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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2017-2-23-31</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-279</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЙ ВЗГЛЯД НА ПРОБЛЕМЫ ЧРЕCКОЖНОГО КОРОНАРНОГО ВМЕШАТЕЛЬСТВА ПРИ ПОРАЖЕНИЯХ СТВОЛА ЛЕВОЙ КОРОНАРНОЙ АРТЕРИИ С ИСПОЛЬЗОВАНИЕМ СТЕНТОВ С ЛЕКАРСТВЕННЫМ ПОКРЫТИЕМ</article-title><trans-title-group xml:lang="en"><trans-title>MODERN VIEW ON THE PROBLEMS OF PERCUTANEOUS CORONARY INTERVENTION IN LESIONS OF LEFT MAIN CORONARY ARTERY USING DRUG-ELUTING STENTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрагимов</surname><given-names>Р. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibragimov</surname><given-names>R. U.</given-names></name></name-alternatives><email xlink:type="simple">maharadja83@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хелимский</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khelimskiy</surname><given-names>D. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крестьянинов</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Krestyaninov</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байструков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Baystrukov</surname><given-names>V. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кретов</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kretov</surname><given-names>E. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Покушалов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pokushalov</surname><given-names>E. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козырь</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozyr</surname><given-names>K. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение «Сибирский федеральный биомедицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “E.N. Meshalkin Siberian Federal Biomedical Research Center”, the Ministry of Healthcare of the Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>07</month><year>2017</year></pub-date><volume>0</volume><issue>2</issue><fpage>23</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ибрагимов Р.У., Хелимский Д.А., Крестьянинов О.В., Байструков В.И., Кретов Е.И., Покушалов Е.А., Козырь К.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Ибрагимов Р.У., Хелимский Д.А., Крестьянинов О.В., Байструков В.И., Кретов Е.И., Покушалов Е.А., Козырь К.В.</copyright-holder><copyright-holder xml:lang="en">Ibragimov R.U., Khelimskiy D.A., Krestyaninov O.V., Baystrukov V.I., Kretov E.I., Pokushalov E.A., Kozyr K.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/279">https://www.nii-kpssz.com/jour/article/view/279</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>стент</kwd><kwd>ствол левой коронарной артерии</kwd><kwd>чрезкожное коронарное вмешательство</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stent</kwd><kwd>the main coronary artery</kwd><kwd>percutaneous coronary intervention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Taylor H.A., Deumite N.J., Chaitman B.R. et al., Asymptomatic left main coronary artery disease in the Coronary Artery Surgery Study (CASS) registry, Circulation 79 (6) (1989) 1171–1179.</mixed-citation><mixed-citation xml:lang="en">Taylor H.A., Deumite N.J., Chaitman B.R. et al., Asymptomatic left main coronary artery disease in the Coronary Artery Surgery Study (CASS) registry, Circulation 79 (6) (1989) 1171–1179.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen V., Gorlin R. Main left coronary artery disease. Clinical experience from 1964–1974. Circulation. 1975; 52: 275–85.</mixed-citation><mixed-citation xml:lang="en">Cohen V., Gorlin R. Main left coronary artery disease. Clinical experience from 1964–1974. Circulation. 1975; 52: 275–85.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Stone P, Goldschlager N. Left main coronary artery disease: review and appraisal. Cardiovasc Med. 1979; 4: 165-177.</mixed-citation><mixed-citation xml:lang="en">Stone P, Goldschlager N. Left main coronary artery disease: review and appraisal. Cardiovasc Med. 1979; 4: 165-177.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Farooq V., Serruys P.W., Stone G.W. et al., Left main coronary artery disease, in Percutaneous Interventional Cardiovascular Medicina, in: The PCR-EAPCI Textbook. PCR Publishing; 2012. pp. 329–405.