kpcczКомплексные проблемы сердечно-сосудистых заболеванийComplex Issues of Cardiovascular Diseases2306-12782587-9537Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”10.17802/2306-1278-2019-8-4-145-152kpccz-640Research ArticleАНАЛИТИЧЕСКИЙ ОБЗОР. Анестезиология и реаниматологияREVIEWS. Anaesthesiology and intensive careВлияние компонентов общей анестезии на системный воспалительный ответ при кардиохирургических вмешательствахEffects of general anesthesia on systemic inflammatory response during cardiac surgery with extracorporeal circulationАджигалиевР. Р.AdzhigalievR. R.

Аджигалиев Руслан Рафаэлевич - врач высшей категории, анестезиолог-реаниматолог отделения анестезиологии-реаниматологии.

Ул. Покровская Роща, 4, Астрахань, 414011; тел. +7 (8512) 478-518, +7 (960) 851-25-10

Ruslan R. - anesthesiologist and intensivist at the Intensive Care Unit.

4, Pokrovskaya Roscha St., Astrakhan, 414011; phones +7 (8512) 478-518, +7 (960) 851-25-10

adgigaliev@gmail.comБаутинА. Е.BautinA. E.

Баутин Андрей Евгеньевич - заведующий научно-исследовательской лабораторией анестезиологии и реаниматологии, профессор кафедры анестезиологии и реаниматологии, доктор медицинских наук, доцент, врач высшей категории.

Ул. Аккуратова, д. 2, Санкт-Петербург, 197341

Bautin Andrei E. - PhD, Head of the Intensive Care Research Laboratory, Associate Professor at the Department of Intensive Care.

2, Akkuratova St., St. Petersburg, 197341

ПасюгаВ. В.PasyugaV. V.

Пасюга Вадим Владимирович - заведующий отделения анестезиологии-реаниматологии, кандидат медицинских наук, врач высшей категории.

Ул. Покровская Роща, 4, Астрахань, 414011

Pasyuga Vadim V. - PhD, Head of the Intensive Care Unit

4, Pokrovskaya Roscha St., Astrakhan, 414011

Федеральное государственное бюджетное учреждение «Федеральный центр сердечно-сосудистой хирургии» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution “Federal Center for Cardiovascular Surgery” of the Ministry of Healthcare of the Russian FederationRussian FederationФедеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В.А. Алмазова» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution “Almazov National Medical Research Centre” of the Ministry of Healthcare of the Russian FederationRussian Federation20192512201984145152Copyright © Аджигалиев Р.Р., Баутин А.Е., Пасюга В.В., 20192019Аджигалиев Р.Р., Баутин А.Е., Пасюга В.В.Adzhigaliev R.R., Bautin A.E., Pasyuga V.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.nii-kpssz.com/jour/article/view/640

Системный воспалительный ответ (СВО) является грозным осложнением хирургических вмешательств, увеличивающий заболеваемость и смертность пациентов. Известно, что анестетики обладают способностью влиять на иммунную систему и проявление СВО. Знание механизмов подобного влияния является клинически важным условием правильного выбора и применения анестетика с целью снижения проявления СВО и инфекционных осложнений в послеоперационном периоде.

Systemic inflammatory response syndrome (SIRS) is a severe complication in surgical patients associated with increased morbidity and mortality. Anesthetics are known to produce certain effects on the immune system and the manifestation of SIRS. The understanding of these beneficial mechanisms allows selecting optimal anesthetics in order to reduce the manifestation of SIRS and infectious complications in the postoperative period.

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The authors declare that there are no conflicts of interest present.