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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2017-6-4-121-128</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-344</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИТИЧЕСКИЙ ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYTICAL REVIEW</subject></subj-group></article-categories><title-group><article-title>МОДУЛЯЦИЯ СЕРДЕЧНОЙ СОКРАТИМОСТИ ДЛЯ ЛЕЧЕНИЯ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ</article-title><trans-title-group xml:lang="en"><trans-title>CARDIAC CONTRACTILITY MODULATION FOR TREATMENT OF CHRONIC HEART FAILURE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>O. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хоменко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khomenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамчур</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamchur</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мамчур Сергей Евгеньевич.</p><p>650002, Кемерово, Сосновый бульвар, д. 6, 8 (3842) 64-35-38</p></bio><bio xml:lang="en"><p>Mamchur Sergey.</p><p>6, Sosnoviy blvd., Kemerovo, 650002, +7 (3842) 64-35-38</p></bio><email xlink:type="simple">mamchse@kemcardio.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чичкова</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Chichkova</surname><given-names>T. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>01</day><month>12</month><year>2017</year></pub-date><volume>6</volume><issue>4</issue><fpage>121</fpage><lpage>128</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебедева О.Ю., Хоменко Е.А., Мамчур С.Е., Чичкова Т.Ю., Романова М.П., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Лебедева О.Ю., Хоменко Е.А., Мамчур С.Е., Чичкова Т.Ю., Романова М.П.</copyright-holder><copyright-holder xml:lang="en">Lebedeva O.Y., Khomenko E.A., Mamchur S.E., Chichkova T.Y., Romanova M.P.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/344">https://www.nii-kpssz.com/jour/article/view/344</self-uri><abstract><p>В обзорной статье описываются современные представления о роли фосфоламбана в регуляции активности АТФ-зависимого кальциевого насоса и сокращения кардиомиоцитов, возможностях влияния на данные процессы модуляции сердечной сократимости нового метода лечения хронической сердечной недостаточности.</p></abstract><trans-abstract xml:lang="en"><p>The review article describes the current role of phospholambane in the regulation of ATP-dependent calcium pump activity and the number of cardiomyocytes, and the possibilities of cardiac contractility modulation as a novel method for treatment of chronic heart failure.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечная недостаточность</kwd><kwd>имплантируемые устройства</kwd><kwd>модуляция сердечной сократимости</kwd></kwd-group><kwd-group xml:lang="en"><kwd>heart failure</kwd><kwd>implantable devices</kwd><kwd>cardiac contractility modulation</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>СО РАН, комплексная программа фундаментальных научных исследований</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ho K.K., Pinsky J.L., Kannel W.B., Levy D. 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