<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">kpccz-1679</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Кардиология. Патологическая физиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiology. Pathlogical physiology</subject></subj-group></article-categories><title-group><article-title>ХОЛЕСТЕРИНОВАЯ АТЕРОЭМБОЛИЯ КАК ПРИЧИНА НАРУШЕНИЯ РЕПЕРФУЗИИ МИОКАРДА ПРИ ЭНДОВАСКУЛЯРНОМ ВОССТАНОВЛЕНИИ КОРОНАРНОГО КРОВОТОКА (ОБЗОР ЛИТЕРАТУРЫ)</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2197-8756</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суковатых</surname><given-names>Борис Семенович</given-names></name></name-alternatives><email xlink:type="simple">SukovatykhBS@kursksmu.net</email></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0590-2225</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боломатов</surname><given-names>Николай Владимирович</given-names></name></name-alternatives><email xlink:type="simple">SukovatykhBS@kursksmu.net</email></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8964-5937</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сидоров</surname><given-names>Дмитрий Владимирович</given-names></name></name-alternatives><email xlink:type="simple">D7600S@yandex.ru</email></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1907-4395</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суковатых</surname><given-names>Михаил Борисович</given-names></name></name-alternatives><email xlink:type="simple">SukovatykhMB@kursksmu.net</email></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5039-5384</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьян</surname><given-names>Арсен Юрьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра оперативной хирургии и топографической анатомии</p><p>SPIN-код: 3090-4890</p></bio><email xlink:type="simple">arsgrigorian@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-2646-2364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Груздов</surname><given-names>Александр Юрьевич</given-names></name></name-alternatives><email xlink:type="simple">alexander.gruzdov@inbox.ru</email></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Курский государственный медицинский университет<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>02</day><month>03</month><year>2026</year></pub-date><volume>15</volume><issue>1</issue><fpage>72</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Суковатых Б.С., Боломатов Н.В., Сидоров Д.В., Суковатых М.Б., Григорьян А.Ю., Груздов А.Ю., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Суковатых Б.С., Боломатов Н.В., Сидоров Д.В., Суковатых М.Б., Григорьян А.Ю., Груздов А.Ю.</copyright-holder><copyright-holder xml:lang="en">Суковатых Б.С., Боломатов Н.В., Сидоров Д.В., Суковатых М.Б., Григорьян А.Ю., Груздов А.Ю.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1679">https://www.nii-kpssz.com/jour/article/view/1679</self-uri><abstract><p>В статье проанализированы данные отечественной и зарубежной литературы, раскрывающие проблему нарушений коронарного кровотока при эндоваскулярных вмешательствах. С современных позиций представлена роль различных факторов риска развития нарушения реперфузии миокарда. Описаны способы клинической и инструментальной диагностики феноменов замедленного и невосстановленного коронарного кровотока. Подчеркнута необходимость индивидуального подхода к применению лекарственных препаратов для купирования  коронарных нарушений. Акцентировано внимание на современных способах инструментальной профилактики холестериновой атероэмболии. Указано на необходимость исключения  рутинной тромбэктомии при чрескожных коронарных вмешательствах. </p></abstract><kwd-group xml:lang="ru"><kwd>чрескожное коронарное вмешательство</kwd><kwd>холестериновая атероэмболия</kwd><kwd>феномены замедленного и невосстановленного  коронарного кровотока</kwd><kwd>диагностика</kwd><kwd>профилактика</kwd><kwd>лечение</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ozkok A. Cholesterol-embolization syndrome: current perspectives. Vasc Health Risk Manag. 