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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2016-4-81-86</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-240</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНВАЗИВНАЯ КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INVASIVE CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>ФРАКЦИОННЫЙ РЕЗЕРВ КАК СПОСОБ ОПРЕДЕЛЕНИЯ ЗНАЧИМОСТИ ТАНДЕМНЫХ И БИФУРКАЦИОННЫХ СТЕНОЗОВ, ПОРАЖЕНИЯ СТВОЛА ЛЕВОЙ КОРОНАРНОЙ АРТЕРИИ J. MALLIDI, MD, MHS; A. LOTFI, MD, FSCAI (Перевод выполнили Н. А. Кочергин , А. М. Кочергина)</article-title><trans-title-group xml:lang="en"><trans-title>FRACTIONAL FLOW RESERVE FOR THE EVALUATION Of TANDEM AND BIFURCATION LESIONS, LEFT MAIN, AND ACUTE CORONARY SYNDROMES J. MALLIDI, MD, MHS; A. LOTFI, MD, FSCAI (Authors of translation N. А. Kochergin , A. M. Kochergina)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КОЧЕРГИН</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>KOCHERGIN</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адрес: 650002, Кемерово,Сосновый бульвар, 6 Тел.: +7-908-952-32-35</p></bio><bio xml:lang="en"><p>Address: 6, Sosnoviy blvd., Kemerovo, 650002, Russian Federation Tel.: +7-908-952-32-35</p></bio><email xlink:type="simple">nikotwin@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КОЧЕРГИНА</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>KOCHERGINA</surname><given-names>A. M.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>81</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; КОЧЕРГИН Н.А., КОЧЕРГИНА А.М., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">КОЧЕРГИН Н.А., КОЧЕРГИНА А.М.</copyright-holder><copyright-holder xml:lang="en">KOCHERGIN N.A., KOCHERGINA A.M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/240">https://www.nii-kpssz.com/jour/article/view/240</self-uri><abstract><p>Пациенты с тандемными и бифуркационными стенозами, поражением ствола левой коронарной артерии и острым коронарным синдромом не включаются в клинические исследования, изучающие фракционный резерв кровотока. Измерение фракционного резерва кровотока, а также интерпретация его результатов представляют особые затруднения, так как в каждом случае имеются особенности коронарной гемодинамики. Согласно имеющимся данным, определение фракционного резерва кровотока при проведении реваскуляризации миокарда является безопасным и эффективным методом, однако доказательная база недостаточна, что обусловливает потребность в дальнейших исследованиях.</p></abstract><trans-abstract xml:lang="en"><p>Subjects with tandem lesions bifurcation lesions, left main disease and acute coronary syndrome are not included in trials supporting fractional flow reserve (FFR)-guided revascularization. Assessment and interpretation of FFR in these clinical scenarios is technically challenging due to the unique changes in flow hemodynamics in each of these situations. The existing literature supports the safety of using FFR to guide revascularization in these situations; however, the evidence is limited and further research is warranted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фракционный резерв кровотока</kwd><kwd>тандемный стеноз</kwd><kwd>бифуркационные поражения</kwd><kwd>поражение ствола левой коронарной артерии.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>FFR</kwd><kwd>tandem lesions</kwd><kwd>bifurcation lesions</kwd><kwd>left main disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pijls N. H., van Son J. A., Kirkeeide R. L., De Bruyne B., Gould K. L. Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty. Circulation 1993; 87 (4): 1354–1367.</mixed-citation><mixed-citation xml:lang="en">Pijls N. H., van Son J. A., Kirkeeide R. L., De Bruyne B., Gould K. L. Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty. Circulation 1993; 87 (4): 1354–1367.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Pijls N. H., van Schaardenburgh P., Manoharan G., Boersma E., Bech J.