</mixed-citation><mixed-citation xml:lang="en">Farooq V., Serruys P.W., Stone G.W. et al., Left main coronary artery disease, in Percutaneous Interventional Cardiovascular Medicina, in: The PCR-EAPCI Textbook. PCR Publishing; 2012. pp. 329–405.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Park S.J., Park D.W. Percutaneous coronary intervention with stent implantation versus coronary artery bypass surgery for treatment of left main coronary artery disease: is it time to change guidelines? Circ Cardiovasc Interv. 2009; 2: 59–68.</mixed-citation><mixed-citation xml:lang="en">Park S.J., Park D.W. Percutaneous coronary intervention with stent implantation versus coronary artery bypass surgery for treatment of left main coronary artery disease: is it time to change guidelines? Circ Cardiovasc Interv. 2009; 2: 59–68.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Harskamp R.E., Park D.W. Stenting versus surgery for significant left main disease. Curr Cardiol Rep. 2015; 17: 18.</mixed-citation><mixed-citation xml:lang="en">Harskamp R.E., Park D.W. Stenting versus surgery for significant left main disease. Curr Cardiol Rep. 2015; 17: 18.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Macaya C., Alfonso F., Iniguez A., et al. Stenting for elastic recoil during coronary angioplasty of the left main coronary artery. American Journal of Cardiology. 1992; 70 (1); 105–107</mixed-citation><mixed-citation xml:lang="en">Macaya C., Alfonso F., Iniguez A., et al. Stenting for elastic recoil during coronary angioplasty of the left main coronary artery. American Journal of Cardiology. 1992; 70 (1); 105–107</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Reig J., Petit M. Main trunk of the left coronary artery: anatomic study of the parameters of clinical interest. Clinical Anatomy. 2004; 17 (1): 6–13.</mixed-citation><mixed-citation xml:lang="en">Reig J., Petit M. Main trunk of the left coronary artery: anatomic study of the parameters of clinical interest. Clinical Anatomy. 2004; 17 (1): 6–13.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Maehara A., Mintz G.S., Castagna M.T. et al., Intravascular ultrasound assessment of the stenoses location and morphology in the left main coronary artery in relation to anatomic left main length. American Journal of Cardiology. 2001; 88 (1):1–4.</mixed-citation><mixed-citation xml:lang="en">Maehara A., Mintz G.S., Castagna M.T. et al., Intravascular ultrasound assessment of the stenoses location and morphology in the left main coronary artery in relation to anatomic left main length. American Journal of Cardiology. 2001; 88 (1):1–4.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Oviedo C., Maehara A., Mintz G.S. et al., Intravascular ultrasound classification of plaque distribution in left main coronary artery bifurcations: where is the plaque really located? Circulation: Cardiovascular Interventions. 2010; 3 (2):105–112.</mixed-citation><mixed-citation xml:lang="en">Oviedo C., Maehara A., Mintz G.S. et al., Intravascular ultrasound classification of plaque distribution in left main coronary artery bifurcations: where is the plaque really located? Circulation: Cardiovascular Interventions. 2010; 3 (2):105–112.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">de la Torre Hernandez M., Baz Alonso J.A., Gomez Hospital J.A. et al., Clinical impact of intravascular ultrasound guidance in drug-eluting stent implantation for unprotected left main coronary disease: pooled analysis at the patient-level of 4 registries. JACC: Cardiovascular Interventions. 2014; 7 (3): 244–254</mixed-citation><mixed-citation xml:lang="en">de la Torre Hernandez M., Baz Alonso J.A., Gomez Hospital J.A. et al., Clinical impact of intravascular ultrasound guidance in drug-eluting stent implantation for unprotected left main coronary disease: pooled analysis at the patient-level of 4 registries. JACC: Cardiovascular Interventions. 2014; 7 (3): 244–254</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">O’Keefe J.H. Jr., Hartzler G.O., Rutherford B.D. et al. Left main coronary angioplasty: early and late results of 127 acute and elective procedures. Am J Cardiol. 1989; 64: 144–7.