2019; 15: 209-220. doi: 10.2147/VHRM.S175150</mixed-citation><mixed-citation xml:lang="en">Ozkok A. Cholesterol-embolization syndrome: current perspectives. Vasc Health Risk Manag. 2019; 15: 209-220. doi: 10.2147/VHRM.S175150</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Pantea-Roșan L.R., Bungau S.G., Radu A.F., Pantea V.A., Moisi M.I., Vesa C.M., Behl T., Nechifor A.C., Babes E.E., Stoicescu M., Gitea D., Iovanovici D.C., Bustea C. A Narrative Review of the Classical and Modern Diagnostic Methods of the No-Reflow Phenomenon. Diagnostics (Basel). 2022; 12(4): 932. doi: 10.3390/diagnostics12040932</mixed-citation><mixed-citation xml:lang="en">Pantea-Roșan LR, Bungau SG, Radu AF, Pantea VA, Moisi MI, Vesa CM, Behl T, Nechifor AC, Babes EE, Stoicescu M, Gitea D, Iovanovici DC, Bustea C. A Narrative Review of the Classical and Modern Diagnostic Methods of the No-Reflow Phenomenon. Diagnostics (Basel). 2022; 12(4): 932. doi: 10.3390/diagnostics12040932</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Shahri B., Vojdanparast M. Coronary No-reflow Phenomenon: A Review of Therapeutic Pharmacological Agents. Razavi International Journal of Medicine. 2020; 8(1-4): e1002. doi: 10.30483/rijm.2020.254145.1002</mixed-citation><mixed-citation xml:lang="en">Shahri B, Vojdanparast M. Coronary No-reflow Phenomenon: A Review of Therapeutic Pharmacological Agents. Razavi International Journal of Medicine. 2020; 8(1-4): e1002. doi: 10.30483/rijm.2020.254145.1002</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Герасимов А.М., Терещенко А.С., Меркулов Е.В., Самко А.Н. Феномен невоcстановленного коронарного кровотока (no-reflow) в практике эндоваскулярного хирурга. Вестник рентгенологии и радиологии. 2014; (1): 51-55. doi: 10.20862/0042-4676-2014-0-1-51-55</mixed-citation><mixed-citation xml:lang="en">Gerasimov AM, Tereshchenko AS, Merkulov EV, Samko AN. No-reflow phenomenon in the practice of an endovascular surgeon. Journal of radiology and nuclear medicine. 2014;(1):51-55. (In Russ.) doi: 10.20862/0042-4676-2014-0-1-51-55</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Majno G., Ames A., Chaing J., Wright R.L. No reflow after cerebral ischemia. Lancet. 1967; 290(7515): 569-570. doi: 10.1016/S0140-6736(67)90552-1</mixed-citation><mixed-citation xml:lang="en">Majno G, Ames A, Chaing J, Wright RL. No reflow after cerebral ischemia. Lancet. 1967; 290(7515): 569-570. doi: 10.1016/S0140-6736(67)90552-1</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Халирахманов А.Ф., Газиев Э.А., Шарафеев А.З., Шарафутдинов Б.М. Развитие феномена «no-reflow» после чрескожных коронарных вмешательств: современные аспекты. Диагностическая и интервенционная радиология. 2019; 13(4): 57-66. doi: 10.25512/DIR.2019.13.4.06</mixed-citation><mixed-citation xml:lang="en">Khalirakhmanov AF, Gaziev EA, Sharafeev AZ, Sharafutdinov BM. Development of "no-reflow" phenomenon after percutaneous coronary interventions: current aspects. Diagnostic and Interventional Radiology. 2019; 13(4): 57-66. (In Russ) doi: 10.25512/DIR.2019.13.4.06</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Shah M., Mohsin M., Satti K.N. Predictors and in-hospital mortality of slow flow/no-reflow after percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Journal of Akhtar Saeed Medical &amp; Dental College. 2023; 5(03): 144-151. doi: 10.51127/JAMDCV5I3OA05</mixed-citation><mixed-citation xml:lang="en">Shah M, Mohsin M, Satti KN. Predictors and in-hospital mortality of slow flow/no-reflow after percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Journal of Akhtar Saeed Medical &amp; Dental College. 