-W., van’t Veer M. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow- up of the DEFER Study. J. Am. Coll. Cardiol. 2007; 49 (21): 2105–2111. DOI:10.1016/j.jacc.2007.01.087.</mixed-citation><mixed-citation xml:lang="en">Pijls N. H., van Schaardenburgh P., Manoharan G., Boersma E., Bech J.-W., van’t Veer M. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow- up of the DEFER Study. J. Am. Coll. Cardiol. 2007; 49 (21): 2105–2111. DOI:10.1016/j.jacc.2007.01.087.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Tonino P. A., De Bruyne B., Pijls N. H., Siebert U., Ikeno F., van’t Veer M. S. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N. Engl. J. Med. 2009; 360 (3): 213–224. DOI: 10.1056/NEJMoa0807611.</mixed-citation><mixed-citation xml:lang="en">Tonino P. A., De Bruyne B., Pijls N. H., Siebert U., Ikeno F., van’t Veer M. S. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N. Engl. J. Med. 2009; 360 (3): 213–224. DOI: 10.1056/NEJMoa0807611.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">De Bruyne B., Fearon W. F., Pijls N. H., Barbato E., Tonino P., Piroth Z. Fractional flow reserve-guided PCI for stable coronary artery disease. N. Engl. J. Med. 2014; 37 (13): 1208–1217. DOI: 10.1056/NEJMoa1408758.</mixed-citation><mixed-citation xml:lang="en">De Bruyne B., Fearon W. F., Pijls N. H., Barbato E., Tonino P., Piroth Z. Fractional flow reserve-guided PCI for stable coronary artery disease. N. Engl. J. Med. 2014; 37 (13): 1208–1217. DOI: 10.1056/NEJMoa1408758.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">De Bruyne B., Pijls N. H., Heyndrickx G. R., Hodeige D., Kirkeeide R., Gould K. L. Pressure- derived fractional flow reserve to assess serial epicardial stenoses: theoretical basis and animal validation. Circulation. 2000; 101 (15): 1840–1847.</mixed-citation><mixed-citation xml:lang="en">De Bruyne B., Pijls N. H., Heyndrickx G. R., Hodeige D., Kirkeeide R., Gould K. L. Pressure- derived fractional flow reserve to assess serial epicardial stenoses: theoretical basis and animal validation. Circulation. 2000; 101 (15): 1840–1847.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Pijls N. H., De Bruyne B., Bech G. J., Liistro F., Heyndrickx G. R., Bonnier H. J. Coronary pressure measurement to assess the hemodynamic significance of serial stenoses within one coronary artery: validation in humans. Circulation. 2000; 102 (19): 2371–2377. DOI: http://dx.doi.org/10.1161/01.CIR.102.19.2371.</mixed-citation><mixed-citation xml:lang="en">Pijls N. H., De Bruyne B., Bech G. J., Liistro F., Heyndrickx G. R., Bonnier H. J. Coronary pressure measurement to assess the hemodynamic significance of serial stenoses within one coronary artery: validation in humans. Circulation. 2000; 102 (19): 2371–2377. DOI: http://dx.doi.org/10.1161/01.CIR.102.19.2371.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gould K. L., Nakagawa Y., Nakagawa K., Sdringola S., Hess M. J., Haynie M. Frequency and clinical implications of fluid dynamically significant diffuse coronary artery disease manifest as graded, longitudinal, base-to-apex myocardial perfusion abnormalities by noninvasive positron emission tomography. Circulation. 2000; 101 (16): 1931–1939.</mixed-citation><mixed-citation xml:lang="en">Gould K. L., Nakagawa Y., Nakagawa K., Sdringola S., Hess M. J., Haynie M. Frequency and clinical implications of fluid dynamically significant diffuse coronary artery disease manifest as graded, longitudinal, base-to-apex myocardial perfusion abnormalities by noninvasive positron emission tomography. Circulation. 2000; 101 (16): 1931–1939.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Seiler C., Kirkeeide R. L., Gould K. L. Basic structurefunction relations of the epicardial coronary vascular tree. Basis of quantitative coronary arteriography for diffuse coronary artery disease. Circulation. 1992; 85 (6): 1987–2003.