AWARENESS, TREATMENT AND CONTROL OF ARTERIAL HYPERTENSION IN THE POPULATION (LITERATURE REVIEW)
https://doi.org/10.17802/2306-1278-2024-13-4S-168-182
Abstract
Highlights
It is important to implement programs to improve prevention, awareness, and control of arterial hypertension. The levels of hypertension control vary depending on populations and time periods. This review presents an assessment of the variation in awareness, treatment, and control of hypertension in modern populations around the world.
Abstract
High blood pressure (BP) is a major risk factor in the development of premature death and disability throughout the world. We conducted an analytical review of the medical research publications for the period 2005–2023, which assessed the prevalence, awareness, treatment and control of hypertension (HT) in various populations in the contemporary period. For literature search we used electronic databases of Google Academy (https://scholar.google.ru/), PubMed (https://pubmed.ncbi.nlm.nih.gov), eLIBRARY.ru (https://www.elibrary), and the data from international and Russian journals dedicated to cardiology and internal medicine. The results of the analysis showed significant geographical variations in the HT prevalence (from < 20% to > 60%); predominantly high rates of HT awareness and treatment in developed countries (up to > 80%) with low relevant indicators in underdeveloped countries, for example, in Sub-Saharan African regions (below 15–20%). The level of hypertension control varies from < 10% to > 60%. The assessment of adherence to the guidelines for CVD prevention, is most consistently reported by the series of EUROASPIRE I–V, NHANES, NCD Risk factor Collaboration, ESSE-RF studies. Despite the availability of modern guidelines for the management of HT and existence of effective and safe antihypertensive drugs, the control of HT is very difficult. According to generalized data, about 50% of hypertensive patients do not achieve target BP levels. Recent trends demonstrate that a dual approach to reducing HT through primary prevention and improved treatment and control is achievable not only in high-income countries, but also in middle- and low-income settings. Accordingly, the implementation of coordinated programs to improve the prevention, detection, education, treatment and control of hypertension is warranted and important worldwide.
About the Authors
Ekaterina V. MazdorovaRussian Federation
PhD, Senior Researcher at the Laboratory of Ethiopathogenesis and Clinical Presentation of Internal Diseases, Research Institute of Internal and Preventive Medicine – Branch of the Federal State Budgetary Institution “Institute of Cytology and Genetics of the Siberian Branch of Russian Academy of Sciences”, Novosibirsk, Russian Federation
Bermet A. Asketova
Russian Federation
2nd year Clinical Resident (Cardiology), Research Institute of Internal and Preventive Medicine – Branch of the Federal State Budgetary Institution “Institute of Cytology and Genetics of the Siberian Branch of Russian Academy of Sciences”, Novosibirsk, Russian Federation
Andrey N. Ryabikov
Russian Federation
PhD, Professor, Leading Researcher at the Laboratory of Ethiopathogenesis and Clinical Presentation of Internal Diseases, Research Institute of Internal and Preventive Medicine – Branch of the Federal State Budgetary Institution “Institute of Cytology and Genetics of the Siberian Branch of Russian Academy of Sciences”, Novosibirsk, Russian Federation
Sofia K. Malyutina
Russian Federation
PhD, Professor, Head of the Laboratory of Ethiopathogenesis and Clinical Presentation of Internal Diseases, Research Institute of Internal and Preventive Medicine – Branch of the Federal State Budgetary Institution “Institute of Cytology and Genetics of the Siberian Branch of Russian Academy of Sciences”, Novosibirsk, Russian Federation
References
1. WHO. A global brief on hypertension: Silent killer, global public health crisis: World Health. Available at: http://www.who.int/cardiovascular_diseases/publications/global_brief_hypertension/en/ (accessed 23.06.2024)
2. Williams B., Mancia G., Spiering W., Agabiti Rosei E., Azizi M., Burnier M., Clement D.L., Coca A., de Simone G., Dominiczak A., et al. 2018 ESC/ESH Guidelines for the managem.t of arterial hypertension. The Task Force for the managem.t of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). J Hypertens. 2018;36(10):1953-2041. doi: 10.1097/HJH.0000000000001940.
