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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2019-8-4S-95-103</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-654</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Сердечно-сосудистая хирургия</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiovascular surgery</subject></subj-group></article-categories><title-group><article-title>Механическая тромбэктомия при остром ишемическом инсульте: опыт одного центра</article-title><trans-title-group xml:lang="en"><trans-title>Mechanical thrombectomy in acute ischemic stroke: a single-center experience</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ваккосов</surname><given-names>К. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vakkosov</surname><given-names>K. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ваккосов Камолиддин Мухаммедович - младший научный сотрудник лаборатории интервенционных методов диагностики и лечения отдела мультифокального атеросклероза Федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», врач кабинета рентгенохирургических методов диагностики и лечения Государственного бюджетного учреждения здравоохранения Кемеровской области «Кемеровский областной клинический кардиологический диспансер имени академика Л.С. Барбараша».</p><p>650002, г. Кемерово, Сосновый бульвар, 6</p></bio><bio xml:lang="en"><p>Vakkosov Kamoliddin M. - research assistant, Laboratory of Interventional Cardiology at the Multifocal atherosclerosis Department, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, interventional cardiologist at the State Budgetary Healthcare Institution of the Kemerovo Region “Kemerovo Regional Clinical Cardiology Dispensary n.a. academician L.S. Barbarash”.</p><p>650002, Kemerovo, 6, Sosnoviy Blvd.</p></bio><email xlink:type="simple">5758999@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наумов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Naumov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наумов Данил Юрьевич - лаборант-исследователь лаборатории интервенционных методов диагностики и лечения отдела мультифокального атеросклероза Федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», врач кабинета рентгенохирургических методов диагностики и лечения Государственного бюджетного учреждения здравоохранения Кемеровской области «Кемеровский областной клинический кардиологический диспансер имени академика Л.С. Барбараша».</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Naumov Danil Yu., interventional cardiology cabinet X-ray surgical method of diagnostic and treatment Kemerovo State Budgetary Healthcare Institution “Kemerovo Regional Clinical Cardiac Dispensary n.a. academician L.S. Barbarash”, research assistant at the laboratory of interventional method of diagnostic and treatment Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”.</p><p>6, Sosonoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Водопьянова</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vodop`yanova</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Водопьянова Нина Ивановна - младший научный сотрудник лаборатории нейрососудистой патологии отдела мультифокального атеросклероза Федерального государственного бюджетного научного учреждения «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний», врач-невролог неврологического отделение для больных с ОНМК Государственного бюджетного учреждения здравоохранения Кемеровской области «Кемеровский областной клинический кардиологический диспансер имени академика Л.С. Барбараша».</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>6, Sosonoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Молдавская</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moldavskaya</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Молдавская Ирина Валерьевна - кандидат медицинских наук, заведующая неврологическим отделением для лечения пациентов с ОНМК.</p></bio><bio xml:lang="en"><p>Moldavskaya Irina V. - PhD, neurologist and Head of the Neurology Department.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ганюков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ganyukov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ганюков Владимир Иванович - доктор медицинских наук, заведующий лабораторией интервенционных методов диагностик и лечения отдела мультифокального атеросклероза.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Ganyukov Vladimir I. - PhD, Head of the Laboratory of Interventional Cardiology.</p><p>6, Sosonoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»; Государственное бюджетное учреждение здравоохранения Кемеровской области «Кемеровский областной клинический кардиологический диспансер имени академика Л.С. Барбараша»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”; State Budgetary Healthcare Institution of the Kemerovo Region “Kemerovo Regional Clinical Cardiology Dispensary named after academician L.S. Barbarash”<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Государственное бюджетное учреждение здравоохранения Кемеровской области «Кемеровский областной клинический кардиологический диспансер имени академика Л.