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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2025-14-6-236-248</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-1812</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОНЛАЙН. АНАЛИТИЧЕСКИЙ ОБЗОР. Кардиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ONLINE. REVIEW. CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>ОСТРАЯ СЕРДЕЧНАЯ НЕДОСТАТОЧНОСТЬ И ДЕКОМПЕНСАЦИЯ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ: РОЛЬ МУЛЬТИМОРБИДНОСТИ (ОБЗОР ЛИТЕРАТУРЫ)</article-title><trans-title-group xml:lang="en"><trans-title>ACUTE HEART FAILURE AND DECOMPENSATED HEART FAILURE: THE IMPORTANCE OF MULTIMORBIDITY (LITERATURE REVIEW)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4771-484X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Печерина</surname><given-names>Тамара Борзалиевна</given-names></name><name name-style="western" xml:lang="en"><surname>Pecherina</surname><given-names>Tamara B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинский наук, доцент главный врач, заведующая лабораторией патологии миокарда и трансплантации сердца отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD in Medical Sciences, MD, Associate Professor, Chief Physician, Head of the Laboratory of Myocardial Pathology and Heart Transplantation, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">tb.pechorina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7604-5481</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синькова</surname><given-names>Маргарита Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Sinkova</surname><given-names>Margarita N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент доцент кафедры последипломной подготовки и сестринского дела федерального государственного бюджетного образовательного учреждения высшего образования «Кемеровский государственный медицинский университет» Министерства здравоохранения Российской Федерации, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD in Medical Sciences, MD, Associate Professor, Associate Professor at the Department of Postgraduate Training and Nursing, Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University” of the Ministry of Healthcare of the Russian Federation, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">margov@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6288-1267</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусельникова</surname><given-names>Юлия Игоревна</given-names></name><name name-style="western" xml:lang="en"><surname>Guselnikova</surname><given-names>Yulia I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант по специальности «кардиология», лаборант-исследователь лаборатории патологии миокарда и трансплантации сердца отдела хирургии сердца и сосудов федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>Postgraduate Student (Cardiology), Research Assistant at the Laboratory of Myocardial Pathology and Heart Transplantation, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation</p></bio><email xlink:type="simple">guselnikova.2881@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4642-3610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>Ольга Леонидовна</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>Olga L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>академик РАН, доктор медицинских наук, профессор директор федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», Кемерово, Российская Федерация; заведующий кафедрой кардиологии и сердечно-сосудистой хирургии федерального государственного бюджетного образовательного учреждения высшего образования «Кемеровский государственный медицинский университет» Министерства здравоохранения Российской Федерации, Кемерово, Российская Федерация</p></bio><bio xml:lang="en"><p>PhD in Medical Sciences, MD, Professor, Academician of the Russian Academy of Sciences, Director of the Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation; Head of the Department of Cardiology and Cardiovascular Surgery, Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University” of the Ministry of Healthcare of the Russian Federation, Kemerovo, Russian Federation</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Кемеровский государственный медицинский университет» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University” of the Ministry of Healthcare of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»; &#13;
Федеральное государственное бюджетное образовательное учреждение высшего образования «Кемеровский государственный медицинский университет» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”; &#13;