3. Chazova I.E., Zhernakova Yu.V. on behalf of the experts. Clinical guidelines. Diagnosis and treatm.t of arterial hypertension. Systemic Hypertension.2019;16 (1):6–31.doi:10.26442/2075082X.2019.1.190179 (In Russian)
4. WHO. Regional Office for Europe. (2005). European health for all database (HFA-DB). Available at: https://apps.who.int/iris/handle/10665/108565 (accessed 24.02.2024]
5. Kearney P.M., Whelton M., Reynolds K., Muntner P., Whelton P.K., He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005; 365(9455): 217–223. doi: 10.1016/S0140-6736(05)17741-1
6. Lewington S., Clarke R., Qizilbash N., Peto R., Collins R.; Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002; 360(9349):1903–1913. doi: 10.1016/S0140-6736(02)11911-8
7. Vishram J.K., Borglykke A., Andreasen A.H., Jeppesen J., Ibsen H., Jorgensen T., Broda G., Palmieri L., Giampaoli S., Donfrancesco C., Kee F., Mancia G., Cesana G., Kuulasmaa K., Sans S., Olsen M.H.; MORGAM Project. Impact of age on the importance of systolic and diastolic blood pressures for stroke risk: the MOnica, Risk,Genetics, Archiving, and Monograph (MORGAM) project. Hypertension. 2012;60(5):1117–1123. doi: 10.1161/HYPERTENSIONAHA.112.201400
8. Brown D.W., Giles W.H., Greenlund K.J. Blood pressure parameters and risk of fatal stroke, NHANES II mortality study. Am J Hypertens. 2007; 20(3):338–341. doi: 10.1016/j.amjhyper.2006.08.004.
9. Whelton P.K., Carey R.M., Aronow W.S., Casey D.E.Jr., Collins K.J., Himmelfarb C.D., DePalma S.M., Gidding S., Jamerson K.A., Jones D.W., et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Managem.t of High Blood Pressure in Adults. A Report of the American College of Cardiology. American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018;71(19):e127-248. doi: 10.1016/j.jacc.2017.11.006.
10. Mancia G., Kreutz R., Brunstr€omc M., Burnierd M., Grassie G., Januszewiczf A., Muiesan M.L., Tsioufis K., Agabiti-Rosei E., Algharably E.A.E., et al. 2023 ESH Guidelines for the managem.t of arterial hypertension. The Task Force for the managem.t of arterial hypertension of the European Society of Hypertension Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). J of Hypertesion, 2023; 41(12): 1874-2071. Doi: 10.1097/01.hjh.0000431740.32696.cc
11. Kotseva K., De Backer G., De Bacquer D., Rydén L., Hoes A., Grobbee D., Maggioni A., Marques-Vidal P., Jennings C., Abreu A., et al.; EUROASPIRE Investigators. Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry. Eur J Prev Cardiol. 2019;26(8):824-835. doi: 10.1177/2047487318825350.
12. Zhang Y., Moran A.E. Trends in the Prevalence, Awareness, Treatm.t, and Control of Hypertension among Young Adults in the United States, 1999–2014. Hypertension. 2017;70(4):736–742. doi:10.1161/HYPERTENSIONAHA.117.09801.
13. Joffres M., Falaschetti E., Gillespie C., Robitaille C., Loustalot F., Poulter N., McAlister F.A., Johansen H., Baclic O., Campbell N. Hypertension prevalence, awareness, treatm.t and control in national surveys from England, the USA and Canada, and correlation with stroke and ischemic heart disease mortality: a cross-sectional study. BMJ Open. 2013; 3(8): e003423. doi: 10.1136/bmjopen-2013-003423
14. NCD Risk Factor Collaboration. Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurem.t studies with 19.1 million participants. Lancet 2017; 389(10064):37–55. doi: 10.1016/S0140-6736(16)31919-5.
15. NCD Risk Factor Collaboration (NCD-RisC) Long-term and recent trends in hypertension awareness, treatm.t, and control in 12 high-income countries:an analysis of 123 nationally representative surveys. Lancet. 2019; 394: 639–51. doi:10.1016/ S0140-6736(19)31145-6.
16. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatm.t and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. The Lancet. 2021; 398: 957-980. doi: 10.1016/S0140-6736(21)01330-1.
