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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kpccz</journal-id><journal-title-group><journal-title xml:lang="ru">Комплексные проблемы сердечно-сосудистых заболеваний</journal-title><trans-title-group xml:lang="en"><trans-title>Complex Issues of Cardiovascular Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2306-1278</issn><issn pub-type="epub">2587-9537</issn><publisher><publisher-name>Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17802/2306-1278-2021-10-3-15-25</article-id><article-id custom-type="elpub" pub-id-type="custom">kpccz-912</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ. Кардиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES. Cardiology</subject></subj-group></article-categories><title-group><article-title>Эффекты когнитивной реабилитации с применением двойной задачи у пациентов в раннем послеоперационном периоде прямой реваскуляризации миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Effects of dual-task rehabilitative training in the early postoperative period after direct myocardial revascularization</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6391-0170</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарасова Ирина Валерьевна - доктор медицинских наук ведущий научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Tarasova Irina V., Ph.D, Senior Researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><email xlink:type="simple">taraiv@kemcardio.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8260-8033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубникова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubnikova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трубникова Ольга Александровна - доктор медицинских наук заведующая лабораторией нейрососудистой патологии отдела клинической кардиологии.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Trubnikova Olga A., Ph.D, Head of the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6813-7017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кухарева</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuhareva</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кухарева Ирина Николаевна - кандидат медицинских наук, врач-невролог, научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Kuhareva Irina N., Ph.D, neurologist, researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8908-2070</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соснина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sosnina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соснина Анастасия Сергеевна - кандидат медицинских наук врач-кардиолог, научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Sosnina Anastasia S., Ph.D, cardiologist, researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9750-5536</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куприянова</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kupriyanova</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куприянова Дарья Сергеевна, лаборант-исследователь лаборатории ультразвуковых и электрофизиологических методов исследований отдела диагностики сердечно-сосудистых заболеваний.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Kupriyanova Darya S., research assistant at the Laboratory of Electrophysiological and Ultrasound study methods, Department of Cardiovascular Disease Diagnostics.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6086-9398</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестернин</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shesternin</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шестернин Виктор Гавриилович - врач по ЛФК и спортивной медицине отделения медицинской реабилитации.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Shesternin Viktor G., physical therapist, sports medicine specialist at the Department of Medical Rehabilitation.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4361-9853</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нагирняк</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nagirnyak</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нагирняк Ольга Алексеевна - кандидат медицинских наук врач-кардиолог, научный сотрудник лаборатории нейрососудистой патологии отдела клинической кардиологии.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Nagirnyak Olga A., Ph.D., cardiologist, researcher at the Laboratory of Neurovascular Pathology, Department of Clinical Cardiology.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4642-3610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Барбараш Ольга Леонидовна, член-корреспондент РАН, доктор медицинских наук, профессор директор.</p><p>Сосновый бульвар, 6, Кемерово, 650002</p></bio><bio xml:lang="en"><p>Barbarash Olga L., Ph.D., Professor, Corresponding Member of the Russian Academy of Sciences, Director.</p><p>6, Sosnoviy Blvd., Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Кузбасский клинический кардиологический диспансер имени академика Л.С. Барбараша</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Institution Kuzbass Clinical Cardiology Dispensary named after academician L.S. Barbarash</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>23</day><month>09</month><year>2021</year></pub-date><volume>10</volume><issue>3</issue><fpage>15</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тарасова И.В., Трубникова О.А., Кухарева И.Н., Соснина А.С., Куприянова Д.С., Шестернин В.Г., Нагирняк О.А., Барбараш О.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Тарасова И.В., Трубникова О.А., Кухарева И.Н., Соснина А.С., Куприянова Д.С., Шестернин В.Г., Нагирняк О.А., Барбараш О.Л.