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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2018-7-4S-118-122</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-515</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE STUDY</subject></subj-group></article-categories><title-group><article-title>Многократное использование биопротезов в хирургии рецидивного митрального порока. Клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of repeat tissue valve replacement for recurrent mitral valve disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стасев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Stasev</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Стасев Александр Николаевич - кандидат медицинских наук, научный сотрудник лаборатории кардиоваскулярного биопротезирования.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Stasev Alexander N. - PhD, researcher at the Laboratory of Bioprosthetic Replacement.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><email xlink:type="simple">astasev@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Одаренко</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Odarenko</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Одаренко Юрий Николаевич - кандидат медицинских наук, заведующий лабораторией кардиоваскулярного биопротезирования.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Odarenko Yuri N. - MD, PhD, the Head of the Laboratory of Bioprosthetic Replacement.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кокорин</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokorin</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кокорин Станислав Геннадьевич - кандидат медицинских наук, ведущий научный сотрудник лаборатории кардиоваскулярного биопротезирования.</p></bio><bio xml:lang="en"><p>Kokorin Stanislav G. - PhD, Leading Researcher the Laboratory of Bioprosthetic Replacement.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рутковская</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rutkovskaya</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рутковская Наталья Витальевна - доктор медицинских наук, старший научный сотрудник лаборатории кардиоваскулярного биопротезирования НИИКПССЗ, заведующая отделением неотложной кардиологии № 2 КОККД им. академика Л.С. Барбараша.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Rutkovskaya Natalia V. - PhD, senior researcher at the Laboratory of Bioprosthetic Replacement.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левадин</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Levadin</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левадин Юрий Владимирович - врач сердечно-сосудистый хирург кардиохирургического отделения.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Levadin Yurij V. - cardiovascular surgeon at the Cardiac Surgery Department.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Барбараш Леонид Семенович - доктор медицинских наук, профессор, академик РАН, главный научный сотрудник НИИКПССЗ, главный специалист КОККД им. академика Л.С. Барбараша.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Barbarash Leonid S. - PhD, Professor, Academician of the Russian Academy of Sciences, Chief Researcher.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний; Государственное бюджетное учреждение здравоохранения Кемеровской области Кемеровский областной клинический кардиологический диспансер имени академика Л.С. Барбараша<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases; State Budgetary Healthcare Institution of the Kemerovo Region Kemerovo Regional Clinical Cardiology Dispensary n.a. Academician L.S. Barbarash<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>02</day><month>02</month><year>2019</year></pub-date><volume>7</volume><issue>4S</issue><fpage>118</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Стасев А.Н., Одаренко Ю.Н., Кокорин С.Г., Рутковская Н.В., Левадин Ю.В., Барбараш Л.С., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Стасев А.Н., Одаренко Ю.Н., Кокорин С.Г., Рутковская Н.В., Левадин Ю.В., Барбараш Л.С.</copyright-holder><copyright-holder xml:lang="en">Stasev A.N., Odarenko Y.N., Kokorin S.G., Rutkovskaya N.V., Levadin Y.V., Barbarash L.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/515">https://www.nii-kpssz.com/jour/article/view/515</self-uri><abstract><p>Представлен клинический случай наблюдения успешного многократного повторного хирургического лечения пациентки 65 лет с рецидивным пороком митрального клапана. Использование биологических протезов при лечении приобретенного порока сердца позволило исключить в послеоперационном периоде антикоагулянтную терапию. В то же время использование новых хирургических методов лечения (методика протез-в-протез) способствовало значительному снижению риска хирургических осложнений во время проведения третьей операции. Таким образом, использование биологических протезов, своевременная диагностика дисфункции клапанов, а также использование риск-снижающих технологий позволяют получить удовлетворительный результат лечения, продлить и улучшить качество жизни пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The clinical case reports the experience of successful repeat surgical treatment of a 65-year-old patient with recurrent mitral valve disease. The use of tissue valve prostheses in the treatment of acquired heart disease allowed avoiding anticoagulant therapy in the postoperative period. In addition, the use of new surgical methods of treatment (valve-in-valve technique) contributed to a significant reduction in the risk of surgical complications during the third heart valve replacement. Thus, the use of tissue heart valves, timely diagnosis of valve dysfunction, as well as the use of novel technologies which allows reducing the risk ensure achieving optimal outcome, extending and improving the quality of life of the patient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>многократное репротезирование</kwd><kwd>митральный клапан</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>multiple redo</kwd><kwd>operation</kwd><kwd>mitral valve</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vohra H.A., Whistance R.N., Roubelakis A., Burton A., Barlow C.W., Tsang G.M., Livesey S.A., Ohri S.K. 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