2023; 5(03): 144-151. doi: 10.51127/JAMDCV5I3OA05</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Avci E., Yildirim T., Aydin G., Kiris T., Dolapoglu A., Kadi H., Safak O., Bayata S. Combining clinical predictors to better predict for the no-reflow phenomenon. Eur Rev Med Pharmacol Sci. 2018; 22(15): 4987-4994. doi: 10.26355/eurrev_201808_15639</mixed-citation><mixed-citation xml:lang="en">Avci E, Yildirim T, Aydin G, Kiris T, Dolapoglu A, Kadi H, Safak O, Bayata S. Combining clinical predictors to better predict for the no-reflow phenomenon. Eur Rev Med Pharmacol Sci. 2018; 22(15): 4987-4994. doi: 10.26355/eurrev_201808_15639</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Savic L., Mrdovic I., Asanin M., Stankovic S., Lasica R., Krljanac G., Rajic D., Simic D. The Impact of Kidney Function on the Slow-Flow/No-Reflow Phenomenon in Patients Treated with Primary Percutaneous Coronary Intervention: Registry Analysis. J Interv Cardiol. 2022; 2022: 5815274. doi: 10.1155/2022/5815274</mixed-citation><mixed-citation xml:lang="en">Savic L, Mrdovic I, Asanin M, Stankovic S, Lasica R, Krljanac G, Rajic D, Simic D. The Impact of Kidney Function on the Slow-Flow/No-Reflow Phenomenon in Patients Treated with Primary Percutaneous Coronary Intervention: Registry Analysis. J Interv Cardiol. 2022; 2022: 5815274. doi: 10.1155/2022/5815274</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kai T., Oka S., Hoshino K., Watanabe K., Nakamura J., Abe M., Watanabe A. Renal Dysfunction as a Predictor of Slow-Flow/No-Reflow Phenomenon and Impaired ST Segment Resolution After Percutaneous Coronary Intervention in ST-Elevation Myocardial Infarction With Initial Thrombolysis in Myocardial Infarction Grade 0. Circ J. 2021; 85(10): 1770-1778. doi: 10.1253/circj.CJ-21-0221</mixed-citation><mixed-citation xml:lang="en">Kai T, Oka S, Hoshino K, Watanabe K, Nakamura J, Abe M, Watanabe A. Renal Dysfunction as a Predictor of Slow-Flow/No-Reflow Phenomenon and Impaired ST Segment Resolution After Percutaneous Coronary Intervention in ST-Elevation Myocardial Infarction With Initial Thrombolysis in Myocardial Infarction Grade 0. Circ J. 2021; 85(10): 1770-1778. doi: 10.1253/circj.CJ-21-0221</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hu X., Yang X., Li X., Li G., Zhou Y., Dong H. Elevated uric acid is related to the no-/slow-reflow phenomenon in STEMI undergoing primary PCI. Eur J Clin Invest. 2022; 52(4): e13719. doi: 10.1111/eci.13719</mixed-citation><mixed-citation xml:lang="en">Hu X, Yang X, Li X, Li G, Zhou Y, Dong H. Elevated uric acid is related to the no-/slow-reflow phenomenon in STEMI undergoing primary PCI. Eur J Clin Invest. 2022; 52(4): e13719. doi: 10.1111/eci.13719</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Somuncu M.U., Akgun T., Cakır M.O., Akgul F., Serbest N.G., Karakurt H., Can M., Demir A.R. The Elevated Soluble ST2 Predicts No-Reflow Phenomenon in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. J Atheroscler Thromb. 2019; 26(11): 970-978. doi: 10.5551/jat.48413</mixed-citation><mixed-citation xml:lang="en">Somuncu MU, Akgun T, Cakır MO, Akgul F, Serbest NG, Karakurt H, Can M, Demir AR. The Elevated Soluble ST2 Predicts No-Reflow Phenomenon in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. J Atheroscler Thromb. 2019; 26(11): 970-978. doi: 10.5551/jat.48413</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Q., Hu M., Ma S. Association of Soluble Suppression of Tumorigenicity with No-Reflow Phenomenon and Long-Term Prognosis in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome after Percutaneous Coronary Intervention. J Atheroscler Thromb. 2021; 28(12): 1289-1297. doi: 10.5551/jat.59832</mixed-citation><mixed-citation xml:lang="en">Zhang Q, Hu M, Ma S. Association of Soluble Suppression of Tumorigenicity with No-Reflow Phenomenon and Long-Term Prognosis in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome after Percutaneous Coronary Intervention. J Atheroscler Thromb. 