kpcczКомплексные проблемы сердечно-сосудистых заболеванийComplex Issues of Cardiovascular Diseases2306-12782587-9537Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”10.17802/2306-1278-2025-14-5-256-272kpccz-1732Research ArticleОНЛАЙН. АНАЛИТИЧЕСКИЙ ОБЗОР. Сердечно-сосудистая хирургия. Трансплантология и искусственные органы.ТЕХНИЧЕСКИЕ АСПЕКТЫ РАЗРАБОТКИ ПОЛНОСТЬЮ ИСКУССТВЕННОГО СЕРДЦАTECHNICAL ASPECTS OF TOTAL ARTIFICIAL HEART DEVELOPMENThttps://orcid.org/0000-0003-3961-4993ПриходькоЮрий МихайловичPrikhodkoYurii M.

кандидат технических наук старший научный сотрудник федерального государственного бюджетного учреждения науки Институт теоретической и прикладной механики им. С.А. Христиановича Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация

PhD, Senior Researcher, Khristianovich Institute of Theoretical and Applied Mechanics of the Siberian Branch of the RAS, Novosibirsk, Russian Federation

prih@itam.nsc.ruhttps://orcid.org/0000-0003-3761-5212МедведевАлексей ЕлизаровичMedvedevAlexey E.

доктор физико-математических наук главный научный сотрудник федерального государственного бюджетного учреждения науки Институт теоретической и прикладной механики им. С.А. Христиановича Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация

Dr. Sci. (Phys.-Math.), PhD, Chief Researcher, Khristianovich Institute of Theoretical and Applied Mechanics of the Siberian Branch of the RAS, Novosibirsk, Russian Federation

medvedev@itam.nsc.ruhttps://orcid.org/0000-0002-2811-0143ФоминВасилий МихайловичFominVasilii M.

профессор, доктор физико-математических наук, академик РАН научный руководитель института, заведующий лабораторией федерального государственного бюджетного учреждения науки Институт теоретической и прикладной механики им. С.А. Христиановича Сибирского отделения Российской академии наук, Новосибирск, Российская Федерация

Professor, Dr. Sci. (Phys.-Math.), Academician of the Russian Academy of Sciences (RAS), Scientific Director, Head of Laboratory Khristianovich Institute of Theoretical and Applied Mechanics of the Siberian Branch of the RAS, Novosibirsk, Russian Federation

fomin@itam.nsc.ruhttps://orcid.org/0000-0001-7976-596XЖульковМаксим ОлеговичZhulkovMaxim O.

кандидат медицинских наук научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения, врач – сердечно-сосудистый хирург кардиохирургического отделения № 2 федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

MD, PhD, Researcher, Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Healthcare of Russian Federation, Novosibirsk, Russian Federation

medicus-maligna@mail.ruhttps://orcid.org/0000-0002-9940-3541СиротаДмитрий АндреевичSirotaDmitry A.

доктор медицинских наук заведующий научно-исследовательским отделом хирургии аорты, коронарных и периферических артерий института патологии кровообращения, врач – сердечно-сосудистый хирург кардиохирургического отделения № 2 федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация; доцент кафедры сердечно-сосудистой хирургии факультета повышения квалификации и профессиональной переподготовки федерального государственного бюджетного образовательного учреждения высшего образования «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

MD, PhD, Head of the Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Adult Cardiac Surgery Department № 2, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Healthcare of Russian Federation, Novosibirsk, Russian Federation; Associate Professor, Department of Cardiovascular Surgery, Faculty of Advanced Training and Professional Retraining, Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian Federation, Novosibirsk, Russian Federation

d_sirota@meshalkin.ruhttps://orcid.org/0000-0002-2617-2447ПротопоповАндрей ВладимировичProtopopovAndrey V.

аспирант, младший научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения, врач – сердечно-сосудистый хирург кардиохирургического отделения № 2 федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

Postgraduate Student, Junior Researcher, Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Adult Cardiac Surgery Department № 2, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Healthcare of Russian Federation, Novosibirsk, Russian Federation

andrew-uss@yandex.ruhttps://orcid.org/0000-0001-9818-8678ЧернявскийАлександр МихайловичChernyavskiyAleksandr M.