</mixed-citation><mixed-citation xml:lang="en">O’Keefe J.H. Jr., Hartzler G.O., Rutherford B.D. et al. Left main coronary angioplasty: early and late results of 127 acute and elective procedures. Am J Cardiol. 1989; 64: 144–7.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Silvestri M, Barragan P., Sainsous J. et al. Unprotected left main coronary artery stenting: immediate and medium-term outcomes of 140 elective procedures. J Am Coll Cardiol. 2000; 35: 1543–50.</mixed-citation><mixed-citation xml:lang="en">Silvestri M, Barragan P., Sainsous J. et al. Unprotected left main coronary artery stenting: immediate and medium-term outcomes of 140 elective procedures. J Am Coll Cardiol. 2000; 35: 1543–50.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Tan W.A., Tamai H., Park S.J. et al., for the ULTIMA Investigators. Long-term clinical outcomes after unprotected left main trunk percutaneous revascularization in 279 patients. Circulation 2001; 104: 1609–14.</mixed-citation><mixed-citation xml:lang="en">Tan W.A., Tamai H., Park S.J. et al., for the ULTIMA Investigators. Long-term clinical outcomes after unprotected left main trunk percutaneous revascularization in 279 patients. Circulation 2001; 104: 1609–14.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Black A., Cortina R., Bossi I. et al. Unprotected left main coronary artery stenting: correlates of midterm survival and impact of patient selection. J Am Coll Cardiol. 2001; 37: 832–8.</mixed-citation><mixed-citation xml:lang="en">Black A., Cortina R., Bossi I. et al. Unprotected left main coronary artery stenting: correlates of midterm survival and impact of patient selection. J Am Coll Cardiol. 2001; 37: 832–8.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Takagi T., Stankovic G., Finci L. et al. Results and long-term predictors of adverse clinical events after elective percutaneous interventions on unprotected left main coronary artery. Circulation. 2002; 106: 698–702.</mixed-citation><mixed-citation xml:lang="en">Takagi T., Stankovic G., Finci L. et al. Results and long-term predictors of adverse clinical events after elective percutaneous interventions on unprotected left main coronary artery. Circulation. 2002; 106: 698–702.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Park S.J., Hong M.K., Lee C.W. et al. Elective stenting of unprotected left main coronary artery stenosis: effect of debulking before stenting and intravascular ultrasound guidance. J Am Coll Cardiol. 2001; 38: 1054–60.</mixed-citation><mixed-citation xml:lang="en">Park S.J., Hong M.K., Lee C.W. et al. Elective stenting of unprotected left main coronary artery stenosis: effect of debulking before stenting and intravascular ultrasound guidance. J Am Coll Cardiol. 2001; 38: 1054–60.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Осиев А. Г., Мироненко С. П., Кретов Е. И., Бирюков А. В., Ёлкина Д. С., Коледа Н. В., Крестьянинов О. В. Cравнительная клинико-ангиографическая оценка отдаленных результатов коронарного стентирования у больных ишемической болезнью сердца при использовании стентов с различным лекарственным покрытием. Патология кровообращения и кардиохирургия. 2012; 16(2): 45-51. Osiev A. G., Mironenko S. P., Kretov E. I., Biryukov A. V., Elkina D. S., Koleda N. V., Krest'yaninov O. V. Cravnitel'naya kliniko-angiograficheskaya otsenka otdalennykh rezul'tatov koronarnogo stentirovaniya u bol'nykh ishemicheskoy bolezn'yu serdtsa pri ispol'zovanii stentov s razlichnym lekarstvennym pokrytiem. Patologiya krovoobrashcheniya i kardiokhirurgiya. 2012; 16(2): 45-51.</mixed-citation><mixed-citation xml:lang="en">Осиев А. Г., Мироненко С. П., Кретов Е. И., Бирюков А. В., Ёлкина Д. С., Коледа Н. В., Крестьянинов О. В. Cравнительная клинико-ангиографическая оценка отдаленных результатов коронарного стентирования у больных ишемической болезнью сердца при использовании стентов с различным лекарственным покрытием. Патология кровообращения и кардиохирургия. 2012; 16(2): 45-51. Osiev A. G., Mironenko S. P., Kretov E. I., Biryukov A. V., Elkina D. S., Koleda N. V., Krest'yaninov O. V. Cravnitel'naya kliniko-angiograficheskaya otsenka otdalennykh rezul'tatov koronarnogo stentirovaniya u bol'nykh ishemicheskoy bolezn'yu serdtsa pri ispol'zovanii stentov s razlichnym lekarstvennym pokrytiem. Patologiya krovoobrashcheniya i kardiokhirurgiya. 