2021; 28(12): 1289-1297. doi: 10.5551/jat.59832</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Sondergaard F.T., Beske R.P., Frydland M., Moller J.E., Helgestad O.K.L., Jensen L.O., Holmvang L., Goetze J.P., Engstrom T., Hassager C. Soluble ST2 in plasma is associated with post-procedural no-or-slow reflow after primary percutaneous coronary intervention in ST-elevation myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2023; 12(1): 48-52. doi: 10.1093/ehjacc/zuac146</mixed-citation><mixed-citation xml:lang="en">Sondergaard FT, Beske RP, Frydland M, Moller JE, Helgestad OKL, Jensen LO, Holmvang L, Goetze JP, Engstrom T, Hassager C. Soluble ST2 in plasma is associated with post-procedural no-or-slow reflow after primary percutaneous coronary intervention in ST-elevation myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2023; 12(1): 48-52. doi: 10.1093/ehjacc/zuac146</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Li Y., Liang X., Zhang W., Qiao X., Wang Z. The Clinical and Angiographic Outcomes of Postdilation after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome: A Systematic Review and Meta-Analysis. J Interv Cardiol. 2021; 2021: 6699812. doi: 10.1155/2021/6699812</mixed-citation><mixed-citation xml:lang="en">Li Y, Liang X, Zhang W, Qiao X, Wang Z. The Clinical and Angiographic Outcomes of Postdilation after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome: A Systematic Review and Meta-Analysis. J Interv Cardiol. 2021; 2021: 6699812. doi: 10.1155/2021/6699812</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Fajar J.K., Heriansyah T., Rohman M.S. The predictors of no reflow phenomenon after percutaneous coronary intervention in patients with ST elevation myocardial infarction: A meta-analysis. Indian Heart J. 2018; 70(3): S406-S418. doi: 10.1016/j.ihj.2018.01.032</mixed-citation><mixed-citation xml:lang="en">Fajar JK, Heriansyah T, Rohman MS. The predictors of no reflow phenomenon after percutaneous coronary intervention in patients with ST elevation myocardial infarction: A meta-analysis. Indian Heart J. 2018; 70(3): S406-S418. doi: 10.1016/j.ihj.2018.01.032</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta S., Gupta M.M. No reflow phenomenon in percutaneous coronary interventions in ST-segment elevation myocardial infarction. Indian Heart J. 2016; 68(4): 539-51. doi: 10.1016/j.ihj.2016.04.006</mixed-citation><mixed-citation xml:lang="en">Gupta S, Gupta MM. No reflow phenomenon in percutaneous coronary interventions in ST-segment elevation myocardial infarction. Indian Heart J. 2016; 68(4): 539-51. doi: 10.1016/j.ihj.2016.04.006</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Abtan J., Wiviott S.D., Sorbets E., Popovic B., Elbez Y., Mehta S.R., Sabatine M.S., Bode C., Pollack C.V., Cohen M., Moccetti T., Laanmets P., Faxon D., Okreglicki A., Ducrocq G., Steg P.G.; TAO investigators. Prevalence, clinical determinants and prognostic implications of coronary procedural complications of percutaneous coronary intervention in non-ST-segment elevation myocardial infarction: Insights from the contemporary multinational TAO trial. Arch Cardiovasc Dis. 2021; 114(3): 187-196. doi: 10.1016/j.acvd.2020.09.005</mixed-citation><mixed-citation xml:lang="en">Abtan J, Wiviott SD, Sorbets E, Popovic B, Elbez Y, Mehta SR, Sabatine MS, Bode C, Pollack CV, Cohen M, Moccetti T, Laanmets P, Faxon D, Okreglicki A, Ducrocq G, Steg PG; TAO investigators. Prevalence, clinical determinants and prognostic implications of coronary procedural complications of percutaneous coronary intervention in non-ST-segment elevation myocardial infarction: Insights from the contemporary multinational TAO trial. Arch Cardiovasc Dis. 2021; 114(3): 187-196. doi: 10.1016/j.acvd.2020.09.005</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Agrawal A., Ziccardi M.R., Witzke C., Palacios I., Rangaswami J. Cholesterol embolization syndrome: An under-recognized entity in cardiovascular interventions. J Interv Cardiol. 