</mixed-citation><mixed-citation xml:lang="en">Seiler C., Kirkeeide R. L., Gould K. L. Basic structurefunction relations of the epicardial coronary vascular tree. Basis of quantitative coronary arteriography for diffuse coronary artery disease. Circulation. 1992; 85 (6): 1987–2003.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kim H. L., Koo B. K., Nam C. W., Doh J. H., Kim J. H., Yang H. M. et al. Clinical and physiological outcomes of fractional flow reserve-guided percutaneous coronary intervention in patients with serial stenoses within one coronary artery. JACC. Cardiovasc. Interv. 2012; 5 (10): 1013–1018. DOI: 10.1016/j.jcin.2012.06.017.</mixed-citation><mixed-citation xml:lang="en">Kim H. L., Koo B. K., Nam C. W., Doh J. H., Kim J. H., Yang H. M. et al. Clinical and physiological outcomes of fractional flow reserve-guided percutaneous coronary intervention in patients with serial stenoses within one coronary artery. JACC. Cardiovasc. Interv. 2012; 5 (10): 1013–1018. DOI: 10.1016/j.jcin.2012.06.017.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Park S. J., Ahn J. M., Pijls N. H., Bruyne B., Shim E. B., Kim Y. T. et al. Validation of functional state of coronary tandem lesions using computational flow dynamics. Am. J. Cardiol. 2012; 110 (11): 1578–1584. DOI: 10.1016/j.amjcard. 2012.07.023.</mixed-citation><mixed-citation xml:lang="en">Park S. J., Ahn J. M., Pijls N. H., Bruyne B., Shim E. B., Kim Y. T. et al. Validation of functional state of coronary tandem lesions using computational flow dynamics. Am. J. Cardiol. 2012; 110 (11): 1578–1584. DOI: 10.1016/j.amjcard. 2012.07.023.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Louvard Y., Thomas M., Dzavik V., Hildick-Smith D., Galassi A. R., Pan M. et al. Classification of coronary artery bifurcation lesions and treatments: time for a consensus! Catheter. Cardiovasc. Interv. 2008; 71 (2): 175–183. DOI: 10.1002/ccd.21314.</mixed-citation><mixed-citation xml:lang="en">Louvard Y., Thomas M., Dzavik V., Hildick-Smith D., Galassi A. R., Pan M. et al. Classification of coronary artery bifurcation lesions and treatments: time for a consensus! Catheter. Cardiovasc. Interv. 2008; 71 (2): 175–183. DOI: 10.1002/ccd.21314.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Koo B. K., De Bruyne B. FFR in bifurcation stenting: what have we learned? EuroIntervention. 2010; 6 (Suppl J): 94–98.</mixed-citation><mixed-citation xml:lang="en">Koo B. K., De Bruyne B. FFR in bifurcation stenting: what have we learned? EuroIntervention. 2010; 6 (Suppl J): 94–98.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ziaee A., Parham W. A., Herrmann S. C., Stewart R. E., Lim M. J., Kern M. J. Lack of relation between imaging and physiology in ostial coronary artery narrowings. Am. J. Cardiol. 2004; 93 (11): 1404–1407. DOI: 10.1016/j.amjcard.2004.02.041.</mixed-citation><mixed-citation xml:lang="en">Ziaee A., Parham W. A., Herrmann S. C., Stewart R. E., Lim M. J., Kern M. J. Lack of relation between imaging and physiology in ostial coronary artery narrowings. Am. J. Cardiol. 2004; 93 (11): 1404–1407. DOI: 10.1016/j.amjcard.2004.02.041.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Koo B. K., Waseda K., Kang H. J., Kim H. S., Nam C. W., Hur S. H. et al. Anatomic and functional evaluation of bifurcation lesions undergoing percutaneous coronary intervention. Circ. Cardiovasc. Interv. 2010; 3 (2): 113–119. DOI: 10.1161/CIRCINTERVENTIONS.109.887406.</mixed-citation><mixed-citation xml:lang="en">Koo B. K., Waseda K., Kang H. J., Kim H. S., Nam C. W., Hur S. H. et al. Anatomic and functional evaluation of bifurcation lesions undergoing percutaneous coronary intervention. Circ. Cardiovasc. Interv. 2010; 3 (2): 113–119. DOI: 10.1161/CIRCINTERVENTIONS.109.887406.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Hildick-Smith D., de Belder A. J., Cooter N., Сurzen N. P., Clayton T. C., Oldroyd K. G. et al. Randomized trial of simple versus complex drugeluting stenting for bifurcation lesions: the British Bifurcation Coronary Study: old, new, and evolving strategies. Circulation. 