2012; 16(2): 45-51.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Valgimigli M., van Mieghem C.A., Ong A.T. et al. Short- and long-term clinical outcome after drugeluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital registries (RESEARCH and T-SEARCH). Circulation. 2005; 111: 1383–9.</mixed-citation><mixed-citation xml:lang="en">Valgimigli M., van Mieghem C.A., Ong A.T. et al. Short- and long-term clinical outcome after drugeluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital registries (RESEARCH and T-SEARCH). Circulation. 2005; 111: 1383–9.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Chieffo A., Stankovic G., Bonizzoni E. et al. Early and mid-term results of drug-eluting stent implantation in unprotected left main. Circulation. 2005; 111: 791–5.</mixed-citation><mixed-citation xml:lang="en">Chieffo A., Stankovic G., Bonizzoni E. et al. Early and mid-term results of drug-eluting stent implantation in unprotected left main. Circulation. 2005; 111: 791–5.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Erglis A., Narbute I., Kumsars I. et al. A randomized comparison of paclitaxel-eluting stents versus bare-metal stents for treatment of unprotected left main coronary artery stenosis. J Am Coll Cardiol. 2007; 50: 491–7.</mixed-citation><mixed-citation xml:lang="en">Erglis A., Narbute I., Kumsars I. et al. A randomized comparison of paclitaxel-eluting stents versus bare-metal stents for treatment of unprotected left main coronary artery stenosis. J Am Coll Cardiol. 2007; 50: 491–7.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Huang H.W., Brent B.N., Shaw R.E. Trends in percutaneous versus surgical revascularization of unprotected left main coronary stenosis in the drug-eluting stent era: a report from the American College of Cardiology–National Cardiovascular Data Registry (ACC-NCDR). Catheter Cardiovasc Interv. 2006; 68: 867–72.</mixed-citation><mixed-citation xml:lang="en">Huang H.W., Brent B.N., Shaw R.E. Trends in percutaneous versus surgical revascularization of unprotected left main coronary stenosis in the drug-eluting stent era: a report from the American College of Cardiology–National Cardiovascular Data Registry (ACC-NCDR). Catheter Cardiovasc Interv. 2006; 68: 867–72.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Bangalore S., Kumar S., Fusaro M. et al. Shortand long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials. Circulation. 2012; 125: 2873–91.</mixed-citation><mixed-citation xml:lang="en">Bangalore S., Kumar S., Fusaro M. et al. Shortand long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials. Circulation. 2012; 125: 2873–91.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Palmerini T., Biondi-Zoccai G., Della Riva D. et al. Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis. Lancet. 2012; 379: 1393–402.</mixed-citation><mixed-citation xml:lang="en">Palmerini T., Biondi-Zoccai G., Della Riva D. et al. Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis. Lancet. 2012; 379: 1393–402.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Levine G.N., Bates E.R., Blankenship J.C. et al. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation. 2011; 124: e574-e651.</mixed-citation><mixed-citation xml:lang="en">Levine G.N., Bates E.R., Blankenship J.C. et al. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation. 2011; 124: e574-e651.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">King S.B., Smith S.C., Hirshfeld J.W. et al. 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation. 2008; 117: 261-295.</mixed-citation><mixed-citation xml:lang="en">King S.B., Smith S.C., Hirshfeld J.W. et al. 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation. 2008; 117: 261-295.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Windecker S., Kolh P., Alfonso F., Jean-Philippe C., Jochen Crème et al. Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2014; 35: 2541–2619.</mixed-citation><mixed-citation xml:lang="en">Windecker S., Kolh P., Alfonso F., Jean-Philippe C., Jochen Crème et al. Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2014; 35: 2541–2619.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Buszman P.E., Kiesz S.R., Bochenek A. et al., Acute and late outcomes of unprotected left main stenting in comparison with surgical revascularization. Journal of the American College of Cardiology. 