17. Muromtseva G.A., Kontsevaya A.V., Konstantinov V.V., Artamonova G.V., Gatagonova T.M., Duplyakov D.V., Efanov A.Yu., Zhernakova Yu.V., Il’in V.A., Konradi A.O., et al. The prevalence of non-infectious diseases risk factors in Russian population in 2012-2013 years. The results of ECVD-RF. Cardiovascular Therapy and Prevention. 2014; 13(6): 4–11 doi:10.15829/1728-8800-2014-6-4-11 (In Russian)
18. Boytsov S.A., Balanova Yu.A., Shalnova S.A., Deev A.D., Artamonova G.V., Gatagonova T.M., Duplyakov D.V., Efanov A.Yu., Zhernakova Yu.V., Konradi A.O., et al. Arterial hypertension among individuals of 25–64 y.o.: prevalence, awareness, treatment and control. By the data from ESSE. Cardiovascular Therapy and Prevention. 2014;13(4):4-14. doi:10.15829/1728-8800-2014-4-4-14 (In Russian)
19. Ismarova G.S. Prevalence of arterial hypertension: awareness and admission to hypotensive therapy taking into account the age characteristics of residents in urban and rural areas. Science, new technologies and innovations of Kyrgyzstan. 2022;9:121-124. doi: 10.26104/NNTIK.2023.33.23.022 (In Russian)
20. Mills K.T., Bundy J.D., Kelly T.N., Reed J.E., Kearney P.M., Reynolds K., Chen J., He J. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016; 134:441–450. doi: 10.1161/CIRCULATIONAHA.115.018912
21. Basu S., Millett Chr. Social Epidemiology of Hypertension in Middle-Income Countries Determinants of Prevalence, Diagnosis, Treatment, and Control in the WHO SAGE Study. Hypertension. 2013;62:18-26. doi: 10.1161/HYPERTENSIONAHA.113.01374.
22. Hopstock L.A., Eggen A.E., Løchen M.L., Mathiesen E.B., Nilsen A., Njølstad I., Wilsgaard T. Blood pressure target achievement and antihypertensive medication use in wom. and m. after first-ever myocardial infarction: the Tromsø Study 1994-2016. Open Heart. 2018;5(1):e000746. doi: 10.1136/openhrt-2017-000746.
23. Ostchega Y., Fryar C.D., Nwankwo T., Nguyen D.T. Hypertension Prevalence Among Adults Aged 18 and Over: United States, 2017-2018. NCHS Data Brief. 2020;(364):1-8.
24. Lewington S., Lacey B., Clarke R., Guo Y., Kong X.L., Yang L., Chen Y., Bian Z., Chen J., Meng J., Xiong Y., He T., Pang Z., Zhang S., Collins R., Peto R., Li L., Chen Z.; China Kadoorie Biobank Consortium. The Burden of Hypertension and Associated Risk for Cardiovascular Mortality in China. JAMA Intern Med. 2016;176(4):524-32. doi:10.1001/jamainternmed.2016.0190.
25. Balanova Y.A., Shalnova S.A., Imaeva A.E., Kapustina A.V., Muromtseva G.A., Evstifeeva S.E. et al. on behalf of ESSE-RF-2 researchers. Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSE-RF-2 Study). Rational Pharmacotherapy in Cardiology 2019;15(4):450-466. doi:10.20996/1819-6446-2019-15-4-450-466 (In Russian)
26. Balanova Yu.A., Shalnova S.A., Deyev A.D., Konstantinov V.V., Kapustina A.V. Dynamics of arterial hypertension and its impact on mortality in the Russian population. 2014. Systemic hypertension. 2014; 11(4): 17-21. (In Russian)
27. Petersen J., Kontsevaya A., McKee M., Kudryavtsev A.V., Malyutina S.K., Cook S., Leon D.A. Untreated hypertension in Russian 35-69 year olds – a cross-sectional study. PLoS One. 2020; 15(5):e0233801. doi:10.1371/journal.pone.0233801
28. Lu W., Pikhart H., Tamosiunas A., Kubinova R., Capkova N., Malyutina S., Pająk A., Bobak M. Prevalence, awareness, treatm.t and control of hypertension, diabetes and hypercholesterolemia, and associated risk factors in the Czech Republic, Russia, Poland and Lithuania: a cross‑sectional study. BMC Public Health 2022; 22:883. doi:10.1186/s12889-022-13260-3
29. Malyutina S.K., Mazdorova E.V., Shapkina M.Y., Avdeeva E.M., Maslacov N.A., Simonova G.I., Bobak M., Nikitin Yu.P., Ryabikov A.N. The profile of drug treatment in subjects aged over 50 years with hypertension in an urban Russian population. Kardiologiia. 2020;60(3):21-29. doi:10.18087/cardio.2020.3.n948 (In Russian)
30. Unger T., Borghi C., Charchar F., Khan N.A., Poulter N.R., Prabhakaran D., Ramirez A., Schlaich M., Stergiou G.S., Tomaszewski M., Wainford R.D., Williams B., Schutte A.E. 2020 International Society of Hypertension global hypertension practice guidelines. J Hypertens. 2020;38(6):982-1004. doi: 10.1097/HJH.0000000000002453.
