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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2017-1-</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-200</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE STUDY</subject></subj-group></article-categories><title-group><article-title>ЛУЧЕВОЕ ПОРАЖЕНИЕ КЛАПАННОГО АППАРАТА СЕРДЦА</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жданова</surname><given-names>Ирина Всеволодовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней, ассистент</p></bio><email xlink:type="simple">zhdir@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Елена Викторовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней, доцент</p></bio><email xlink:type="simple">aliska@k66.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Александр Викторович</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д.м.н., профессор, заведующий отделением</p></bio><email xlink:type="simple">office@okb1.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иофин</surname><given-names>Александр Ильич</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующий отделением</p></bio><email xlink:type="simple">iofin@okb1.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быков</surname><given-names>Александр Николаевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-кардиолог</p></bio><email xlink:type="simple">Sashacor83@Yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зиятдинов</surname><given-names>Данил Жамилевич</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">office@okb1.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО УГМУ Минздрава России<country>Россия</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ СО «СОКБ № 1», кардиохирургическое отделение № 1</aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ГБУЗ СО «СОКБ № 1», отделение плановой кардиологии</aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>29</day><month>08</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><elocation-id>200</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Жданова И.В., Кузнецова Е.В., Михайлов А.В., Иофин А.И., Быков А.Н., Зиятдинов Д.Ж., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Жданова И.В., Кузнецова Е.В., Михайлов А.В., Иофин А.И., Быков А.Н., Зиятдинов Д.Ж.</copyright-holder><copyright-holder xml:lang="en">Жданова И.В., Кузнецова Е.В., Михайлов А.В., Иофин А.И., Быков А.Н., Зиятдинов Д.Ж.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/200">https://www.nii-kpssz.com/jour/article/view/200</self-uri><abstract><p>Увеличение продолжительности жизни пациентов после комплексной терапии рака молочной железы сопровождается ростом отдаленной постлучевой патологии сердца. Несвоевременная диагностика и коррекция этих осложнений приводит к ухудшению качества жизни пациентов и увеличивает риск сердечной смертности. Представлен клинический случай развития порока аортального клапана в отдаленном периоде после применения лучевой терапии у пациентки с левосторонней локализацией рака молочной железы.</p></abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>лучевая терапия</kwd><kwd>аортальный стеноз</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Clarke M., Collins R., Darby S. et al. Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials. Lancet 2005; 366: 2087-2106.</mixed-citation><mixed-citation xml:lang="en">Clarke M., Collins R., Darby S. et al. 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