2010; 121 (10): 1235–1243. DOI: 10.1161/CIRCULATIONAHA.109.888297.</mixed-citation><mixed-citation xml:lang="en">Hildick-Smith D., de Belder A. J., Cooter N., Сurzen N. P., Clayton T. C., Oldroyd K. G. et al. Randomized trial of simple versus complex drugeluting stenting for bifurcation lesions: the British Bifurcation Coronary Study: old, new, and evolving strategies. Circulation. 2010; 121 (10): 1235–1243. DOI: 10.1161/CIRCULATIONAHA.109.888297.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Niemela M., Kervinen K., Erglis A., Holm N. R., Maeng M., Christiansen E. H. et al. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic-Baltic Bifurcation Study III. Circulation. 2011; 123 (1): 79–86. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.110.966879.</mixed-citation><mixed-citation xml:lang="en">Niemela M., Kervinen K., Erglis A., Holm N. R., Maeng M., Christiansen E. H. et al. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic-Baltic Bifurcation Study III. Circulation. 2011; 123 (1): 79–86. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.110.966879.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Colombo A., Bramucci E., Sacca S., Violini R., Lettieri C., Zanini R. et al. Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus- Eluting Stents) Study. Circulation. 2009; 119 (1): 71–78. DOI: 10.1161/CIRCULATIONAHA.108.808402.</mixed-citation><mixed-citation xml:lang="en">Colombo A., Bramucci E., Sacca S., Violini R., Lettieri C., Zanini R. et al. Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus- Eluting Stents) Study. Circulation. 2009; 119 (1): 71–78. DOI: 10.1161/CIRCULATIONAHA.108.808402.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Williams A. R., Koo B. K., Gundert T. J., Fitzgerald P. J., LaDisa J. F. Jr. Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. J. Appl. Physiol. (1985). 2010; 109 (2): 532–540. DOI: 10.1152/japplphysiol.00086.2010.</mixed-citation><mixed-citation xml:lang="en">Williams A. R., Koo B. K., Gundert T. J., Fitzgerald P. J., LaDisa J. F. Jr. Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. J. Appl. Physiol. (1985). 2010; 109 (2): 532–540. DOI: 10.1152/japplphysiol.00086.2010.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Gao X. F., Zhang Y. J., Tian N. L., Wu W., Li M. H., Bourantas C. V. et al. Stenting strategy for coronary artery bifurcation with drug-eluting stents: a meta-analysis of nine randomised trials and systematic review. EuroIntervention. 2014; 10 (5): 561–569. DOI: 10.4244/EIJY14M06_06.</mixed-citation><mixed-citation xml:lang="en">Gao X. F., Zhang Y. J., Tian N. L., Wu W., Li M. H., Bourantas C. V. et al. Stenting strategy for coronary artery bifurcation with drug-eluting stents: a meta-analysis of nine randomised trials and systematic review. EuroIntervention. 2014; 10 (5): 561–569. DOI: 10.4244/EIJY14M06_06.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Koo B. K., Park K. W., Kang H. J., Cho Y. S., Chung W. Y., Youn T. J. et al. Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve. Eur. Heart. J. 2008; 29 (6): 726–732. DOI: http://dx.doi.org/10.1093/eurheartj/ehn045.</mixed-citation><mixed-citation xml:lang="en">Koo B. K., Park K. W., Kang H. J., Cho Y. S., Chung W. Y., Youn T. J. et al. Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve. Eur. Heart. J. 2008; 29 (6): 726–732. DOI: http://dx.doi.org/10.1093/eurheartj/ehn045.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Lee B. K., Choi H. H., Hong K. S., Kim B. K., Shim J., Kim J. S. et al. Efficacy of fractional flow reserve measurements at side branch vessels treated with the crush stenting technique in true coronary bifurcation lesions. Clin. Cardiol. 2010; 33 (8): 490–494. DOI: 10.1002/clc.20799.