References

kpccz

Комплексные проблемы сердечно-сосудистых заболеваний

Complex Issues of Cardiovascular Diseases

2306-12782587-9537

Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”

10.17802/2306-1278-2016-3-99-107

kpccz-214

Research Article

АНАЛИТИЧЕСКИЕ ОБЗОРЫ

ANALYTICAL REVIEWS

ДОСТИЖЕНИЯ И ПЕРСПЕКТИВЫ В ОБЛАСТИ РАЗРАБОТКИ ГЕН-ВЫДЕЛЯЮЩИХ КОРОНАРНЫХ СТЕНТОВ

ACHIEVEMENTS AND PROSPECTS IN THE FIELD OF GENE-ELUTING CORONARY STENTS

Фаттахов

Н. С.

Fattakhov

N. S.

Куликов

Д. И.

Kulikov

D. I.

Литвинова

Л. С.

Litvinova

L. S.

Для корреспонденции: Литвинова Лариса Сергеевна Адрес: 236016, Калининград, ул. Боткина, 3 Тел.: 8 (4012) 59-55-95 – доб. 6631 E-mail: larisalitvinova@yandex.ru

For correspondence: Litvinova Larisa Address: 3, Botkina st.,Kaliningrad, 236016, Russian Federation Tel.: +7 (4012) 59-55-95 – ext. 6631 E-mail: larisalitvinova@yandex.ru

larisalitvinova@yandex.ru

Балтийский федеральный университет имени Иммануила Канта, КалининградРоссияImmanuel Kant Baltic Federal University, KaliningradRussian Federation

Северо-Западный государственный медицинский университет им. И. И. Мечникова, Санкт-ПетербургРоссияNorth-Western State Medical University named after I. I. Mechnikov, Saint-PetersburgRussian Federation

2016

31082016

0399107

2016

Фаттахов Н.С., Куликов Д.И., Литвинова Л.С.

Fattakhov N.S., Kulikov D.I., Litvinova L.S.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.nii-kpssz.com/jour/article/view/214

В настоящем обзоре систематизированы основные современные разработки и достижения в области ген-выделяющих стентов; обсуждены их преимущества и недостатки как потенциальной альтернативы непокрытым металлическим стентам и стентам, выделяющим лекарства. Рассмотрены основные стратегии оптимизации, необходимые для перевода основанных на применении ген-выделяющих стентов технологий из экспериментальной сферы в клиническую медицину.

In this paper, we summarize the main recent developments and achievements in the field of gene-eluting stents, their advantages and disadvantages as a potential alternative to the bare metal stents and drug-eluting stents are discussed. The basic optimization strategies required for the translation of technologies based on the use of gene-eluting stents from experimental sphere to clinical medicine are examined.

ген-выделяющий стентгенрестенозвекторишемическая болезнь сердцачрескожное коронарное вмешательство

gene-eluting stentrestenosisvectorcoronary heart diseasepercutaneous coronary intervention

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The authors declare that there are no conflicts of interest present.