член-корреспондент РАН, доктор медицинских наук, профессор генеральный директор федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация; заведующий кафедры сердечно-сосудистой хирургии федерального государственного бюджетного образовательного учреждения высшего образования «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации, Новосибирск, Российская Федерация

PhD, MD, Corresponding Member of the Russian Academy of Sciences, Professor, General Director of the Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Healthcare of Russian Federation, Novosibirsk, Russian Federation; Head of the Department of Cardiovascular Surgery at the Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian Federation, Novosibirsk, Russian Federation

amchern@mail.ruФедеральное государственное бюджетное учреждение науки Институт теоретической и прикладной механики им. С.А. Христиановича Сибирского отделения Российской академии наукРоссияKhristianovich Institute of Theoretical and Applied Mechanics of the Siberian Branch of the RASRussian FederationФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Healthcare of Russian FederationRussian FederationФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации; Федеральное государственное бюджетное образовательное учреждение высшего образования «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации Российской ФедерацииРоссияFederal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Healthcare of Russian Federation; Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian FederationRussian Federation202512112025145256272Copyright © Приходько Ю.М., Медведев А.Е., Фомин В.М., Жульков М.О., Сирота Д.А., Протопопов А.В., Чернявский А.М., 20252025Приходько Ю.М., Медведев А.Е., Фомин В.М., Жульков М.О., Сирота Д.А., Протопопов А.В., Чернявский А.М.Prikhodko Y.M., Medvedev A.E., Fomin V.M., Zhulkov M.O., Sirota D.A., Protopopov A.V., Chernyavskiy A.M.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nii-kpssz.com/jour/article/view/1732Основные положения

Основные положения:

 

 

Резюме

Резюме

В статье рассматриваются критически важные инженерные аспекты: проектирование миниатюрных, высоконадежных насосных систем (роторных/пульсирующих); разработка исключительно биосовместимых материалов, предотвращающих тромбоз и кальцификацию; создание эффективных систем управления кровотоком с автономной адаптацией под потребности пациента; интеграция перспективных источников энергии и систем беспроводной передачи. Особое внимание уделяется минимизации гемолиза и достижению гемодинамической совместимости.

Highlights

Highlights

 

 

Abstract

Abstract

The article examines critical engineering aspects: the design of miniature, highly reliable pump systems (rotary/pulsatile); the development of exceptionally biocompatible materials preventing thrombosis and calcification; the creation of efficient blood flow control systems with autonomous adaptation to patient needs; and the integration of advanced energy sources and wireless transmission systems. Particular attention is paid to minimizing hemolysis and achieving hemodynamic compatibility.

Полностью искусственное сердцеГемодинамикаLVADЛево- и правожелудочковая поддержка кровообращенияСердечная недостаточностьTotal artificial heartHemodynamicsLVADLeft and right ventricular circulatory supportHeart failureАвторы заявляют об отсутствии финансирования исследования.ReferencesAlexander Eskandary F, Kohl M, Dunkler D, Aliabadi A, Grömmer M, Schiferer A, et al. Lack of donor and recipient age interaction in cardiac transplantation. Journal of Heart and Lung Transplantation 2014;33:629–35. https://doi.org/10.1016/j.healun.2014.02.005.Alexander Eskandary F, Kohl M, Dunkler D, Aliabadi A, Grömmer M, Schiferer A, et al. Lack of donor and recipient age interaction in cardiac transplantation. Journal of Heart and Lung Transplantation 2014;33:629–35. https://doi.org/10.1016/j.healun.2014.02.005.Polyakov DS, Fomin I V., Belenkov YN, Mareev VY, Ageev FT, Artemyeva EG. Chronic heart failure in the Russian Federation: what has changed over 20 years of follow-up? 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The authors declare that there are no conflicts of interest present.