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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2016-4-96-100</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-242</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИТИЧЕСКИЙ ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYTICAL REVIEW</subject></subj-group></article-categories><title-group><article-title>ЛУЧЕВОЕ ПОРАЖЕНИЕ КЛАПАННОГО АППАРАТА СЕРДЦА</article-title><trans-title-group xml:lang="en"><trans-title>RADIATION-ASSOCIATED VALVULAR HEART DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЖДАНОВА</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>ZHDANOVA</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адрес: 620028, Екатеринбург, ул. Репина, 3 Тел.: 8 (343) 351-15-05</p></bio><bio xml:lang="en"><p>Address: 3, Repina st., Ekaterinburg, 620028, Russian Federation Tel.: +7 (343) 351-15-05</p></bio><email xlink:type="simple">zhdir@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КУЗНЕЦОВА</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>KUZNETCOVA</surname><given-names>E. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>МИХАЙЛОВ</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>MIKHAYLOV</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ИОФИН</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>IOFIN</surname><given-names>A. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>БЫКОВ</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>BYKOV</surname><given-names>A. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЗАЯТДИНОВ</surname><given-names>Д. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>ZAIATDINOV</surname><given-names>D. ZH.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение &#13;
высшего образования «Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации, Екатеринбург, Россия<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of Higher Education Ural State Medical University. Ekaterinburg, Russia<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Государственное бюджетное учреждение здравоохранения Свердловской области «Свердловская областная клиническая больница № 1». Екатеринбург, Россия<country>Россия</country></aff><aff xml:lang="en">The Sverdlovsk region Sverdlovsk regional clinical hospital № 1. Ekaterinburg, Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>96</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; ЖДАНОВА И.В., КУЗНЕЦОВА Е.В., МИХАЙЛОВ А.В., ИОФИН А.И., БЫКОВ А.Н., ЗАЯТДИНОВ Д.Ж., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">ЖДАНОВА И.В., КУЗНЕЦОВА Е.В., МИХАЙЛОВ А.В., ИОФИН А.И., БЫКОВ А.Н., ЗАЯТДИНОВ Д.Ж.</copyright-holder><copyright-holder xml:lang="en">ZHDANOVA I.V., KUZNETCOVA E.V., MIKHAYLOV A.V., IOFIN A.I., BYKOV A.N., ZAIATDINOV D.Z.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/242">https://www.nii-kpssz.com/jour/article/view/242</self-uri><abstract><p>Увеличение продолжительности жизни пациентов после комплексной терапии рака молочной железы сопровождается ростом отдаленной постлучевой патологии сердца. Несвоевременная диагностика и коррекция этих осложнений приводит к ухудшению качества жизни пациентов и увеличивает риск сердечной смертности. Представлен клинический случай развития порока аортального клапана в отдаленном периоде после применения лучевой терапии у пациентки с левосторонней локализацией рака молочной железы.</p></abstract><trans-abstract xml:lang="en"><p>The increasing life expectancy of patients after complex therapy for breast cancer is accompanied by the growth of remote postradiation pathology of the heart. Late diagnosis and correction of these complications leads to deterioration in the quality of life of patients and increases the risk of cardiac mortality. Presents a clinical case of development of aortic valve disease in the late period after radiotherapy in the patient with left-sided localization of breast cancer.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>лучевая терапия</kwd><kwd>аортальный стеноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>radiation therapy</kwd><kwd>aortal valvular disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Clarke M., Collins R., Darby S. et al. Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials. Lancet. 2005; 366: 2087–2106.</mixed-citation><mixed-citation xml:lang="en">Clarke M., Collins R., Darby S. et al. 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