2008; 51 (5): 538–545.</mixed-citation><mixed-citation xml:lang="en">Buszman P.E., Kiesz S.R., Bochenek A. et al., Acute and late outcomes of unprotected left main stenting in comparison with surgical revascularization. Journal of the American College of Cardiology. 2008; 51 (5): 538–545.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Serruys P.W., Morice M.C., Kappetein A.P. et al., Percutaneous coronary intervention versus coronary artery bypass grafting for severe coronary artery disease. New England Journal of Medicine. 2009; 360 (10): 961–972.</mixed-citation><mixed-citation xml:lang="en">Serruys P.W., Morice M.C., Kappetein A.P. et al., Percutaneous coronary intervention versus coronary artery bypass grafting for severe coronary artery disease. New England Journal of Medicine. 2009; 360 (10): 961–972.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Mohr F.W., Morice M.C., Kappetein A.P. et al., Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial. Lancet. 2013; 381 (9867): 629–638.</mixed-citation><mixed-citation xml:lang="en">Mohr F.W., Morice M.C., Kappetein A.P. et al., Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial. Lancet. 2013; 381 (9867): 629–638.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Davierwala P., Mohr F.W. Five years after the SYNTAX trial: what have we learnt? European Journal of Cardio- Thoracic Surgery. 2013; 44 (1): 1–3.</mixed-citation><mixed-citation xml:lang="en">Davierwala P., Mohr F.W. Five years after the SYNTAX trial: what have we learnt? European Journal of Cardio- Thoracic Surgery. 2013; 44 (1): 1–3.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Morice M.C., Serruys P.W., Kappetein A.P. et al., Five-year outcomes in patients with left main disease treated with either percutaneous coronary intervention or coronary artery bypass grafting in the synergy between percutaneous coronary intervention with taxus and cardiac surgery trial. Circulation. 2014; 129 (23): 2388–2394.</mixed-citation><mixed-citation xml:lang="en">Morice M.C., Serruys P.W., Kappetein A.P. et al., Five-year outcomes in patients with left main disease treated with either percutaneous coronary intervention or coronary artery bypass grafting in the synergy between percutaneous coronary intervention with taxus and cardiac surgery trial. Circulation. 2014; 129 (23): 2388–2394.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Park S.J., Kim Y.H., Park D.W. et al., Randomized trial of stents versus bypass surgery for left main coronary artery disease. New England Journal of Medicine. 2011; 364 (18): 1718–1727.</mixed-citation><mixed-citation xml:lang="en">Park S.J., Kim Y.H., Park D.W. et al., Randomized trial of stents versus bypass surgery for left main coronary artery disease. New England Journal of Medicine. 2011; 364 (18): 1718–1727.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Ahn M., Roh J.H., Kim Y.H., Park D.W., Yun S.C., Lee P.H. et al., Randomized trial of stents versus bypass surgery for left main coronary artery disease: five-year outcomes of the PRECOMBAT study. Journal of the American College of Cardiology. 2015 May 26; 65(20): 2198-206. doi: 10.1016/j.jacc.2015.03.033</mixed-citation><mixed-citation xml:lang="en">Ahn M., Roh J.H., Kim Y.H., Park D.W., Yun S.C., Lee P.H. et al., Randomized trial of stents versus bypass surgery for left main coronary artery disease: five-year outcomes of the PRECOMBAT study. Journal of the American College of Cardiology. 2015 May 26; 65(20): 2198-206. doi: 10.1016/j.jacc.2015.03.033</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Gregg W. Stone, Joseph F. Sabik, Patrick W. Serruys, et al., Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Artery Disease. N Engl J Med. 2016; 375:2223-2235</mixed-citation><mixed-citation xml:lang="en">Gregg W. Stone, Joseph F. Sabik, Patrick W. Serruys, et al., Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Artery Disease. N Engl J Med. 2016; 375:2223-2235</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Seung K.B., Park D.W., Kim Y.H. et al., Stents versus coronary-artery bypass grafting for left main coronary artery disease. New England Journal of Medicine. 2008; 358 (17):1781–1792.