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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2021-10-1-65-72</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-814</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Показания к коронарошунтографии в раннем послеоперационном периоде аортокоронарного шунтирования</article-title><trans-title-group xml:lang="en"><trans-title>Indications to coronary artery bypass graft angiography in the early postoperative period</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1011-2300</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семагин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Semagin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семагин Алексей Андреевич - кандидат медицинских наук, сердечно-сосудистый хирург кардиохирургического отделения № 2 ФЦССХ МЗ РФ; ассистент кафедры хирургии института дополнительного профессионального образования ЮУГМУ МЗ РФ.ул. Воровского, 64, Челябинск, 454092; пр. Героя России Родионова Е.Н., 2, Челябинск, 454003.</p></bio><bio xml:lang="en"><p>Semagin Aleksey A. - M.D., Ph.D., a cardiovascular surgeon at the Cardiac Surgery Department No. 2, Federal Centre for Cardiovascular Surgery; an assistant at the Department of Surgery, Institute of Vocational Education, South Ural State Medical University.64, Vorovskogo St., Chelyabinsk, 454092; 2, Hero of Russia Rodionova E.N. ave., Chelyabinsk, 454003.</p></bio><email xlink:type="simple">AASemagin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3162-1523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукин</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukin</surname><given-names>O. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лукин Олег Павлович - доктор медицинских наук, профессор кафедры госпитальной хирургии ЮУГМУ МЗ РФ; главный врач ФЦССХ МЗ РФ.ул. Воровского, 64, Челябинск, 454092; пр. Героя России Родионова Е.Н., 2, Челябинск, 454003.</p></bio><bio xml:lang="en"><p>Lukin Oleg P. - M.D., Ph.D., Professor at the Department of Hospital Surgery, South Ural State Medical University; chief physician at the Federal Centre for Cardiovascular Surgery.64, Vorovskogo St., Chelyabinsk, 454092; 2, Hero of Russia Rodionova E.N. ave., Chelyabinsk, 454003.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7806-2357</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фокин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fokin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фокин Алексей Анатольевич - доктор медицинских наук, профессор, заведующий кафедрой хирургии института дополнительного профессионального образования.ул. Воровского, 64, Челябинск, 454092.</p></bio><bio xml:lang="en"><p>Fokin Aleksey A. - Ph.D., Professor, the Head of the Department of Surgery, Institute of Vocational Education, South Ural State Medical University.64, Vorovskogo St., Chelyabinsk, 454092.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Южно-Уральский государственный медицинский университет Министерства здравоохранения Российской Федерации; Федеральный центр сердечно-сосудистой хирургии Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">South Ural State Medical University; Federal Centre for Cardiovascular Surgery<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Южно-Уральский государственный медицинский университет Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">South Ural State Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>23</day><month>03</month><year>2021</year></pub-date><volume>10</volume><issue>1</issue><fpage>65</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семагин А.А., Лукин О.П., Фокин А.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Семагин А.А., Лукин О.П., Фокин А.А.</copyright-holder><copyright-holder xml:lang="en">Semagin A.A., Lukin O.P., Fokin A.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/814">https://www.nii-kpssz.com/jour/article/view/814</self-uri><abstract><p>Цель. Определение показаний к проведению неотложной коронарошунтографии (КШГ) после аортокоронарного шунтирования. Материалы и методы. Проведен ретроспективный анализ данных 7 616 пациентов с ишемической болезнью сердца, которым в ФГБУ «ФЦССХ» Минздрава России (г. Челябинск) с 2012 по 2019 г. выполнено изолированное аортокоронарное шунтирование. Проанализированы все пациенты, подвергшиеся неотложной КШГ в связи с появлением в раннем послеоперационном периоде признаков повреждения миокарда (n = 103; 1,35%). В зависимости от вида ангиографических находок и выбранной лечебной тактики сформированы две группы. В I группе (n = 75) у 57 пациентов гемодинамически значимых ангиографических дефектов шунтов и нативных артерий не выявлено, у 18 больных таковые дефекты отмечены, всем участникам применена консервативная терапия. Во II группу (n = 28) вошли пациенты, у которых по данным КШГ отмечены ангиографические дефекты в зоне крупных шунтированных коронарных артерий: 20 пациентам проведено эндоваскулярное лечение, 8 - повторное «открытое» хирургическое вмешательство. В III, контрольную, группу вошли 30 пациентов (0,39%) без признаков ишемического повреждения миокарда. Проанализированы данные интраоперационного флоуметрического контроля, послеоперационного электро- и эхокардиографического исследований, а также значения биохимических маркеров повреждения миокарда.  При ретроспективном анализе интраоперационных флоуметрических показателей коронарных шунтов с нарушенным кровотоком по данным КШГ скорость кровотока составила менее 20 мл/мин, а пульсовой индекс превышал 3,0.Результаты. Устойчивой связи между ишемическими изменениями, зафиксированными на ЭКГ и ЭхоКГ, и ангиографическими данными не обнаружено. При сравнительном анализе значений тропонина у пациентов I группы (группа с нарушением функции коронарных шунтов) и группы контроля (группа III) выявлены достоверные отличия во всех временных интервалах (1, 6, 12, 24 и 48 ч).Заключение. Совокупность выявленных предикторов дисфункции коронарных шунтов в раннем послеоперационном периоде аортокоронарного шунтирования позволяет определить показания к проведению неотложной КШГ.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To determine indications to emergency coronary artery bypass angiography.Methods. 7,616 medical records of patients with coronary artery disease who underwent isolated CABG in the period from 2012 to 2019 at the Federal Center for Cardiovascular Surgery were reviewed. Of them, 103 (1.35%) patients underwent emergency coronary artery bypass graft angiography in the early postoperative period to verify signs of myocardial damage. Patients were assigned to two groups based on angiographic findings and selected treatment strategy. Out of 75 patients, 57 patients from Group 1 had no severe angiographic signs of occlusive changes of the grafts and native arteries. But 18 patients reported failed graft and required conservative management. Group 2 (n = 28) included patients who had failed coronary artery bypass grafts according to angiography findings. 20 patients underwent endovascular treatment, and 8 patients underwent repeated surgery. The control group included 30 patients (0.39%) without any signs of ischemic myocardial damage. Intraoperative flow was assessed as well as postoperative electrocardiographic and echocardiographic records. Biochemical markers of myocardial damage were measured.Results. Blood flow velocity was less than 20 ml/min, and the pulsatility index exceeded 3.0 according to the intraoperative flow assessment of coronary artery bypass grafts with impaired blood flow according to angiography findings. There was no relationship found between ischemic changes according to ECG, ECHO-CG, and angiographic findings. Significant differences were found in troponin I levels between Group 1 (patients with coronary artery graft dysfunction) and the control group (Group 3) at all time intervals (1, 6, 12, 24 and 48 hours).Conclusion. The predictors of failed coronary artery bypass grafts in the early postoperative period allowed identifying indications to emergency angiography.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Острый инфаркт миокарда</kwd><kwd>Тропонин I</kwd><kwd>Флоуметрия</kwd><kwd>Коронарное шунтирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Acute myocardial infarction</kwd><kwd>Troponin I</kwd><kwd>Flow assessment</kwd><kwd>Coronary artery bypass graft</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Авторы заявляют об отсутствии финансирования исследования.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сердечно-сосудистые заболевания [электронный ресурс]. 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