kpcczКомплексные проблемы сердечно-сосудистых заболеванийComplex Issues of Cardiovascular Diseases2306-12782587-9537Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”10.17802/2306-1278-2025-14-3-192-202kpccz-1698Research ArticleОНЛАЙН. АНАЛИТИЧЕСКИЙ ОБЗОР. Трансплантология и искусственные органыНЕОРГАНИЧЕСКОЕ ПОКРЫТИЕ ИМПЛАНТОВ В СЕРДЕЧНО-СОСУДИСТОЙ ХИРУРГИИ: ТЕКУЩЕЕ СОСТОЯНИЕ ПРОБЛЕМЫ (ОБЗОР ЛИТЕРАТУРЫ)INORGANIC COATINGS FOR IMPLANTS IN CARDIOVASCULAR SURGERY: CURRENT STATE OF THE ART (A REVIEW ARTICLE)https://orcid.org/0000-0002-2617-2447ПротопоповАндрей ВладимировичProtopopovAndrey V.

аспирант, младший научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

Postgraduate Student, Junior Researcher, Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation

andrew-uss@yandex.ruhttps://orcid.org/0000-0001-7976-596XЖульковМаксим ОлеговичZhulkovMaxim O.

кандидат медицинских наук научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

MD, PhD, Researcher, Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation

medicus-maligna@mail.ruhttps://orcid.org/0000-0002-9940-3541СиротаДмитрий АндреевичSirotaDmitry A.

доктор медицинских наук заведующий научно-исследовательским отделом хирургии аорты, коронарных и периферических артерий института патологии кровообращения федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация; доцент кафедры сердечно-сосудистой хирургии факультета повышения квалификации и профессиональной переподготовки федерального государственного бюджетного образовательного учреждения высшего образования «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации Российской Федерации, Новосибирск, Российская Федерация

MD, PhD, Head of the Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation; Associate Professor, Department of Cardiovascular Surgery, Faculty of Advanced Training and Professional Retraining, Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian Federation, Novosibirsk, Russian Federation

d_sirota@meshalkin.ruhttps://orcid.org/0009-0000-2435-9868СмирновЯрослав МаксимовичSmirnovYaroslav M.

медицинский брат-анестезист отделения анестезиологии и реанимации для взрослого населения федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация; студент лечебного факультета Института медицины и психологии В. Зельмана федерального государственного автономного образовательного учреждения высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск, Российская Федерация

Anesthesia Nurse, Department of Anesthesiology and Intensive Care for Adult Patients, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation; Medical Student, Faculty of Medicine, V. Zelman Institute of Medicine and Psychology, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk National Research State University”, Novosibirsk, Russian Federation

y.smirnov@g.nsu.ruhttps://orcid.org/0000-0001-6013-0200ГренадёровАлександр СергеевичGrenadyorovAlexander S.

доктор технических наук старший научный сотрудник лаборатории прикладной электроники, заместитель директора по научной работе федерального государственного бюджетного учреждения науки «Институт сильноточной электроники» Сибирского отделения Российской академии наук, Томск, Российская Федерация

PhD, Senior Researcher, Laboratory of Applied Electronics, Deputy Director for Research, Federal State Budgetary Institution of Science “Institute of High Current Electronics” of the Siberian Branch of the Russian Academy of Sciences, Tomsk, Russian Federation

1712sasha@mail.ruhttps://orcid.org/0000-0002-4752-988XСуровцеваМария АнатольевнаSurovtsevaMaria A.

кандидат медицинских наук лаборант лаборатории экспериментальной хирургии и морфологии института экспериментальной биологии и медицины федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

MD, PhD, Laboratory Assistant, Laboratory of Experimental Surgery and Morphology, Institute of Experimental Biology and Medicine, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation

mfelde@ngs.ruФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian FederationRussian FederationФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации; Федеральное государственное бюджетное образовательное учреждение высшего образования «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation; Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian FederationRussian FederationФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации; Федеральное государственное автономное образовательное учреждение высшего образования «Новосибирский национальный исследовательский государственный университет»РоссияFederal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation; Federal State Autonomous Educational Institution of Higher Education “Novosibirsk National Research State University”Russian FederationФедеральное государственное бюджетное учреждение науки «Институт сильноточной электроники» Сибирского отделения Российской академии наукРоссияFederal State Budgetary Institution of Science “Institute of High Current Electronics” of the Siberian Branch of the Russian Academy of SciencesRussian Federation202501072025143192202Copyright © Протопопов А.В., Жульков М.О., Сирота Д.А., Смирнов Я.М., Гренадёров А.С., Суровцева М.А., 20252025Протопопов А.В., Жульков М.О., Сирота Д.А., Смирнов Я.М., Гренадёров А.С., Суровцева М.А.Protopopov A.V., Zhulkov M.O., Sirota D.A., Smirnov Y.M., Grenadyorov A.S., Surovtseva M.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nii-kpssz.com/jour/article/view/1698Основные положения

Основные положения

 

 

Резюме

Резюме

Сердечно-сосудистые импланты, такие как стенты, клапаны и сосудистые протезы, требуют повышения долговечности и биосовместимости. В данном обзоре рассматриваются современные неорганические покрытия, включая нитрид титана, оксиды металлов и алмазоподобные углеродные покрытия, которые способны улучшать гемосовместимость имплантов. Особое внимание уделяется их влиянию на предотвращение тромбоза, рестеноза и кальцификации. Анализируются экспериментальные и клинические данные, подтверждающие эффективность этих покрытий.

Highlights

Highlights

 

 

Abstract

Abstract

Cardiovascular implants such as stents, valves, and vascular prostheses require continuous improvement to enhance their durability and biocompatibility. This review examines contemporary inorganic coatings, including titanium nitride, metal oxides, and diamond-like carbon coatings, which demonstrate potential for improving implant hemocompatibility. Particular focus is given to their role in preventing thrombosis, restenosis, and calcification. The paper analyzes both experimental and clinical data supporting the efficacy of these coatings.

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The authors declare that there are no conflicts of interest present.