С. Барбараша»<country>Россия</country></aff><aff xml:lang="en">State Budgetary Healthcare Institution of the Kemerovo Region “Kemerovo Regional Clinical Cardiology Dispensary named after academician L.S. Barbarash”<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>01</month><year>2020</year></pub-date><volume>8</volume><issue>4S</issue><fpage>95</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ваккосов К.М., Наумов Д.Ю., Водопьянова Н.И., Молдавская И.В., Ганюков В.И., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ваккосов К.М., Наумов Д.Ю., Водопьянова Н.И., Молдавская И.В., Ганюков В.И.</copyright-holder><copyright-holder xml:lang="en">Vakkosov K.M., Naumov D.Y., Vodop`yanova N.I., Moldavskaya I.V., Ganyukov V.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/654">https://www.nii-kpssz.com/jour/article/view/654</self-uri><abstract><sec><title>Цель</title><p>Цель. Проанализировать результаты собственного опыта эндоваскулярного лечения острого ишемического инсульта (ОИИ) в контексте современных литературных данных.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. B анализ вошли 12 пациентов с ОИИ, пролеченных на базе Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» г. Кемерово. Всем пациентам выполнена механическая тромбэктомия стент-ретривером «Trevo». Показатели и конечные точки: (1) Хороший клинический результат по шкале Ренкина (mRS≤2), (2) уровень достижения эффекта первого прохождения, (3) уровень достижения кровотока 2b-3/3 по шкале TICI, (4) частота осложнений и (5) летальность через 90 дней.</p></sec><sec><title>Результаты</title><p>Результаты. Большинство были мужского пола (66,7%), и в возрасте 59,5 лет [57,5; 66,5]. У всех установлен диагноз гипертоническая болезнь, 8 (61,5%) имели в анамнезе ишемической болезни сердца, в 7 (53,8%) случаях отмечен факт курения, нарушения ритма и проводимости. Тяжесть по шкале NIHSS составила – 13 баллов, инвалидизация по шкале Ренкина 4–5 степени – 75%. В 33,3% случаях выявлено тандемное поражение артерии каротидного бассейна и 25% потребовало стентирование сонной артерии. Клинический хороший результат (mRS≤2) через 90 дней достигнут в 77,8% (7/9) среди выживших пациентов. Тяжесть по шкале NIHSS – 4 [1; 5]. Эффект первого прохождения в выборке достигнут у 50% пациентов. Уровень достижения кровотока mTICI 2b-3/3 составил 91,7%. 90 дневная летальность – 25%.</p></sec><sec><title>Заключение</title><p>Заключение. Механическая тромбэктомия с использованием стент-ретривера демонстрирует убедительные клинические результаты в небольшой когорте пациентов с ОИИ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. Mechanical thrombectomy is standard of care for the treatment of acute ischemic stroke. The objective of this study is to analyze the results of our own experience of endovascular treatment in Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases” Kemerovo.</p></sec><sec><title>Methods</title><p>Methods. 12 patients with AIS and underwent mechanical thrombectomy with «Trevo» stent-retriever were included in this analysis. Primary outcomes included 90-day modified Rankin scale (mRS) score, first pass effect (FPE) and recanalization rate (TICI score), the combined incidence of postintervention hemorrhages and mortality at 90 days.</p></sec><sec><title>Results</title><p>Results. Among 12 patients (66.7% male, age 59.5 [57.5; 66.5] years) hypertension were in 100%, 61.5% had an ischemic heart disease, 53.8% was current smoking and atrial fibrillation. Median of the NIHSS scale was 13 points, mRS≥4 was in 75% of patients. In 33.3% was a tandem lesion (internal carotid artery terminus and middle cerebral artery) and 25% required stenting of the carotid artery. Good clinical outcomes (mRS≤2 at 90 days) were achieved in 77.8% (7/9) among surviving patients. The 90-day NIHSS score – 4 [1; 5]. The first pass effect and recanalization rate (TICI Scores 2b-3/3) was achieved in 50% and 91.7% of patients. The combined incidence of postintervention hemorrhages and mortality at 90 days was 33.3% and 25% respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Despite the small sample size, stent retriever mechanical thrombectomy in AIS provides satisfactory clinical results.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>механическая тромбэктомия</kwd><kwd>стент-ретривер</kwd><kwd>острый ишемический инсульт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thrombectomy</kwd><kwd>stent retriever</kwd><kwd>acute ischemic stroke</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Berkhemer O., Fransen P., Beumer D., et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015 Jan 1;372(1):11-20. doi:10.1056/NEJMoa1411587.</mixed-citation><mixed-citation xml:lang="en">Berkhemer O., Fransen P., Beumer D., et al. A randomized trial of intraarterial treatment for acute ischemic stroke. 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