2018; 31(3): 407-415. doi: 10.1111/joic.12483</mixed-citation><mixed-citation xml:lang="en">Agrawal A, Ziccardi MR, Witzke C, Palacios I, Rangaswami J. Cholesterol embolization syndrome: An under-recognized entity in cardiovascular interventions. J Interv Cardiol. 2018; 31(3): 407-415. doi: 10.1111/joic.12483</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Alief W., Mukti C.N., Henry S. Cholesterol crystal embolism: Unraveling its impact on atherosclerotic cardiovascular diseases. Journal of Medicine, Surgery, and Public Health. 2024; 3: 100102. DOI: 10.1016/j.glmedi.2024.100102</mixed-citation><mixed-citation xml:lang="en">Alief W, Mukti CN, Henry S. Cholesterol crystal embolism: Unraveling its impact on atherosclerotic cardiovascular diseases. Journal of Medicine, Surgery, and Public Health. 2024; 3: 100102. DOI: 10.1016/j.glmedi.2024.100102</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Sinha S.K., Kumar P., Sharma A.K., Razi M., Pandey U., Sachan M., Shukla P., Aggarwal P., Jha M.J., Thakur R., Krishna V. Perforated balloon technique mediated intracoronary delivery of nicorandil to treat coronary no-reflow phenomenon: a novel pharmacological solution to precarious situation. Am J Cardiovasc Dis. 2021; 11(5): 544-554.</mixed-citation><mixed-citation xml:lang="en">Sinha SK, Kumar P, Sharma AK, Razi M, Pandey U, Sachan M, Shukla P, Aggarwal P, Jha MJ, Thakur R, Krishna V. Perforated balloon technique mediated intracoronary delivery of nicorandil to treat coronary no-reflow phenomenon: a novel pharmacological solution to precarious situation. Am J Cardiovasc Dis. 2021; 11(5): 544-554.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Allencherril J., Jneid H., Atar D., Alam M., Levine G., Kloner R.A., Birnbaum Y. Pathophysiology, Diagnosis, and Management of the No-Reflow Phenomenon. Cardiovasc Drugs Ther. 2019; 33(5): 589-597. doi: 10.1007/s10557-019-06901-0</mixed-citation><mixed-citation xml:lang="en">Allencherril J, Jneid H, Atar D, Alam M, Levine G, Kloner RA, Birnbaum Y. Pathophysiology, Diagnosis, and Management of the No-Reflow Phenomenon. Cardiovasc Drugs Ther. 2019; 33(5): 589-597. doi: 10.1007/s10557-019-06901-0</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Hu X., Wang W., Ye J., Lin Y., Yu B., Zhou L., Zhou Y., Dong H. Effect of GP IIb/IIIa inhibitor duration on the clinical prognosis of primary percutaneous coronary intervention in ST-segment elevation myocardial infarction with no-/slow-reflow phenomenon. Biomed Pharmacother. 2021; 143: 112196. doi: 10.1016/j.biopha.2021.112196</mixed-citation><mixed-citation xml:lang="en">Hu X, Wang W, Ye J, Lin Y, Yu B, Zhou L, Zhou Y, Dong H. Effect of GP IIb/IIIa inhibitor duration on the clinical prognosis of primary percutaneous coronary intervention in ST-segment elevation myocardial infarction with no-/slow-reflow phenomenon. Biomed Pharmacother. 2021; 143: 112196. doi: 10.1016/j.biopha.2021.112196</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">De Luca G., Suryapranata H., Stone G.W., Antoniucci D., Tcheng J.E., Neumann F.J., Van de Werf F., Antman E.M., Topol E.J. Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized trials. JAMA. 2005; 293(14): 1759-1765. doi: 10.1001/jama.293.14.1759</mixed-citation><mixed-citation xml:lang="en">De Luca G, Suryapranata H, Stone GW, Antoniucci D, Tcheng JE, Neumann FJ, Van de Werf F, Antman EM, Topol EJ. Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized trials. JAMA. 2005; 293(14): 1759-1765. doi: 10.1001/jama.293.14.1759</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Petronio A.S., Rovai D., Musumeci G., Baglini R., Nardi C., Limbruno U., Palagi C., Volterrani D., Mariani M. Effects of abciximab on microvascular integrity and left ventricular functional recovery in patients with acute infarction treated by primary coronary angioplasty. Eur Heart J. 2003; 24(1): 67-76. doi: 10.1016/s0195-668x(02)00324-1</mixed-citation><mixed-citation xml:lang="en">Petronio AS, Rovai D, Musumeci