</mixed-citation><mixed-citation xml:lang="en">Seung K.B., Park D.W., Kim Y.H. et al., Stents versus coronary-artery bypass grafting for left main coronary artery disease. New England Journal of Medicine. 2008; 358 (17):1781–1792.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Conrotto F., Scacciatella P., D'Ascenzo F. et al., Long-term outcomes of percutaneous coronary interventions or coronary artery bypass grafting for left main coronary artery disease in octogenarians (from a Drug-Eluting stent for LefT main Artery registry substudy). American Journal of Cardiology. 2014; 113 (12): 2007–2012.</mixed-citation><mixed-citation xml:lang="en">Conrotto F., Scacciatella P., D'Ascenzo F. et al., Long-term outcomes of percutaneous coronary interventions or coronary artery bypass grafting for left main coronary artery disease in octogenarians (from a Drug-Eluting stent for LefT main Artery registry substudy). American Journal of Cardiology. 2014; 113 (12): 2007–2012.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Naganuma T., Chieffo A., Meliga E. et al., Long-term clinical outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for ostial/midshaft lesions in unprotected left main coronary artery from the DELTA registry: a multicenter registry evaluating percutaneous coronary intervention versus coronary artery bypass grafting for left main treatment. JACC: Cardiovascular Interventions. 2014; 7 (4): 354–361.</mixed-citation><mixed-citation xml:lang="en">Naganuma T., Chieffo A., Meliga E. et al., Long-term clinical outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for ostial/midshaft lesions in unprotected left main coronary artery from the DELTA registry: a multicenter registry evaluating percutaneous coronary intervention versus coronary artery bypass grafting for left main treatment. JACC: Cardiovascular Interventions. 2014; 7 (4): 354–361.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Alam M., Huang H.D., Shahzad S.A., Kar B., Virani S.S., Rogers P.A. et al. Percutaneous coronary intervention vs. coronary artery bypass graft surgery for unprotected left main coronary artery disease in the drug-eluting stents era--an aggregate data meta-analysis of 11,148 patients. Circ J. 2013; 77(2): 372-82.</mixed-citation><mixed-citation xml:lang="en">Alam M., Huang H.D., Shahzad S.A., Kar B., Virani S.S., Rogers P.A. et al. Percutaneous coronary intervention vs. coronary artery bypass graft surgery for unprotected left main coronary artery disease in the drug-eluting stents era--an aggregate data meta-analysis of 11,148 patients. Circ J. 2013; 77(2): 372-82.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Naik H., White A.J., Chakravarty T. et al., A meta-analysis of 3,773 patients treated with percutaneous coronary intervention or surgery for unprotected left main coronary artery stenosis/ JACC: Cardiovascular Interventions. 2009; 2 (8):739–747.</mixed-citation><mixed-citation xml:lang="en">Naik H., White A.J., Chakravarty T. et al., A meta-analysis of 3,773 patients treated with percutaneous coronary intervention or surgery for unprotected left main coronary artery stenosis/ JACC: Cardiovascular Interventions. 2009; 2 (8):739–747.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Valgimigli M., Malagutti P., Aoki J., Garcia-Garcia H.M., Rodriguez Granillo G.A. et al. Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis. J Am Coll Cardiol. 2006; 47: 507- 514.</mixed-citation><mixed-citation xml:lang="en">Valgimigli M., Malagutti P., Aoki J., Garcia-Garcia H.M., Rodriguez Granillo G.A. et al. Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis. J Am Coll Cardiol. 2006; 47: 507- 514.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Lee S.H., Ko Y.G., Jang Y., Kwon H.M., Lee S.H. et al. Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis. Cardiology. 2005; 104: 181-185.</mixed-citation><mixed-citation xml:lang="en">Lee S.H., Ko Y.G., Jang Y., Kwon H.M., Lee S.H. et al. Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis. Cardiology. 2005; 104: 181-185.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Lee J.Y., Park D.W., Yun S.C., Lee S.W., Kim Y.H. et al. Long-term clinical outcomes of sirolimus-versus paclitaxel-eluting stents for patients with unprotected left main coronary artery disease: analysis of the MAIN – COMPARE (Revascularization for Unprotected Left main Coronary Artery Stenosis; Comparison of Percutaneous Coronary Angioplasty Versus Surgical Revascularization) registry. J Am Coll Cardiol. 