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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2020-9-3-108-117</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-762</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group></article-categories><title-group><article-title>Рентгенологические аспекты диагностики церебральной гиперперфузии. Лекция</article-title><trans-title-group xml:lang="en"><trans-title>Radiological aspects of cerebral hyperperfusion syndrome diagnosis. Lecture</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1827-606X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенов</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenov</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, ведущий научный сотрудник лаборатории лучевых методов диагностики отдела клинической кардиологии,</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>PhD, leading researcher at the Laboratory for Radiology and Tomography Diagnosis, </p><p>6, Sosonoviy Blvd., Kemerovo, 650002</p></bio><email xlink:type="simple">dr_semenov_s@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2835-7779</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Короткевич</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotkevich</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-радиолог,</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>radiologist,</p><p>6, Sosonoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7573-0636</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, заведующий лабораторией лучевых методов диагностики отдела клинической кардиологии,</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>PhD, Head of the Laboratory for Radiology and Tomography Diagnosis,</p><p>6, Sosonoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2020</year></pub-date><volume>9</volume><issue>3</issue><fpage>108</fpage><lpage>117</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенов С.Е., Короткевич А.А., Коков А.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Семенов С.Е., Короткевич А.А., Коков А.Н.</copyright-holder><copyright-holder xml:lang="en">Semenov S.E., Korotkevich A.A., Kokov A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/762">https://www.nii-kpssz.com/jour/article/view/762</self-uri><abstract><p>Рассмотрены аспекты лучевой диагностики гиперперфузии головного мозга после реваскуляризирующих операций на каротидных и коронарных артериях, а также при инсульте.</p><p>Наиболее часто в клинической практике неврологов и нейрорадиологов предметом беспокойства является гипоперфузия, но и гиперперфузия имеет немаловажное клиническое и прогностическое значение. Острая патологическая гиперперфузия, встречающаяся после каротидной эндартерэктомии, а также при венозном инсульте вследствие церебрального венозного синустромбоза с двух- и трехкратным увеличением регионарного мозгового кровотока характеризуется высоким риском кровоизлияния. Более благоприятным состоянием является доброкачественная гиперперфузия с умеренным (до 30%) полнокровием, развивающаяся при венозном инсульте и являющаяся элементом патогенеза застойного повреждения ткани мозга с вторичной ишемией. У больных, перенесших коронарные шунтирования или симультанные операции на сонных и венечных артериях, в раннем послеоперационном периоде нередко отмечается негативная динамика неврологического статуса как проявление реперфузионного синдрома в виде умеренной постишемической гиперперфузии. Своевременная диагностика этих состояний может предотвратить тяжелые осложнения церебрального синустромбоза, а также неблагоприятные события послеоперационного периода у пациентов с поражением коронарных и каротидных артерий. Перфузионная компьютерная томография является наиболее быстрым, адаптированным к неотложной диагностике методом исследования. Однофотонная эмиссионная компьютерная томография обеспечивает неинвазивную оценку перфузии и метаболического статуса ткани головного мозга при меньших лучевой нагрузке и риске побочных действий, включая аллергические реакции.</p></abstract><trans-abstract xml:lang="en"><p>Several aspects of diagnostic radiology are considered, particularly concerning the occurrence of stroke and cerebral hyperperfusion after carotid and coronary artery revascularization.</p><p>Hypoperfusion is the main subject of concern for neurologists and neuroradiologists in the clinical practice, even though hyperperfusion also has an important clinical and prognostic value. Acute pathological hyperperfusion after carotid endarterectomy and venous stroke following cerebral venous sinus thrombosis with a two- or three-fold increase in regional cerebral blood flow have a high risk of hemorrhage. A more favorable condition is benign hyperperfusion with moderate (up to 30%) plethora. It develops during venous stroke as element of the pathogenesis of brain tissue injury after secondary ischemia. Often patients who have undergone the simultaneous carotid and coronary surgery or CABG in the early postoperative period showed signs of neurological deterioration in the form of moderate postischemic hyperperfusion. Timely diagnosis can prevent severe cerebral complications during cerebral venous sinus thrombosis or postoperative adverse events in patients with coronary and carotid artery injuries. CT perfusion is the fastest and most adapted tool for emergency diagnostics, whereas SPECT provides a non-invasive assessment of perfusion and brain tissue metabolism with less radiation and fewer negative effects, such as allergic reactions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>компьютерная томография</kwd><kwd>однофотонная эмиссионная компьютерная томография</kwd><kwd>гиперперфузия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>CT</kwd><kwd>SPECT</kwd><kwd>CBF</kwd><kwd>CBV</kwd><kwd>MTT</kwd><kwd>TTP</kwd><kwd>Hyperperfusion</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы выражают признательность Ю.М. 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