</copyright-holder><copyright-holder xml:lang="en">Tarasova I.V., Trubnikova O.A., Kuhareva I.N., Sosnina A.S., Kupriyanova D.S., Shesternin V.G., Nagirnyak O.A., Barbarash O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nii-kpssz.com/jour/article/view/912">https://www.nii-kpssz.com/jour/article/view/912</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценить влияние когнитивной реабилитации с применением двойной задачи на когнитивные, постуральные функции и показатели электроэнцефалограммы у пациентов в раннем послеоперационном периоде прямой реваскуляризации миокарда.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В проспективном рандомизированном исследовании участвовали 48 пациентов, подвергнутых коронарному шунтированию. Путем простой рандомизации (метод конвертов) сформированы группы послеоперационного когнитивного тренинга (n = 23) и сравнения (n = 25). Основной группе когнитивный тренинг проводили ежедневно, с 3-4-го дня после операции и до выписки из стационара в виде 15-20-минутных сессий с выполнением двойных заданий (постуральный тренинг и когнитивная задача). Всем больным оценены нейрофизиологический статус (психометрическое тестирование и электроэнцефалографическое исследование) и стабилография за 3-5 дней до и на 8-11-е сут после вмешательства.</p></sec><sec><title>Результаты</title><p>Результаты. В раннем послеоперационном периоде кардиохирургических вмешательств у пациентов, прошедших когнитивный тренинг, число случаев послеоперационной когнитивной дисфункции (ПОКД) составило 39%, тогда как в группе сравнения - 64%. Относительный риск развития ПОКД в группе без когнитивного тренинга - 2,77 (95% доверительный интервал 0,86-8,91; Z = 1,704; p = 0,08). В группе когнитивного тренинга наблюдалось увеличение                интегрального показателя когнитивного статуса по сравнению с предоперационным уровнем (Z = 2,58; p = 0,01) при отсутствии статистически значимых различий в группе сравнения. Также обнаружено, что мощность биопотенциалов тета-1-ритма увеличилась по сравнению с дооперационными показателями только у больных группы сравнения, тогда как у участников, прошедших программу когнитивного тренинга, не выявлено статистически значимого послеоперационного увеличения тета-активности.</p></sec><sec><title>Заключение</title><p>Заключение. Показано положительное влияние когнитивной реабилитации с применением двойной задачи на нейрофизиологические показатели пациентов, перенесших прямую реваскуляризацию миокарда, в виде меньшей частоты ПОКД, улучшения когнитивного статуса и менее выраженной корковой дисфункции, что позволяет говорить об эффективности этого когнитивного тренинга для анализируемой выборки. Необходимо дополнительно рассмотреть вопросы продолжительности и интенсивности тренинга с использованием двойных задач для повышения восстановительного эффекта на интеллектуальные ресурсы и постуральные функции больных в послеоперационном периоде прямой реваскуляризации миокарда.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To assess the effects of cognitive rehabilitation with dual-task training that involves a cognitive task combined with postural and walking control, as well as electroencephalogram indices in patients in the early postoperative period after direct myocardial revascularization.</p></sec><sec><title>Methods</title><p>Methods. The study enrolled 48 patients scheduled for coronary artery bypass graft surgery. Subjects in this prospective, randomized study were randomized using envelopes to a postoperative cognitive training group (n = 23) and non-training group (n = 25). The cognitive training was carried out daily, starting 3-4 days after the procedure and until the discharge order. Dual tasks training (a cognitive task combined with postural and walking control) lasted 15-20 minutes. All patients were submitted to an extended neurophysiological assessment (psychometric tests and electroencephalogram study) and stabilography 3-5 days before and 8-11 days after coronary artery bypass grafting.</p></sec><sec><title>Results</title><p>Results. The patients who underwent cognitive training experienced postoperative cognitive dysfunction (POCD) in 39% cases in the early postoperative period after intervention, while the non-training group - in 64%. The relative risk of developing POCD in the non-training group was 2.77 (95% CI: 0.86-8.91, Z = 1.704, p = 0.08). The patients in cognitive training exhibited better cognitive state compared to the preoperative state (Z = 2.58; p = 0.01) in the absence of statistically significant differences in the non-training group. Moreover, type-1 theta power values increased in the non-training group in comparison to the preoperative values, while the cognitive training group did not have a statistically significant difference in theta power.</p></sec><sec><title>Conclusion</title><p>Conclusion. Positive effects of dual task rehabilitation on the neurophysiological parameters of patients undergoing direct myocardial revascularization were demonstrated. Positive effects include lower frequency of POCD, improved cognitive state and less pronounced cortical dysfunction. The dual task training had proved a suitable training method for this category of patients. Additional studies are required to test the possibility of increasing the duration and intensity of dual task training for stronger recovery effect and improved cognitive and walking performance of patients in the postoperative period after direct myocardial revascularization.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивный тренинг</kwd><kwd>двойная задача</kwd><kwd>постуральные функции</kwd><kwd>стабилография</kwd><kwd>электроэнцефалограмма</kwd><kwd>ишемия мозга</kwd><kwd>коронарное шунтирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive training</kwd><kwd>dual task</kwd><kwd>postural functions</kwd><kwd>stabilography</kwd><kwd>eeg</kwd><kwd>cerebral ischemia</kwd><kwd>coronary artery bypass graft surgery</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке РФФИ и Кемеровской области, проект № 20-415-420005</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fraga F.J., Mamani G.Q., Johns E., Tavares G., Falk T.H., Phillips N.A. 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