Federal State Budgetary Educational Institution of Higher Education “Kemerovo State Medical University” of the Ministry of Healthcare of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2025</year></pub-date><volume>14</volume><issue>6</issue><fpage>236</fpage><lpage>248</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Печерина Т.Б., Синькова М.Н., Гусельникова Ю.И., Барбараш О.Л., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Печерина Т.Б., Синькова М.Н., Гусельникова Ю.И., Барбараш О.Л.</copyright-holder><copyright-holder xml:lang="en">Pecherina T.B., Sinkova M.N., Guselnikova Y.I., Barbarash O.L.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/1812">https://www.nii-kpssz.com/jour/article/view/1812</self-uri><abstract><sec><title>Основные положения</title><p>Основные положения</p><p>Понимание особенностей взаимодействия различных заболеваний у пациентов с острой сердечной недостаточностью и острой декомпенсацией хронической сердечной недостаточности имеет ключевое значение для разработки эффективных стратегий профилактики и лечения, направленных на улучшение качества медицинской помощи и снижение заболеваемости и смертности в этой группе пациентов.</p></sec><sec><title> </title><p> </p></sec><sec><title>Резюме</title><p>Резюме</p><p>Острая сердечная недостаточность (ОСН) и острая декомпенсация хронической сердечной недостаточности (ОДСН) являются неотложными клиническими состояниями, которые часто сопровождаются мультиморбидностью – одновременным наличием нескольких хронических заболеваний, что значительно усложняет диагностику, лечение и прогнозирование исходов у данных пациентов. В обзоре рассмотрены наиболее распространенные коморбидные состояния, такие как артериальная гипертензия, сахарный диабет, хроническая болезнь почек, ожирение, дефицит железа и хроническое обструктивное заболевание легких. Каждый из этих факторов как по отдельности, так и в совокупности влияет на течение ОСН и ОДСН, увеличивая риск осложнений и ухудшая качество жизни пациентов. Подчеркнута важность комплексного подхода в ведении больных ОСН/ОДСН, осложненных мультиморбидностью. Раннее выявление и патогенетическая терапия сопутствующих заболеваний позволяют снизить частоту госпитализаций, улучшить функциональные возможности и повысить продолжительность жизни пациентов. Понимание особенностей взаимодействия различных заболеваний у пациентов с ОСН/ОДСН имеет ключевое значение для разработки эффективных стратегий профилактики и лечения, направленных на улучшение качества медицинской помощи и снижение заболеваемости и смертности в данной группе больных.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Highlights</title><p>Highlights </p><p>Understanding the interaction between various diseases in patients with acute heart failure and acute decompensated heart failure is key to developing effective prevention and management strategies aimed at improving the quality of medical care and reducing morbidity and mortality among this group of patients.</p></sec><sec><title> </title><p> </p></sec><sec><title>Abstract</title><p>Abstract</p><p>Acute decompensated heart failure (ADHF) is a serious clinical condition that is often accompanied by multimorbidity, i.e. the presence of several chronic diseases simultaneously. These comorbidities significantly complicate the diagnosis, treatment and prognosis of outcomes in patients with ADHF. The review considers the most common comorbid conditions, such as arterial hypertension, diabetes mellitus, chronic kidney disease, obesity, depression and cognitive impairment. Each of these factors individually, as well as together (synergistically), affects the course of ADHF, increasing the risk of complications and worsening the patient's quality of life. Emphasizes the importance of an integrated approach to the management of patients with ADHF and multimorbidity. Early detection and pathogenetic therapy of comorbidities can reduce the frequency of hospitalizations, improve the functional capabilities of patients and increase life expectancy. Thus, understanding the interactions between various diseases in patients with ADHF is key to developing effective prevention and treatment strategies aimed at improving the quality of medical care and reducing morbidity and mortality in this group of patients.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Сердечная недостаточность</kwd><kwd>Мультиморбидность</kwd><kwd>Факторы риска</kwd><kwd>Прогноз</kwd><kwd>Острая декомпенсация сердечной недостаточности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Heart failure</kwd><kwd>Multimorbidity</kwd><kwd>Risk factors</kwd><kwd>Prognosis</kwd><kwd>Acute decompensation of heart failure</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Исследование выполнено в рамках фундаментальной темы № 0419-2022-0002 «Разработка инновационных моделей управления риском развития болезней системы кровообращения с учетом коморбидности на основе изучения фундаментальных, клинических, эпидемиологических механизмов и организационных технологий медицинской помощи в условиях промышленного региона Сибири», утвержденной решением Ученого совета НИИ КПССЗ № 15 от 24.12.2021(научный руководитель – академик РАН О.Л. 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