</mixed-citation><mixed-citation xml:lang="en">Lee B. K., Choi H. H., Hong K. S., Kim B. K., Shim J., Kim J. S. et al. Efficacy of fractional flow reserve measurements at side branch vessels treated with the crush stenting technique in true coronary bifurcation lesions. Clin. Cardiol. 2010; 33 (8): 490–494. DOI: 10.1002/clc.20799.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Park S. H., Koo B. K. Clinical applications of fractional flow reserve in bifurcation lesions. J. Geriatr. Cardiol. 2012; 9 (3): 278–284.</mixed-citation><mixed-citation xml:lang="en">Park S. H., Koo B. K. Clinical applications of fractional flow reserve in bifurcation lesions. J. Geriatr. Cardiol. 2012; 9 (3): 278–284.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ratcliffe J. A., Huang Y., Kwan T. A novel technique in the use of fractional flow reserve in coronary artery bifurcation lesions. Int. J. Angiol. 2012; 21 (1): 59–62.</mixed-citation><mixed-citation xml:lang="en">Ratcliffe J. A., Huang Y., Kwan T. A novel technique in the use of fractional flow reserve in coronary artery bifurcation lesions. Int. J. Angiol. 2012; 21 (1): 59–62.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Yusuf S., Zucker D., Peduzzi P., Fisher L. D., Takaro T., Kennedy J. W. et al. Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration. Lancet. 1994; 344 (8922): 563–570.</mixed-citation><mixed-citation xml:lang="en">Yusuf S., Zucker D., Peduzzi P., Fisher L. D., Takaro T., Kennedy J. W. et al. Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration. Lancet. 1994; 344 (8922): 563–570.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Puri R., Kapadia S. R., Nicholls S. J., Harvey J. E., Kataoka Y., Tuzcu E. M. Optimizing outcomes during left main percutaneous coronary intervention with intravascular ultrasound and fractional flow reserve: the current state of evidence. JACC Cardiovasc. Interv. 2012; 5 (7): 697–707. DOI: 10.1016/j.jcin.2012.02.018.</mixed-citation><mixed-citation xml:lang="en">Puri R., Kapadia S. R., Nicholls S. J., Harvey J. E., Kataoka Y., Tuzcu E. M. Optimizing outcomes during left main percutaneous coronary intervention with intravascular ultrasound and fractional flow reserve: the current state of evidence. JACC Cardiovasc. Interv. 2012; 5 (7): 697–707. DOI: 10.1016/j.jcin.2012.02.018.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Lindstaedt M., Spiecker M., Perings C., Lawo T., Yazar A., Holland-Letz T. et al. How good are experienced interventional cardiologists at predicting the functional significance of intermediate or equivocal left main coronary artery stenoses? Int. J. Cardiol. 2007; 120 (2): 254–261. DOI: 10.1016/j.ijcard.2006.11.220.</mixed-citation><mixed-citation xml:lang="en">Lindstaedt M., Spiecker M., Perings C., Lawo T., Yazar A., Holland-Letz T. et al. How good are experienced interventional cardiologists at predicting the functional significance of intermediate or equivocal left main coronary artery stenoses? Int. J. Cardiol. 2007; 120 (2): 254–261. DOI: 10.1016/j.ijcard.2006.11.220.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Hamilos M., Muller O., Cuisset T., Ntalianis A., Chlouverakis G., Sarno G. et al. Long-term clinical outcome after fractional flow reserveguided treatment in patients with angiographically equivocal left main coronary artery stenosis. Circulation. 2009; 120 (15): 1505–1512. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.109.850073.</mixed-citation><mixed-citation xml:lang="en">Hamilos M., Muller O., Cuisset T., Ntalianis A., Chlouverakis G., Sarno G. et al. Long-term clinical outcome after fractional flow reserveguided treatment in patients with angiographically equivocal left main coronary artery stenosis. Circulation. 2009; 120 (15): 1505–1512. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.109.850073.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Courtis J., Rodes-Cabau J., Larose E., Potvin J. M., Déry J. P., Larochellière R. D. et al. Usefulness of coronary fractional flow reserve measurements in guiding clinical decisions in intermediate or equivocal left main coronary stenoses. Am. J. Cardiol. 