References

kpccz

Комплексные проблемы сердечно-сосудистых заболеваний

Complex Issues of Cardiovascular Diseases

2306-12782587-9537

Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”

10.17802/2306-1278-2014-1-67-74

kpccz-31

Research Article

КЛИНИЧЕСКАЯ МЕДИЦИНА

CLINICAL MEDICINE

ЛЕЧЕНИЕ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ ПОД КОНТРОЛЕМ КОНЦЕНТРАЦИИ НАТРИЙУРЕТИЧЕСКИХ ПЕПТИДОВ

HEART FAILURE TREATMENT UNDER CONTROL OF NATRIURETIC PEPTIDES CONCENTRATION

Барбараш

О. Л.

Barbarash

O. L.

Усольцева

Е. Н.

Usoltseva

E. N.

кандидат медицинских наук

научный сотрудник лаборатории патофизиологии

Адрес для переписки:650002, г. Кемерово, Сосновый бульвар, д. 6. Тел: 8(3842) 64-33-67

PhD

research associate of pathophysiology laboratory

Correspondence address:6, Sosnoviy blvd., Kemerovo, 650002. Tel.: +7 (3842) 64-33-67

usen84@yandex.ru

Федеральное государственное бюджетное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» Сибирского отделения Российской академии медицинских наук, КемеровоРоссияFederal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Medical Sciences, KemerovoRussian Federation

2014

28062015

016774

2015

Барбараш О.Л., Усольцева Е.Н.

Barbarash O.L., Usoltseva E.N.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.nii-kpssz.com/jour/article/view/31

Натрийуретические пептиды (НУП) являются важными биомаркерами в диагностике и определении прогноза у пациентов с сердечной недостаточностью (СН). Оценка динамики концентрации НУП (BNP, NT-proBNP) может быть использована в качестве критерия успешности проводимой терапии. Так, при достижении целевых уровней НУП можно прогнозировать благоприятный исход заболевания. В настоящее время лечение СН с учетом уровней НУП является частью рекомендаций по лечению СН (класс IIа) и улучшению ее исхода (класс IIб) в США, однако такой подход не используется в российских клиниках.

Цель. Представить современный взгляд на возможность использования НУП для оценки эффективности проводимой терапии пациентов с СН.

Natriuretic peptides (NUP) are important biomarkers in the diagnostics and determining of prognosis in patients with heart failure (HF). Evaluation of NUP (BNP, NT-proBNP) dynamics can be used as a success criterion of the ongoing therapy. Thus when reaching the target levels of NUP, a favourable disease outcome can be predicted. At the present time HF treatment with account of NUP levels is a part of HF treatment recommendations (class IIа) and improvement of its outcome (class IIb) in the USA; currently, this approach is not implemented in Russian hospitals.

Purpose. To present a modern understanding of the use of NUP levels in the assessment of therapy efficacy in patients with HF.

натрийуретические пептидысердечная недостаточностьоценка эффективности терапии

natriuretic peptidesheart failuretreatment efficacy evaluation

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The authors declare that there are no conflicts of interest present.