perfusion for the purpose of cerebral protection in children with congenital heart defects. The effectiveness of cerebral oximetry in various types of cardiac surgery with CPB in children has been shown. Near-infrared spectroscopy is a routine technique for assessing cerebral perfusion for the prevention of cerebral injury during cardiac surgery with CPB. The data presented in the review demonstrate the relationship between laboratory markers of cerebral injury and indicators of intraoperative cerebral oximetry using near-infrared spectroscopy in children during cardiac surgery with CPB. Further research is needed to explore the prospects of the described method of cerebral protection.

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The authors declare that there are no conflicts of interest present.