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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2017-2-65-78</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-284</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>ДИСФУНКЦИЯ РЕСПИРАТОРНОЙ СИСТЕМЫ У ПАЦИЕНТОВ С ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА ПОСЛЕ ПЛАНОВОГО ПРОВЕДЕНИЯ КОРОНАРНОГО ШУНТИРОВАНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>DYSUNCTION OF RESPIRATORY SYSTEM IN PATIENTS WITH CORONARY ARTERY DISEASE AFTER PLANNED CORONARY ARTERY BYPASS GRAFTING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баздырев</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazdyrev</surname><given-names>E. D.</given-names></name></name-alternatives><email xlink:type="simple">bazded@kemcardio.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение&#13;
 «Научно-исследовательский институт комплексных проблем&#13;
сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Scientific Institution Research Institute for Complex Issues of Cardiovascular Diseases<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>07</month><year>2017</year></pub-date><volume>0</volume><issue>2</issue><fpage>65</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баздырев Е.Д., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Баздырев Е.Д.</copyright-holder><copyright-holder xml:lang="en">Bazdyrev E.D.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/284">https://www.nii-kpssz.com/jour/article/view/284</self-uri><abstract><p>Цель исследования – проанализировать динамику показателей функции дыхания у пациентов с ишемической болезнью сердца (ИБС) и коморбидной бронхо-легочной патологией (БЛП), подвергшихся коронарному шунтированию в условиях искусственного кровообращения (ИК).Материалы и методы. Обследованы 662 пациента с ИБС, поступившие для планового проведения КШ. Формирование групп основывалось на критериях наличия БЛП и бронхообструктивного типа вентиляционных нарушений. В 1-ю группу включены 48 (7,2%) больных с БЛП без обструктивных нарушений, во 2-ю − 248 (37,5%) пациентов с БЛП, имеющих обструкцию дыхательных путей; в 3-ю − 366 (55,3%) пациентов с изолированной ИБС. Анализ динамики функции респираторной системы основывался на отклонении от должных значений, а также на отклонении перекодированных параметров дыхания, составляющих основу комплексной оценки функции легких.Результаты. В послеоперационном периоде у всех пациентов наблюдалось снижение всех параметров дыхания. Статистически более низкие параметры наблюдались у пациентов, имевших бронхообструктивный синдром. В большей степени (более чем на 15% от исходных показателей) регистрировалось снижение форсированной и медленной жизненной емкости легких, общей емкости легких, объема форсированного выдоха за 1-ю секунду, а также диффузионной способности, в меньшей степени – внутригрудного и остаточного объемов. При сравнении аналогичных параметров дыхания основываясь на их перекодировке статистически выраженное снижение наблюдалось у пациентов, имевших заболевание респираторной системы (1-й и 2-й группы) в сравнении с пациентами с изолированной ИБС.Заключение. После проведения КШ в условии ИК отмечается снижение всех показателей, характеризующих функцию легких, более выраженное снижение отмечалось по уровню форсированной и медленной жизненной емкости легких и объеме форсированного выдоха за 1-ю секунду. Интерпретация динамического изменения перекодированных показателей показала преимущество перед традиционным анализом, основанном на отклонении от должных значений.</p></abstract><trans-abstract xml:lang="en"><p>The purpose. Analysis of the dynamics of respiratory function indicators in patients with coronary artery disease (CAD) and comorbid bronchopulmonary pathology (BPP) who underwent coronary artery bypass grafting under cardiopulmonary bypass (CB).Materials and methods. We examined 662 patients with CAD admitted for planned CABG. The formation of groups was based on the presence criteria of BPP and broncho-obstructive type of ventilatory disorders. Group 1 included 48 (7.2%) patients with BPP without obstructive disorders, group 2 – 248 (37.5%) patients with BPP who have respiratory obstruction, group 3 – 366 (55.3%) patients with the isolated CAD. The analysis of the dynamics of respiratory system function was based on the deviation from the due values as well as on the deviation of recoded respiratory parameters, which form the basis of comprehensive assessment of respiratory function.Results. In the postoperative periodall the patients showed a decrease of all respiratory parameters. Statisticallylower parameters were observed in patients who had broncho-obstructive syndrome. To a greater extent (for more than 15% from the baseline) we registered a decrease in forced and slow vital lung capacity, total lung capacity, forced expiratory volume in 1 second, as well as diffusing capacity, to a lesser extent –intrathoracic and residual volumes. When comparing the similar respiratory parameters, basing on their recoding, statistically marked decrease was observed in patients who had a respiratory disease (the 1st and the 2nd groups) as compared to the patients with isolated CAD.Conclusion. After CABG under CB there was a decrease of all the indicators which characterize pulmonary function, a more pronounced decrease was noticed in the level of forced and slow vital lung capacity and forced expiratory volume in 1 second. Interpretation of the dynamic changes of the recoded indicators showed an advantage over the traditional analysis based on the deviation from the due values.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коморбидная патология</kwd><kwd>функция легких</kwd><kwd>комплексная оценка респираторной функции</kwd><kwd>коронарное шунтирование</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>хроническая обструктивная болезнь легких</kwd></kwd-group><kwd-group xml:lang="en"><kwd>comorbid pathology</kwd><kwd>pulmonary function</kwd><kwd>comprehensive assessment of respiratory function</kwd><kwd>coronary artery bypass grafting</kwd><kwd>coronary artery disease</kwd><kwd>chronic obstructive pulmonary disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Roncada G., Dendale P., Linsen L., Hendrikx M., Hansen D. 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