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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2025-14-5-16-26</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1573</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Кардиология. Внутренние болезни</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiology. Internal medicine</subject></subj-group></article-categories><title-group><article-title>КАЧЕСТВО ЖИЗНИ И ЭМОЦИОНАЛЬНОЕ СОСТОЯНИЕ ПАЦИЕНТОВ ПОСЛЕ ХИРУРГИЧЕСКОЙ КОРРЕКЦИИ ПРИОБРЕТЕННОГО ПОРОКА МИТРАЛЬНОГО КЛАПАНА ЗАВИСИТ ОТ НАЛИЧИЯ ПРЕДОПЕРАЦИОННОЙ ЛЕГОЧНОЙ ГИПЕРТЕНЗИИ</article-title><trans-title-group xml:lang="en"><trans-title>QUALITY OF LIFE AND EMOTIONAL STATE IN PATIENTS AFTER SURGICAL CORRECTION OF ACQUIRED MITRAL VALVE DISEASE DEPENDS ON THE PRESENCE OF PREOPERATIVE PULMONARY HYPERTENSION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4649-5921</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ляпина</surname><given-names>Ирина Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Lyapina</surname><given-names>Irina N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, научный сотрудник реабилитационной лаборатории отделения клинической кардиологии, кардиолог Центра легочной артериальной гипертензии Федерального государственного бюджетного учреждения “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, Researcher at the Rehabilitation Laboratory of the Department of Clinical Cardiology, Cardiologist of Pulmonary Arterial Hypertension Center, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">zaviirina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7549-8075</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмина</surname><given-names>Юлия Евгеньевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmina</surname><given-names>Yuliya E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, врач-кардиолог ООО “Каноха”, Краснодар, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, cardiologist at the LLC “Kanoha”, Krasnodar, Russian Federation</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9022-8097</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынюк</surname><given-names>Тамила Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Martynyuk</surname><given-names>Tamila V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующая отделением легочной гипертензии и болезней сердца, Научно-исследовательский институт клинической кардиологии им. А.Л. Мясникова, Национальный медицинский исследовательский центр кардиологии им. Е.И. Чазова, Москва, Российская Федерация</p></bio><bio xml:lang="en"><p>Dr. Of Sci. (Med.), Head of the Department of Pulmonary Hypertension and Heart Diseases, A.L. Myasnikov Research Institute of Clinical Cardiology, E.I. Chazov National Medical Research Centre of Cardiology, Moscow, Russian Federation</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5469-7638</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дрень</surname><given-names>Елена Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Dren'</surname><given-names>Elena V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант, младший научный сотрудник лаборатории реабилитации, научный сотрудник лаборатории фиброгенеза миокарда, Федеральное государственное бюджетное учреждение “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD Student, Junior Researcher of Laboratory of Rehabilitation, Laboratory Researcher at the Laboratory of Myocardial Fibrogenesis, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8876-005X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Двадцатов</surname><given-names>Иван Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Dvadtsatov</surname><given-names>Ivan V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, сердечно-сосудистый хирург 1-го кардиохирургического отделения Федерального государственного бюджетного учреждения “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD, Cardiovascular Surgeon of 1st Cardiac Surgery Department, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3224-9727</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Двадцатова</surname><given-names>Полина Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Dvadtsatova</surname><given-names>Polina N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студентка 5 курса Федерального государственного бюджетного образовательного учреждения высшего профессионального образования “Кемеровский государственный медицинский университет” Министерства здравоохранения Российской Федерации, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>5th year student at the Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University” of the Ministry of Health of the Russian Federation, Kemerovo, Russian Federation</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8079-5397</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>Юлия Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>Yulia A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующая лабораторией реабилитации отделения клинической кардиологии Федерального государственного бюджетного учреждения “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>Dr. Of Sci. (Med.), Head of the Rehabilitation Laboratory, Department of Clinical Cardiology, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4642-3610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>Ольга Леонидовна</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>Olga L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>академик РАН, доктор медицинских наук, профессор, руководитель Федерального государственного бюджетного учреждения “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>Academician of RAS, MD, Professor, Head of Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний”<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ООО “Каноха”<country>Россия</country></aff><aff xml:lang="en">LLC “Kanoha”<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Национальный медицинский исследовательский центр кардиологии имени академика Е.