2009; 103 (7): 943– 949. DOI: 10.1016/j.amjcard.2008.11.054.</mixed-citation><mixed-citation xml:lang="en">Courtis J., Rodes-Cabau J., Larose E., Potvin J. M., Déry J. P., Larochellière R. D. et al. Usefulness of coronary fractional flow reserve measurements in guiding clinical decisions in intermediate or equivocal left main coronary stenoses. Am. J. Cardiol. 2009; 103 (7): 943– 949. DOI: 10.1016/j.amjcard.2008.11.054.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Bulkley B. H., Roberts W. C. Atherosclerotic narrowing of the left main coronary artery. A necropsy analysis of 152 patients with fatal coronary heart disease and varying degrees of left main narrowing. Circulation. 1976; 53 (5): 823–828.</mixed-citation><mixed-citation xml:lang="en">Bulkley B. H., Roberts W. C. Atherosclerotic narrowing of the left main coronary artery. A necropsy analysis of 152 patients with fatal coronary heart disease and varying degrees of left main narrowing. Circulation. 1976; 53 (5): 823–828.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Yong A. S., Daniels D., De Bruyne B., Kim H. S., Ikeno F., Lyons J. et al. Fractional flow reserve assessment of left main stenosis in the presence of downstream coronary stenoses. Circ. Cardiovasc. Interv. 2013; 6 (2): 161–165.</mixed-citation><mixed-citation xml:lang="en">Yong A. S., Daniels D., De Bruyne B., Kim H. S., Ikeno F., Lyons J. et al. Fractional flow reserve assessment of left main stenosis in the presence of downstream coronary stenoses. Circ. Cardiovasc. Interv. 2013; 6 (2): 161–165.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Jasti V., Ivan E., Yalamanchili V., Wongpraparut N., Leesar M. A. Correlations between fractional flow reserve and intravascular ultrasound in patients with an ambiguous left main coronary artery stenosis. Circulation. 2004; 110 (18): 2831–2836. DOI: http://dx.doi.org/10.1161/01.CIR.0000146338.62813.E7.</mixed-citation><mixed-citation xml:lang="en">Jasti V., Ivan E., Yalamanchili V., Wongpraparut N., Leesar M. A. Correlations between fractional flow reserve and intravascular ultrasound in patients with an ambiguous left main coronary artery stenosis. Circulation. 2004; 110 (18): 2831–2836. DOI: http://dx.doi.org/10.1161/01.CIR.0000146338.62813.E7.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Jeremias A., Whitbourn R. J., Filardo S. D., Fitzgerald P. J., Cohen D. J., Tuzcu E. M. et al. Adequacy of intracoronary versus intravenous adenosine-induced maximal coronary hyperemia for fractional flow reserve measurements. Am. Heart. J. 2000; 140 (4): 651–657. DOI: 10.1067/mhj.2000.109920.</mixed-citation><mixed-citation xml:lang="en">Jeremias A., Whitbourn R. J., Filardo S. D., Fitzgerald P. J., Cohen D. J., Tuzcu E. M. et al. Adequacy of intracoronary versus intravenous adenosine-induced maximal coronary hyperemia for fractional flow reserve measurements. Am. Heart. J. 2000; 140 (4): 651–657. DOI: 10.1067/mhj.2000.109920.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Lotfi A., Jeremias A., Fearon W. F., Feldman M. D., Mehran R., Messenger J. C. et al. Expert consensus statement on the use of fractional flow reserve, intravascular ultrasound, and optical coherence tomography: a consensus statement of the society of cardiovascular angiography and interventions. Catheter. Cardiovasc. Interv. 2014; 83 (4): 509–518. DOI: 10.1002/ccd.25222.</mixed-citation><mixed-citation xml:lang="en">Lotfi A., Jeremias A., Fearon W. F., Feldman M. D., Mehran R., Messenger J. C. et al. Expert consensus statement on the use of fractional flow reserve, intravascular ultrasound, and optical coherence tomography: a consensus statement of the society of cardiovascular angiography and interventions. Catheter. Cardiovasc. Interv. 2014; 83 (4): 509–518. DOI: 10.1002/ccd.25222.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