2009; 54: 853-859. 44. Mehilli J., Kastrati A., Byrne R.A., Bruskina O., Iijima R. et al. Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2009; 53: 1760-1768.</mixed-citation><mixed-citation xml:lang="en">Lee J.Y., Park D.W., Yun S.C., Lee S.W., Kim Y.H. et al. Long-term clinical outcomes of sirolimus-versus paclitaxel-eluting stents for patients with unprotected left main coronary artery disease: analysis of the MAIN – COMPARE (Revascularization for Unprotected Left main Coronary Artery Stenosis; Comparison of Percutaneous Coronary Angioplasty Versus Surgical Revascularization) registry. J Am Coll Cardiol. 2009; 54: 853-859. 44. Mehilli J., Kastrati A., Byrne R.A., Bruskina O., Iijima R. et al. Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2009; 53: 1760-1768.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Mehilli J., Richardt G., Valgimigli M., Schulz S., Singh A. et al. Zotarolimus- versus everolimus-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2013; 62: 2075-2082.</mixed-citation><mixed-citation xml:lang="en">Mehilli J., Richardt G., Valgimigli M., Schulz S., Singh A. et al. Zotarolimus- versus everolimus-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2013; 62: 2075-2082.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Прохорихин А.А, Верин В.В, Осиев А.Г, Ганюков В.И, Протопопов А.В, Демин В.В. и др. Простое слепое проспективное рандомизированное мультицентровое исследование эффективности и безопасности сиролимус-доставляющего коронарного стента «Калипсо» по сравнению с эверолимус-доставляющим стентом Xience Prime: дизайн и обоснование клинического исследования «ПАТРИОТ». Патология кровообращения и кардиохирургия. 2016; 20 (4): 96-101 Prokhorikhin A.A, Verin V.V, Osiev A.G, Ganyukov V.I, Protopopov A.V, Demin V.V. et al. Prostoe slepoe prospektivnoe randomizirovannoe mul'titsentrovoe issledovanie effektivnosti i bezopasnosti sirolimus-dostavlyayushchego koronarnogo stenta «Kalipso» po sravneniyu s everolimus-dostavlyayushchim stentom Xience Prime: dizayn i obosnovanie klinicheskogo issledovaniya «PATRIOT». Patologiya krovoobrashcheniya i kardiokhirurgiya. 2016; 20 (4): 96-101. [I Russ].</mixed-citation><mixed-citation xml:lang="en">Прохорихин А.А, Верин В.В, Осиев А.Г, Ганюков В.И, Протопопов А.В, Демин В.В. и др. Простое слепое проспективное рандомизированное мультицентровое исследование эффективности и безопасности сиролимус-доставляющего коронарного стента «Калипсо» по сравнению с эверолимус-доставляющим стентом Xience Prime: дизайн и обоснование клинического исследования «ПАТРИОТ». Патология кровообращения и кардиохирургия. 2016; 20 (4): 96-101 Prokhorikhin A.A, Verin V.V, Osiev A.G, Ganyukov V.I, Protopopov A.V, Demin V.V. et al. Prostoe slepoe prospektivnoe randomizirovannoe mul'titsentrovoe issledovanie effektivnosti i bezopasnosti sirolimus-dostavlyayushchego koronarnogo stenta «Kalipso» po sravneniyu s everolimus-dostavlyayushchim stentom Xience Prime: dizayn i obosnovanie klinicheskogo issledovaniya «PATRIOT». Patologiya krovoobrashcheniya i kardiokhirurgiya. 2016; 20 (4): 96-101. [I Russ].</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Valgimigli M., Chieffo A., Lefevre T. et al., Revisiting the incidence and temporal distribution of cardiac and sudden death in patients undergoing elective intervention for unprotected left main coronary artery stenosis in the drug eluting stent era. EuroIntervention. 2007; 2 (4): 435–443.</mixed-citation><mixed-citation xml:lang="en">Valgimigli M., Chieffo A., Lefevre T. et al., Revisiting the incidence and temporal distribution of cardiac and sudden death in patients undergoing elective intervention for unprotected left main coronary artery stenosis in the drug eluting stent era. EuroIntervention. 2007; 2 (4): 435–443.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Meliga E., Garcia-Garcia H.M., Valgimigli M. et al., Longest available clinical outcomes after drug-eluting stent implantation for unprotected left main coronary artery disease: the DELFT (Drug Eluting stent for LeFT main) Registry. Journal of the American College of Cardiology. 