И. Чазова<country>Россия</country></aff><aff xml:lang="en">E.I. Chazov National Medical Research Centre of Cardiology<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования “Кемеровский государственный медицинский университет” Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University” of the Ministry of Health of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>12</day><month>11</month><year>2025</year></pub-date><volume>14</volume><issue>5</issue><fpage>16</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ляпина И.Н., Кузьмина Ю.Е., Мартынюк Т.В., Дрень Е.В., Двадцатов И.В., Двадцатова П.Н., Аргунова Ю.А., Барбараш О.Л., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ляпина И.Н., Кузьмина Ю.Е., Мартынюк Т.В., Дрень Е.В., Двадцатов И.В., Двадцатова П.Н., Аргунова Ю.А., Барбараш О.Л.</copyright-holder><copyright-holder xml:lang="en">Lyapina I.N., Kuzmina Y.E., Martynyuk T.V., Dren' E.V., Dvadtsatov I.V., Dvadtsatova P.N., Argunova Y.A., Barbarash O.L.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1573">https://www.nii-kpssz.com/jour/article/view/1573</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения</p></sec><sec><title> </title><p> </p></sec><sec><title>Резюме</title><p>Резюме</p></sec><sec><title>Цель</title><p>Цель. Проанализировать периоперационное качество жизни и эмоциональное состояние пациентов с приобретенным пороком митрального клапана (ППМК), перенесших хирургическую коррекцию, а также оценить вклад предоперационной легочной гипертензии (ЛГ) в периоперационную динамику этих показателей.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование были включены 103 пациента с ППМК неинфекционного генеза, которые были госпитализированы для плановой операции на сердце. У 61,2% пациентов до операции была выявлена ЛГ. Анализ качества жизни (SF-36) и эмоционального состояния (HADS) проводился до операции и на 7-й день, через месяц и год после операции.</p></sec><sec><title>Результаты</title><p>Результаты. У пациентов с ППМК и предоперационной ЛГ в течение первого месяца после операции наблюдалась значительная положительная динамика качества жизни по многим параметрам. Однако пациенты без ЛГ были более компенсированы на исходном этапе, но демонстрировали функциональные ограничения в послеоперационном периоде. Установлено, что увеличение возраста пациента с ППМК на 1 год связано со снижением исходного уровня физической составляющей здоровья на B-коэффициент = –0,21 (р = 0,014). Наличие фибрилляции предсердий до коррекции ППМК было связано со снижением физической составляющей здоровья на 7-й день (B-коэффициент = –10,92; p = 0,03) и снижением психической составляющей здоровья на 30-й день после операции (B-коэффициент = –12,66; p = 0,006). Мужской пол ассоциируется с повышенным уровнем тревожности и депрессии во всех контрольных точках и более низким уровнем психического здоровья, чем у женщин с ППМК.</p></sec><sec><title>Заключение</title><p>Заключение. Были выявлены факторы, связанные с ухудшением качества жизни и эмоционального статуса как до, так и после хирургической коррекции приобретенного порока митрального клапана, такие как наличие фибрилляции предсердий до операции и мужской пол.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights</p></sec><sec><title> </title><p> </p></sec><sec><title>Summary</title><p>Summary</p></sec><sec><title>Aim</title><p>Aim. To analyze a perioperative quality of life and emotional state of patients with acquired mitral valve disease (AMVD) who underwent surgical correction, as well as to assess the contribution of preoperative pulmonary hypertension (PH) to the perioperative dynamics of these parameters.</p></sec><sec><title>Methods</title><p>Methods. The study included 103 patients with AMVD of noninfectious origin, who were hospitalized for elective cardiac surgery. 61.2% of patients had PH before surgery. Quality of life (SF-36) and emotional state (HADS) analysis were conducted before surgery and on day 7, one month and one year after surgery.</p></sec><sec><title>Results</title><p>Results. Patients with AMVD and preoperative PH showed significant positive dynamics in the quality of life in many parameters within the first month after surgery. However, patients without PH were more compensated at baseline and noted functional limitations in the postoperative period. It was found that an increase in the age of a patient with AMVD by 1 year is associated with a decrease in the initial level of the physical component of health by B-coefficient = –0.21 (p = 0.014). The presence of atrial fibrillation before the correction of the AMVD was associated with a decrease in the physical component of health on day 7 (B-coefficient = –10.92; p = 0.03) and decrease in the mental component of health on day 30 after surgery (B-coefficient = –12.66; p = 0.006). Male gender is associated with increased levels of anxiety and depression at all control points with lower level of mental health than women with AMVD.</p></sec><sec><title>Conclusion</title><p>Conclusion. Factors associated with a deterioration in quality of life and emotional status both before and after surgical correction of acquired mitral valve disease were identified as the presence of preoperative atrial fibrillation and male gender.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Пороки клапанов сердца</kwd><kwd>Хирургическая коррекция</kwd><kwd>Митральный клапан</kwd><kwd>Легочная гипертензия</kwd><kwd>Качество жизни</kwd><kwd>Тревога и депрессия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Valvular heart disease</kwd><kwd>Surgical correction</kwd><kwd>Mitral valve • Pulmonary hypertension</kwd><kwd>Quality of life</kwd><kwd>Anxiety and depression</kwd></kwd-group><funding-group xml:lang="en"><funding-statement>The study was carried out on the basis of the Federal State Budgetary Institution "Research Institute of Complex Issues of Cardiovascular Diseases", within the framework of the fundamental topic No. 0419-2022-0002 "Development of innovative models for managing the risk of developing diseases of the circulatory system, taking into account comorbidity, based on the study of fundamental, clinical, epidemiological mechanisms and organizational technologies of medical care in the industrial region of Siberia".</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Barbarash O.L., Odarenko Yu.N., Kondyukova N.V. 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