G, Baglini R, Nardi C, Limbruno U, Palagi C, Volterrani D, Mariani M. Effects of abciximab on microvascular integrity and left ventricular functional recovery in patients with acute infarction treated by primary coronary angioplasty. Eur Heart J. 2003; 24(1): 67-76. doi: 10.1016/s0195-668x(02)00324-1</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Simoons M.L., GUSTO IV-ACS Investigators. Effect of glycoprotein IIb/IIIa receptor blocker abciximab on outcome in patients with acute coronary syndromes without early coronary revascularisation: the GUSTO IV-ACS randomised trial. The Lancet. 2001; 357(9272): 1915-24. DOI: 10.1016/S0140-6736(00)05060-1</mixed-citation><mixed-citation xml:lang="en">Simoons ML; GUSTO IV-ACS Investigators. Effect of glycoprotein IIb/IIIa receptor blocker abciximab on outcome in patients with acute coronary syndromes without early coronary revascularisation: the GUSTO IV-ACS randomised trial. The Lancet. 2001; 357(9272): 1915-24. doi: 10.1016/S0140-6736(00)05060-1</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Сухинина Т.С., Певзнер Д.В., Мазуров А.В., Власик Т.Н., Соловьёва Н.Г., Кострица Н.С., Шахнович Р.М., Явелов И.С. Роль блокаторов гликопротеина IIb / IIIa рецепторов тромбоцитов при современном лечении больных с острым коронарным синдромом. Кардиология. 2022; 62(4): 64-72. doi: 10.18087/cardio.2022.4.n2020</mixed-citation><mixed-citation xml:lang="en">Sukhinina TS, Pevzner DV, Mazurov AV, Vlasik TN, Solovieva NG, Kostritca NS, Shakhnovich RM, Yavelov IS. The role of platelet glycoprotein IIb / IIIa inhibitors in current treatment of acute coronary syndrome. Kardiologiia. 2022; 62(4): 64-72. (In Russ) doi: 10.18087/cardio.2022.4.n2020</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Callichurn K., Simard P., De Marco C., Jamali P., Saada Y., Matteau A., Schampaert E., Mansour S., Hatem R., Potter B.J. A dual-center analysis of conservative versus liberal glycoprotein IIb-IIIa antagonist strategies in the treatment of ST-elevation myocardial infarction. Sci Rep. 2024; 14(1): 15003. doi: 10.1038/s41598-024-64652-x</mixed-citation><mixed-citation xml:lang="en">Callichurn K, Simard P, De Marco C, Jamali P, Saada Y, Matteau A, Schampaert E, Mansour S, Hatem R, Potter BJ. A dual-center analysis of conservative versus liberal glycoprotein IIb-IIIa antagonist strategies in the treatment of ST-elevation myocardial infarction. Sci Rep. 2024; 14(1): 15003. doi: 10.1038/s41598-024-64652-x</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Bocchino P.P., Angelini F., Gallone G., Frea S., De Ferrari G.M. The cardiovascular safety of sodium nitroprusside in acute heart failure. Expert Opin Drug Saf. 2024; 23(6): 663-666. doi: 10.1080/14740338.2024.2348570</mixed-citation><mixed-citation xml:lang="en">Bocchino PP, Angelini F, Gallone G, Frea S, De Ferrari GM. The cardiovascular safety of sodium nitroprusside in acute heart failure. Expert Opin Drug Saf. 2024; 23(6): 663-666. doi: 10.1080/14740338.2024.2348570</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Berg R., Buhari C. Treating and preventing no reflow in the cardiac catheterization laboratory. Current cardiology reviews. 2012; 8(3): 209-214.</mixed-citation><mixed-citation xml:lang="en">Berg R, Buhari C. Treating and preventing no reflow in the cardiac catheterization laboratory. Current cardiology reviews. 2012; 8(3): 209-214.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Procopio M.C., Lauro R., Nasso C., Carerj S., Squadrito F., Bitto A., Di Bella G., Micari A., Irrera N., Costa F. Role of Adenosine and Purinergic Receptors in Myocardial Infarction: Focus on Different Signal Transduction Pathways. Biomedicines. 2021; 9(2): 204. doi: 10.3390/biomedicines9020204</mixed-citation><mixed-citation xml:lang="en">Procopio MC, Lauro R, Nasso C, Carerj S, Squadrito F, Bitto A, Di Bella G, Micari A, Irrera N, Costa F. Role of Adenosine and Purinergic Receptors in Myocardial Infarction: Focus on Different Signal Transduction Pathways. Biomedicines. 