31. Kobalava Zh.D., Konradi A.O., Nedogoda S.V., Shlyakhto E.V., Arutyunov G.P., Baranova E.I., Barbarash O. L., Boitsov S.A., Vavilova T.V., Villevalde S.V., et al. Arterial hypertension in adults. Clinical guidelines 2020. Russian Journal of Cardiology. 2020;25(3):3786. doi:10.15829/1560-4071-2020-3-3786 (In Russian)
32. Shalnova S.A.,Konradi A.О.,Balanova Yu.A.,Deev A.D.,Imaeva A.E.,Muromtseva G.A., Evstifeeva S.E., Kapustina A.V., Shlyakhto E.V., Boytsov S.A., Drapkina О.М. What factors do influence arterial hypertension control in Russia. Cardiovascular Therapy and Prevention. 2018;17(4):53-60. doi:10.15829/1728-8800-2018-4-53-60 (In Russian)
33. Shalnova S.A., Deev A.D., Balanova Yu.A., Kapustina A.V., Imaeva A.E., Muromtseva G.A., Kiseleva N.V., Boytsov S.A. Twenty years trends of obesity and arterial hypertension and their association in Russia. Cardiovascular Therapy and Prevention, 2017; 16(4): 4–10. doi:10.15829/1728-8800-2017-4-4-10 (In Russian)
34. Chung S.-C., Pujades-Rodriguez M., Duyx B., Denaxas S.C., Pasea L., Hingorani A., Timmis A., Williams B., Hemingway H. Time spent at blood pressure target and the risk of death and cardiovascular diseases. PLoS ONE. 2018;13(9):e0202359. doi: 10.1371/journal.pone.0202359.
35. Egan B.M., Zhao Y., Axon R.N., Brzezinski W.A., Ferdinand K.C. Uncontrolled and apparent treatm.t resistant hypertension in the united states, 1988 to 2008. Circulation. 2011;124(9):1046–1058. doi: 10.1161/CIRCULATIONAHA.111.030189.
36. Kim T.-H., Yang P.-S., Yu H.T., Jang E., Shin H., Kim H.Y., Uhm J.S., Kim J.Y., Sung J.H., Pak H.N., Lee M.H., Joung B., Lip G.Y.H. Effect of hypertension duration and blood pressure level on ischaemic stroke risk in atrial fibrillation: nationwide data covering the entire Korean population. Eur Heart J. 2019 ;40(10);809-819. doi: 10.1093/eurheartj/ehy877.
37. World Health Organization. MONICA monograph and multimedia sourcebook: world's largest study of heart disease, stroke, risk factors, and population trends 1979-2002. edited by Tunstall-Pedoe H. Available at: https://apps.who.int/iris/handle/10665/42597 (accessed 24.02.2024]
38. Monitoring of cardiovascular morbidity, mortality and risk factors in different regions of the world (WHO MONICA project). In two volumes. Eds. Nikitin Yu. P. Novosibirsk: Academic Publishing House Geo Limited, 2016. P. 293-313. (In Russian)
39. Wolf H.K., Tuomilehto J., Kuulasmaa K. Domarkiene S., Cepaitis Z., Molarius A., Sans S., Dobson A., Keil U., Rywik S. Blood pressure levels in the 41 populations of the WHO MONICA Project. J Hum Hypertens. 1997; 11(11):733-42. doi: 10.1038/sj.jhh.1000531.]
40. Kuulasmaa K., Tunstall-Pedoe H., Dobson A., Fortmann S., Sans S., Tolonen H., Evans A., Ferrario M., Tuomilehto J. Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet. 2000; 355(9205):675-87. doi: 10.1016/s0140-6736(99)11180-2.
