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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2014-1-36-41</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-22</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ НАЛИЧИЯ МУЛЬТИФОКАЛЬНОГО АТЕРОСКЛЕРОЗА НА КАЧЕСТВО ЖИЗНИ БОЛЬНЫХ C ИБС</article-title><trans-title-group xml:lang="en"><trans-title>EFFECT OF POLYVASCULAR DISEASE ON QUALITY OF LIFE OF CORONARY ARTERY DISEASE PATIENTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сумин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sumin</surname><given-names>A. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Моськин</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskin</surname><given-names>M. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Безденежных</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bezdenezhnyh</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лаборатории патологии кровообращения</p><p>Адрес для переписки:650002, г. Кемерово, Сосновый бульвар, д. 6. Тел. +7(3842) 64-44-61</p></bio><bio xml:lang="en"><p>senior research associate of blood circulation pathology laboratory</p><p>Correspondence address:6, Sosnoviy blvd., Kemerovo, 650002. Tel. +7 (3842) 64-44-61</p></bio><email xlink:type="simple">bezdav@cardio.kem.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корок</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korok</surname><given-names>E. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щеглова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Scheglova</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» Сибирского отделения Российской академии медицинских наук, Кемерово<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution Research Institute for Complex Problems of Cardiovascular Diseases, Siberian Department of Russian Academy of Medical Sciences, Kemerovo<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2015</year></pub-date><volume>0</volume><issue>1</issue><fpage>36</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сумин А.Н., Моськин М.Г., Безденежных А.В., Корок Е.В., Щеглова А.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Сумин А.Н., Моськин М.Г., Безденежных А.В., Корок Е.В., Щеглова А.В.</copyright-holder><copyright-holder xml:lang="en">Sumin A.N., Moskin M.G., Bezdenezhnyh A.V., Korok E.V., Scheglova A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/22">https://www.nii-kpssz.com/jour/article/view/22</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучение влияния наличия мультифокального атеросклероза (МФА) на качество жизни (КЖ) у больных с ИБС.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследовано 807 больных с ИБС (возраст 59,0 ± 8,0 года; 648 мужчин и 159 женщин), обследовавшихся перед плановой операцией коронарного шунтирования (КШ). Пациенты дополнительно были обследованы на предмет выявления у них субклинических стенозов некоронарных артерий для выявления признаков МФА (учитывали стенозы артерий 30 % и более). Сформированы следующие группы: группа с МФА (n = 336) и группа без МФА (n = 473). Группы были сопоставлены по уровню качества жизни и депрессии. КЖ анализировали с помощью опросника SF-36, уровень депрессии – с помощью опросника «Шкала депрессии».</p></sec><sec><title>Результаты</title><p>Результаты. В группе МФА интегральные показатели КЖ были ниже по сравнению с группой без МФА как по физическому (69 (51,5; 72,3) и 71,3 (61,3; 75,8) балла; р = 0,004), так и психологическому компоненту (62,8 (48,5; 72,0) и 63,5 (57,0; 72,8) балла; р = 0,045) КЖ. При множественном регрессионном анализе независимое влияние на физический компонент КЖ оказывали МФА (ОШ = 0,679; 95 %ДИ 0,477–0,966; р = 0,031) и функциональный класс ХСН (ОШ = 0,514; 95 %ДИ 0,378–0,698; р &lt; 0,001), на психологический компонент – функциональный класс ХСН (ОШ = 0,577; 95 %ДИ 0,425–0,784; р &lt; 0,001).</p></sec><sec><title>Заключение</title><p>Заключение. У больных с ИБС с наличием МФА по сравнению с пациентами с изолированным поражением коронарных артерий отмечаются более высокий уровень депрессии и снижение качества жизни как по отдельным шкалам опросника SF-36, так и интегральным показателям физического и психологического компонента КЖ. При многофакторном анализе независимыми факторами, связанными со снижением общего физического здоровья, были наличие МФА и выраженность ХСН, со снижением общего психологического здоровья – только выраженность ХСН.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose. To study the effect of polyvascular disease (PolyVD) on quality of life (QoL) of coronary artery disease (CAD) patients.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We examined 807 CAD patients (59,0 ± 8,0 years old; 648 men and 159 women), who were examined before planned coronary artery bypass surgery (CABG). The patients were additionally examined for subclinical stenosis of non-coronary arteries to identify the signs of PolyVD (artery stenosis 30% and more were included). The following groups were formed: PolyVD group (n = 336) and non-PolyVD group (n = 473). The groups were compared in terms of quality of life and depression. QoL was analyzed with the help of SF36 questionnaire, depression level – with the help of “Depression scale” questionnaire.</p></sec><sec><title>Results</title><p>Results. In PolyVD group integral indicators of QoL were lower compared to non-PolyVD group both as for physical component (69 (51,5;72,3) and 71,3 (61,3;75,8) points; р = 0,004), and for psychological component (62.8 (48.5, 72.0) and 63.5 (57.0, 72.8) points, p = 0.045) of QoL. In multiple regression analysis the independent effect on physical component of QoL was provided by PolyVD (OR = 0,679; 95%CI 0,477–0,966; р = 0,031) and functional class of CHF (OR = 0,514; 95%CI 0,378–0,698; р &lt; 0,001), on psychological component – functional class of CHF (OR = 0,577; 95%CI 0,425–0,784; р&lt;0,001).</p></sec><sec><title>Conclusion</title><p>Conclusion. CAD patients with PolyVD as compared to patients with discrete lesion of coronary arteries have a higher level of depression and reduce of quality of life both as for certain scales of SF-36 questionnaire and integral indicators of physical and psychological components of QoL. In multivariate analysis the independent factors associated with a reduction in overall physical health were PolyVD presence and CHF severity, associated with a reduction in overall psychological health – only CHF severity.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>мультифокальный атеросклероз</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>polyvascular disease</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Возможность использования модифицированной шкалы EUROSCORE для оценки годового прогноза коронарного шунтирования у пациентов с мультифокальным атеросклерозом / Л. С. Барбараш [и др.] // Патология кровообращения и кардиохирургия. 2010. № 2. 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