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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2019-8-1-70-79</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-532</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИТИЧЕСКИЙ ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYTICAL REVIEW</subject></subj-group></article-categories><title-group><article-title>СЛОЖНОСТИ В ДИАГНОСТИКЕ ОБСТРУКТИВНЫХ ПОРАЖЕНИЙ КОРОНАРНЫХ АРТЕРИЙ: РОЛЬ НЕИНВАЗИВНЫХ ТЕСТОВ</article-title><trans-title-group xml:lang="en"><trans-title>CHALLENGES OF DIAGNOSIS OF OBSTRUCTIVE CORONARY ARTERY DISEASE: THE ROLE OF NON-INVASIVE TESTING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корок</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korok</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, научный сотрудник лаборатории патологии кровообращения отдела мультифокального атеросклероза,</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>PhD, researcher at the Laboratory of Blood Circulation Pathology, Department of Multivessel and Polyvascular Disease, </p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сумин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sumin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующий отделом мультифокального атеросклероза,</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>PhD, Head of the Department of Multivessel and Polyvascular Disease,</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2019</year></pub-date><volume>8</volume><issue>1</issue><fpage>70</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корок Е.В., Сумин А.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Корок Е.В., Сумин А.Н.</copyright-holder><copyright-holder xml:lang="en">Korok E.V., Sumin A.N.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/532">https://www.nii-kpssz.com/jour/article/view/532</self-uri><abstract><p>Высокая смертность от сердечно-сосудистых заболеваний и особенно от ишемической болезни сердца (ИБС) является одной из причин больших затрат системы здравоохранения. Тенденцией последних лет в России является увеличение числа диагностических коронароангиографий (КАГ). Однако в реальной клинической практике у значительного числа больных инвазивная КАГ не выявляет обструктивных поражений коронарных артерий (КА). В регистровых исследованиях частота интактных КА достигает 42%, в анализе данных нашей клиники – 37,9%. Возникает парадоксальная ситуация: несмотря на совершенствование диагностических алгоритмов обследования больных с подозрением на ИБС, отраженных в соответствующих международных и национальных рекомендациях, доступность современных неинвазивных методов диагностики, это никак не влияет на частоту выявления обструктивных поражений КА при КАГ. Оптимальный алгоритм выявления значимых поражений КА является предметом оживленных дискуссий, а имеющиеся рекомендации содержат много противоречий. В предлагаемом обзоре подробно рассматриваются разночтения, касающиеся не только оценки предтестовой вероятности, но и предлагаемых неинвазивных тестов. В том числе обсуждается приоритетное использование неинвазивных тестов с анатомической оценкой (то есть мультиспиральной компьютерной томографии коронарных артерий), а не функциональных тестов с визуализацией. Данный обзор будет способствовать лучшему пониманию диагностических стратегий при стабильной ИБС как в научных исследованиях, так и в клинической практике.</p></abstract><trans-abstract xml:lang="en"><p>High mortality from cardiovascular diseases, especially coronary artery disease (CAD), represents a major economic burden on healthcare systems. The number of diagnostic coronary angiographies (CAG) is increasing in the Russian Federation. However, routine invasive CAG is not able to determine obstructive coronary artery disease in a considerable number of patients. The rate of intact coronary arteries reaches 42% in the major registries and accounts for 37.9% in our Research Institute. Despite all improvements in the diagnostic algorithms focused on suspected coronary artery disease, stated in the recent international and national guidelines, and the availability of advanced non-invasive diagnostic methods, they do not improve accurate CAG diagnosis of obstructive coronary artery disease. Moreover, the available guidelines contain many contradictions. Therefore, an optimal diagnostic algorithm of significant coronary artery lesions is a subject of discussion. The proposed review discusses all discrepancies concerning the assessment of the pretest probability as well as the proposed non-invasive testing. In addition, the preferred use of non-invasive tests with anatomical assessment (i.e. multispiral computed tomography coronary imaging) rather than functional tests with visualization is stated. This review ensures better understanding of diagnostic strategies for stable coronary artery disease used both in researches and in clinical practice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>диагностика</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>неинвазивные тесты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diagnosis</kwd><kwd>coronary artery disease</kwd><kwd>non-invasive tests</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fihn S.D., Gardin J.M., Abrams J., Berra K., Blankenship J.C., Dallas A.P. et al. 2012 ACCF/AHA/ACP/AATS/PCNA/ SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. 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