2021; 9(2): 204. doi: 10.3390/biomedicines9020204</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Laborante R., Bianchini E., Restivo A., Ciliberti G., Galli M., Vergallo R., Rodolico D., Zito A., Princi G., Leone A.M., Aurigemma C., Romagnoli E., Montone R.A., Burzotta F., Trani C., Crea F., D'Amario D. Adenosine as adjunctive therapy in acute coronary syndrome: a meta-analysis of randomized controlled trials. Eur Heart J Cardiovasc Pharmacother. 2023; 9(2): 173-182. doi: 10.1093/ehjcvp/pvac069</mixed-citation><mixed-citation xml:lang="en">Laborante R, Bianchini E, Restivo A, Ciliberti G, Galli M, Vergallo R, Rodolico D, Zito A, Princi G, Leone AM, Aurigemma C, Romagnoli E, Montone RA, Burzotta F, Trani C, Crea F, D'Amario D. Adenosine as adjunctive therapy in acute coronary syndrome: a meta-analysis of randomized controlled trials. Eur Heart J Cardiovasc Pharmacother. 2023; 9(2): 173-182. doi: 10.1093/ehjcvp/pvac069</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Grancini L., Diana D., Centola A., Monizzi G., Mastrangelo A., Olivares P., Montorsi P., Alushi B., Bartorelli A.L., Galassi A.R. The SALINE Technique for the Treatment of the No-Reflow Phenomenon during Percutaneous Coronary Intervention in STEMI. J Clin Med. 2023; 12(6): 2405. doi: 10.3390/jcm12062405</mixed-citation><mixed-citation xml:lang="en">Grancini L, Diana D, Centola A, Monizzi G, Mastrangelo A, Olivares P, Montorsi P, Alushi B, Bartorelli AL, Galassi AR. The SALINE Technique for the Treatment of the No-Reflow Phenomenon during Percutaneous Coronary Intervention in STEMI. J Clin Med. 2023; 12(6): 2405. doi: 10.3390/jcm12062405</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Egred M., Bagnall A., Spyridopoulos I., Purcell I.F., Das R., Palmer N., Grech E.D., Jain A., Stone G.W., Nijveldt R., McAndrew T., Zaman A. Effect of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size in anterior STEMI: PiCSO in ACS study. Int J Cardiol Heart Vasc. 2020; 28: 100526. doi: 10.1016/j.ijcha.2020.100526</mixed-citation><mixed-citation xml:lang="en">Egred M, Bagnall A, Spyridopoulos I, Purcell IF, Das R, Palmer N, Grech ED, Jain A, Stone GW, Nijveldt R, McAndrew T, Zaman A. Effect of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size in anterior STEMI: PiCSO in ACS study. Int J Cardiol Heart Vasc. 2020; 28: 100526. doi: 10.1016/j.ijcha.2020.100526</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson C.M., Ajmi I., von Koenig C.L., Turco M.A., Stone G.W. Pressure-Controlled Intermittent Coronary Sinus Occlusion: A Novel Approach to Improve Microvascular Flow and Reduce Infarct Size in STEMI. Cardiovasc Revasc Med. 2022; 45: 9-14. doi: 10.1016/j.carrev.2022.07.007</mixed-citation><mixed-citation xml:lang="en">Gibson CM, Ajmi I, von Koenig CL, Turco MA, Stone GW. Pressure-Controlled Intermittent Coronary Sinus Occlusion: A Novel Approach to Improve Microvascular Flow and Reduce Infarct Size in STEMI. Cardiovasc Revasc Med. 2022; 45: 9-14. doi: 10.1016/j.carrev.2022.07.007</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Texakalidis P., Letsos A., Kokkinidis D.G., Schizas D., Karaolanis G., Giannopoulos S., Giannopoulos S., Economopoulos K.P., Bakoyannis C. Proximal embolic protection versus distal filter protection versus combined protection in carotid artery stenting: A systematic review and meta-analysis. Cardiovasc Revasc Med. 2018; 19(5 Pt A): 545-552. doi: 10.1016/j.carrev.2017.12.010</mixed-citation><mixed-citation xml:lang="en">Texakalidis P, Letsos A, Kokkinidis DG, Schizas D, Karaolanis G, Giannopoulos S, Giannopoulos S, Economopoulos KP, Bakoyannis C. Proximal embolic protection versus distal filter protection versus combined protection in carotid artery stenting: A systematic review and meta-analysis. Cardiovasc Revasc Med. 2018; 19(5 Pt A): 545-552. doi: 10.1016/j.carrev.2017.12.010</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Giannopoulos S., Sagris M., Giannopoulos S., Tzoumas A., Kokkinidis D.G., Texakalidis P., Koutsias G., Volteas P., Jing L., Malgor R.D. Embolic protection devices for carotid artery stenting: A network meta-analysis. Vascular. 