41. Malyutina S., Simonova G., Nikitin Yu. The incidence of coronary heart disease and cardiovascular mortality in the urban Siberian population: Gender specific findings from the 10-year cohort study. In: Heart Disease: Environmet, Stress and Gender. Eds. Weidner G., Kopps M., Kristenson M. msterdam, The Netherlands: IOS Press – NATO Science Series. Series I: Life and Behavioral Sciences. 2002; 327: 69-79.
42. Kontstantinov V.V., Zhukovsky G.S., Oganov R.G., Burlutsky G.I., Deev A.D., Barsov D.A., Smirnova I.P., Shestov D.B., Volozh O.I., Serova N.V., et al. Epidemiology of systolic and diastolic arterial hypertension in connection with risk factors and education among m. population in some cities of Russia, CIS countries and Baltic states (a cooperative study). Therapeutic archive. 1994; 1: 54-47. (In Russian)
43. Zhukovsky G.S., Kontstantinov V.V., Varlamova T.A., Kapustina A.V. Arterial hypertension: epidemiological situation in Russia and other countries. Russian Medical Journal. 1997; 5: 551-558. (In Russian)
44. Shalnova S.A., Balanova Yu.A., Konstantinov V.V., Timofeeva T.N., Ivanov V.M., Kapustina A.V., Deev A.D. Arterial hypertension: prevalence, awareness, antihypertensive pharmaceutical treatment, treatmment effectiveness in Russian population. Russian Journal of Cardiology. 2006;(4):45-50. (In Russian)
45. Chazova I.E., Oschepkova E.V. Results of the Federal (National) Project for Prevention and Treatm.t Essential Hypertension Patients in Russia from 2002–2012 Years. Bulletin of the Russian Academy of Medical Sciences. 2013, 68(2):4-11. doi:10.15690/vramn.v68i2.542 (In Russian)
46. Pogosova N.V., Oganov R.G., Boytsov S.A., Ausheva A.K., Sokolova O.Yu., Kursakov A.A., Osipova I.V., Antropova O.N., Pozdnyakov Yu.M., Salbieva A.O., et al .Secondary prevention in patients with coronary artery disease in Russia and Europe: results from the Russian part of the EUROASPIRE V survey. Cardiovascular Therapy and Prevention.2020;19(6):2739. doi:10.15829/1728-8800-2020-2739 (In Russian)
47. Cook S., Hopstock L.A., Eggen A.E., Bates K., Iakunchykova O., Kontsevaya A., McKee M, Schirmer H, Voevoda M, Kudryavtsev AV, Malyutina S, Leon DA. Pharmacological managem.t of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: comparison between population-based studies in Russia and Norway. BMC Cardiovascular Disorders. 2020;20(1):234. doi:10.1186/s12872-020-01513-1
48. Petersen J., Malyutina S.K., Ryabikov A.N., Kontsevaya A., Kudryavtsev A.V., Eggen A.E., McKee M., Cook S., Hopstock L.A., Schirmer H., Leon D.A. Uncontrolled and apparent treatm.t resistant hypertension: a cross-sectional study of Russian and Norwegian 40-69 year olds. BMC Cardiovasc Disord. 2020(b); 20(1):135.doi:10.1186/s12872-020-01407-2
49. Drapkina O.M., Shalnova S.A., Imaeva A.E., Balanova Yu.A., Maksimov S.A., Muromtseva G.A., Kutsenko V.A., Karamnova N.S., Evstifeeva S.E., Kapustina A.V., et al. Epidemiology of Cardiovascular Diseases in Regions of Russian Federation. Third survey (ESSE-RF-3). Rationale and study design. Cardiovascular Therapy and Prevention. 2022;21(5):3246. doi:10.15829/1728-8800-2022-3246 (In Russian)
Supplementary files
Review
For citations:
Mazdorova E.V., Asketova B.A., Ryabikov A.N., Malyutina S.K. AWARENESS, TREATMENT AND CONTROL OF ARTERIAL HYPERTENSION IN THE POPULATION (LITERATURE REVIEW). Complex Issues of Cardiovascular Diseases. 2024;13(4S):168-182. (In Russ.) https://doi.org/10.17802/2306-1278-2024-13-4S-168-182