2008; 51 (23): 2212–2219.</mixed-citation><mixed-citation xml:lang="en">Meliga E., Garcia-Garcia H.M., Valgimigli M. et al., Longest available clinical outcomes after drug-eluting stent implantation for unprotected left main coronary artery disease: the DELFT (Drug Eluting stent for LeFT main) Registry. Journal of the American College of Cardiology. 2008; 51 (23): 2212–2219.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">De Caterina A.R., Cuculi F., Banning A.P. Incidence, predictors and management of left main coronary artery stent restenosis: a comprehensive review in the era of drug-eluting stents. EuroIntervention. 2013; 8 (11): 1326–1334.</mixed-citation><mixed-citation xml:lang="en">De Caterina A.R., Cuculi F., Banning A.P. Incidence, predictors and management of left main coronary artery stent restenosis: a comprehensive review in the era of drug-eluting stents. EuroIntervention. 2013; 8 (11): 1326–1334.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Van Mieghem C.A., Cademartiri F., Mollet N.R. et al., Multislice spiral computed tomography for the evaluation of stent patency after left main coronary artery stenting: a comparison with conventional coronary angiography and intravascular ultrasound. Circulation. 2006; 114 (7): 645–653.</mixed-citation><mixed-citation xml:lang="en">Van Mieghem C.A., Cademartiri F., Mollet N.R. et al., Multislice spiral computed tomography for the evaluation of stent patency after left main coronary artery stenting: a comparison with conventional coronary angiography and intravascular ultrasound. Circulation. 2006; 114 (7): 645–653.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Migliorini A., Valenti R., Marcucci R. et al., High residual platelet reactivity after clopidogrel loading and long-term clinical outcome after drug-eluting stenting for unprotected left main coronary disease. Circulation. 2009; 120 (22): 2214–2221.</mixed-citation><mixed-citation xml:lang="en">Migliorini A., Valenti R., Marcucci R. et al., High residual platelet reactivity after clopidogrel loading and long-term clinical outcome after drug-eluting stenting for unprotected left main coronary disease. Circulation. 2009; 120 (22): 2214–2221.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Березовская Г.А., Ганюков В.И., Карпенко М.А. Рестеноз и тромбоз внутри стента: патогенетические механизмы развития и прогностические маркеры. Российский кардиологический журнал. 2012; 6 (98): 91-95.</mixed-citation><mixed-citation xml:lang="en">Березовская Г.А., Ганюков В.И., Карпенко М.А. Рестеноз и тромбоз внутри стента: патогенетические механизмы развития и прогностические маркеры. Российский кардиологический журнал. 2012; 6 (98): 91-95.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Berezovskaya G.A., Ganyukov V.I., Karpenko M.A. Restenoz i tromboz vnutri stenta: patogeneticheskie mekhanizmy razvitiya i prognosticheskie markery. Rossiyskiy kardiologicheskiy zhurnal. 2012; 6 (98): 91-95.</mixed-citation><mixed-citation xml:lang="en">Berezovskaya G.A., Ganyukov V.I., Karpenko M.A. Restenoz i tromboz vnutri stenta: patogeneticheskie mekhanizmy razvitiya i prognosticheskie markery. Rossiyskiy kardiologicheskiy zhurnal. 2012; 6 (98): 91-95.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Feres F., Costa R.A., Abizaid A., Leon M.B., Marin-Neto J.A., Botelho R.V. et al. Three vs.Twelve Months of Dual Antiplatelet Therapy After Zotarolimus-Eluting Stents: The OPTIMIZE Randomized Trial. JAMA 2013; 310(23): 2510–2522.</mixed-citation><mixed-citation xml:lang="en">Feres F., Costa R.A., Abizaid A., Leon M.B., Marin-Neto J.A., Botelho R.V. et al. Three vs.Twelve Months of Dual Antiplatelet Therapy After Zotarolimus-Eluting Stents: The OPTIMIZE Randomized Trial. JAMA 2013; 310(23): 2510–2522.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Kim B.K., Hong M.K., Shin D.H., Nam C.M., Kim J.S., Ko Y.G. et al. A new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation). J Am Coll Cardiol. 2012; 60(15): 1340–1348.</mixed-citation><mixed-citation xml:lang="en">Kim B.K., Hong M.K., Shin D.H., Nam C.M., Kim J.S., Ko Y.G. et al. A new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation). J Am Coll Cardiol. 2012; 60(15): 1340–1348.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