2024; 32(2): 447-457. doi: 10.1177/17085381221140616</mixed-citation><mixed-citation xml:lang="en">Giannopoulos S, Sagris M, Giannopoulos S, Tzoumas A, Kokkinidis DG, Texakalidis P, Koutsias G, Volteas P, Jing L, Malgor RD. Embolic protection devices for carotid artery stenting: A network meta-analysis. Vascular. 2024; 32(2): 447-457. doi: 10.1177/17085381221140616</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Celik M., Yuksel U.C., Yalcinkaya E., Gokoglan Y., Iyisoy A. Conservative treatment of iatrogenic left main coronary artery dissection: report of two cases. Cardiovasc Diagn Ther. 2013; 3(4): 244-246. doi: 10.3978/j.issn.2223-3652.2013.10.04</mixed-citation><mixed-citation xml:lang="en">Celik M, Yuksel UC, Yalcinkaya E, Gokoglan Y, Iyisoy A. Conservative treatment of iatrogenic left main coronary artery dissection: report of two cases. Cardiovasc Diagn Ther. 2013; 3(4): 244-246. doi: 10.3978/j.issn.2223-3652.2013.10.04</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">De Luca L., Sardella G., Davidson C.J., De Persio G., Beraldi M., Tommasone T., Mancone M., Nguyen B.L., Agati L., Gheorghiade M., Fedele F. Impact of intracoronary aspiration thrombectomy during primary angioplasty on left ventricular remodelling in patients with anterior ST elevation myocardial infarction. Heart. 2006; 92(7): 951-957. doi: 10.1136/hrt.2005.074716</mixed-citation><mixed-citation xml:lang="en">De Luca L, Sardella G, Davidson CJ, De Persio G, Beraldi M, Tommasone T, Mancone M, Nguyen BL, Agati L, Gheorghiade M, Fedele F. Impact of intracoronary aspiration thrombectomy during primary angioplasty on left ventricular remodelling in patients with anterior ST elevation myocardial infarction. Heart. 2006; 92(7): 951-957. doi: 10.1136/hrt.2005.074716</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Satti Z., Omari M., Bawamia B., Cartlidge T., Egred M., Farag M., Alkhalil M. The Use of Thrombectomy during Primary Percutaneous Coronary Intervention: Resurrecting an Old Concept in Contemporary Practice. J Clin Med. 2024; 13(8): 2291. doi: 10.3390/jcm13082291</mixed-citation><mixed-citation xml:lang="en">Satti Z, Omari M, Bawamia B, Cartlidge T, Egred M, Farag M, Alkhalil M. The Use of Thrombectomy during Primary Percutaneous Coronary Intervention: Resurrecting an Old Concept in Contemporary Practice. J Clin Med. 2024; 13(8): 2291. doi: 10.3390/jcm13082291</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou L., Hu X., Zhang H., Lu H., Lin Y., Wang W., Yu B., Liang W., Zhou Y., Li G., Dong H. Effects of atorvastatin and rosuvastatin on dysfunctional coronary circulation in patients with ST-segment elevation myocardial infarction. J Int Med Res. 2023; 51(6): 3000605231182547. doi: 10.1177/03000605231182547</mixed-citation><mixed-citation xml:lang="en">Zhou L, Hu X, Zhang H, Lu H, Lin Y, Wang W, Yu B, Liang W, Zhou Y, Li G, Dong H. Effects of atorvastatin and rosuvastatin on dysfunctional coronary circulation in patients with ST-segment elevation myocardial infarction. J Int Med Res. 2023; 51(6): 3000605231182547. doi: 10.1177/03000605231182547</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Михайлова З.Д., Климкин П.Ф. Синдром холестериновой атероэмболии: современное состояние проблемы. Архивъ внутренней медицины. 2020; 10(4): 272-280. doi: 10.20514/2226-6704-2020-10-4-272-280</mixed-citation><mixed-citation xml:lang="en">Mikhailova ZD, Klimkin PF. Cholesterol Atheroembolism Syndrome: Current State of the Problem. The Russian Archives of Internal Medicine. 2020; 10(4): 272-280. (In Russ) doi: 10.20514/2226-6704-2020-10-4-272-280</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
