OUTCOMES OF COMPLEX RECONSTRUCTION OF THE TRICUSPID VALVE: FROM THE RING TO THE LEAFLETS AND SUBVALVULAR STRUCTURES
https://doi.org/10.17802/2306-1278-2025-14-3-140-151
Abstract
Highlights
This paper presents the long-term results of complex tricuspid valve reconstructions in severe secondary tricuspid insufficiency, such as the extension of the anterior tricuspid valve flap, the “clover” technique, as well as the immediate results of the convergence of the papillary muscles of the right ventricle. This generalized material has no analogues in the Russian-language literature and familiarization with it will expand the indications, durability and safety of tricuspid valve reconstructions.
Abstract
Aim. Tricuspid annuloplasty of the tricuspid valve is the most common and, in the vast majority of cases, the only intervention on the tricuspid valve performed for tricuspid regurgitation. However, there are a number of problems that cause dissatisfaction with a single-component treatment of the tricuspid valve, such as: the risk of recurrence of TR 2, varying from 10 to 32% depending on the annuloplasty method; high mortality during reoperation on the tricuspid valve due to the return of TR.
Methods. From 2010 to 2017, anterior leaflet augmentation of the tricuspid valve was performed in 18 patients with severe TR. According to the etiology of TR, the patients were divided into 2 groups: Group 1 – patients with organic disease of the tricuspid valve (rheumatism – 10 patients, congenital heart disease – 2 patients); Group 2 – with functional TR (6 patients). For the period from 2004 to 2019. The “clover” technique was used in TR correction in 28 patients. Myxomatosis was the predominant etiology of TR in 16 cases, functional disease of the tricuspid valve – 7 patients, rheumatism – 3 patients, infective endocarditis – 2 patients.
Results. Freedom from recurrence of TR ≥ grade 2 in the long-term period in the “clover” group was 75% (with myxomatosis – 85,7%), in the “augmentation” group – 100% with functional defect and 60% with organic valve disease. Freedom from recurrence of TR ≥ grade 3 in the “edge to edge” group was 87.5% (with myxomatosis – 100%), in the “augmentation” group – 100% with functional disease and 81.8% with organic valve disease. In the edge-to-edge group, a correlation was found between the degree of TR in the late period and the implementation of additional maneuvers on the tricuspid valve (excision of secondary chords and anterior leaflet augmentation r = 0.5, p = 0.037 and r = 0.5, p = 0.048, respectively).
Conclusion. The results of anterior leaflet augmentation of the tricuspid valve in case of functional TR, the edge-to-edge suture in case of valve myxomatosis are satisfactory and allow to expand the indications for reconstructive surgery, the techniques are reproducible, safe and durability.
About the Authors
Bagrat V. KazumyanRussian Federation
PhD, Cardiovascular Surgeon, A.N. Bakulev National Medical Research Center for Cardiovascular Surgery of the Russian Ministry of Health, Moscow, Russian Federation
Dmitriy A. Titov
Russian Federation
PhD, Cardiovascular Surgeon, A.N. Bakulev National Medical Research Center for Cardiovascular Surgery of the Russian Ministry of Health, Moscow, Russian Federation
Svetlana I. Babenko
Russian Federation
PhD, cardiologist, A.N. Bakulev National Medical Research Center for Cardiovascular Surgery of the Russian Ministry of Health, Moscow, Russian Federation
References
1. Ulas Höke, Dominique Auger, Joep Thijssen, Ron Wolterbeek , Enno T van der Velde, Eduard R Holman et al. Heart. 2014; 100 (12): 960-8. DOI: 10.1136/heartjnl-2013-304673.
2. Rodes-Cabau J, Taramasso M, O’Gara PT. Diagnosis and treatment of tricuspid valve disease: current and future perspectives. Lancet. 2016; 388:2431-2442. DOI: 10.1016/S0140-6736(16)00740-6
3. Nelson Wang, Jordan Fulcher, Nishan Abeysuriya, Michele McGrady, Ian Wilcox, David Celermajer, Sean Lal. Тricuspid regurgitation is associated with increased mortality independent of pulmonary pressures and right heart failure: a systematic review and meta-analysis. European Heart Journal. 2019; 40 (5): 476–484. DOI: 10.1093/eurheartj/ehy641.
4. Navia JL, Nowicki ER, Blackstone EH, Brozzi NA, Nento DE, Atik FA et al. Surgical management of secondary tricuspid valve regurgitation: annulus, commissure, or leaflet procedure? J Thorac Cardiovasc Surg 2010; 139:1 473–82. DOI: 10.1016/j.jtcvs.2010.02.046
5. Kazumyan B.V., Muratov R.M., Soboleva N.N. Outcomes of ring versus suture annuloplasty of the tricuspid valve in patients with functional tricuspid valve disease. Grudnaya i Serdechno-Sosudistaya Khirurgiya (Russian Journal of Thoracic and Cardiovascular Surgery). 2020; 4 (62): 310-317. DOI: 10.24022/0236-2791-2020-62-4-310-317.
6. Jeganathan R, Armstrong S, Al-Alao B, David T. The risk and outcomes of reoperative tricuspid valve surgery. Ann Thorac Surg 2013; 95:119–24. DOI: 10.1016/j.athoracsur.2012.08.058
7. Kilic A, Saha-Chaudhuri P, Rankin JS, et al. Trends and outcomes of tricuspid valve surgery in North America: an analysis of more than 50,000 patients from The Society of Thoracic Surgeons database. Ann Thorac Surg. 2013; 96: 1546- 1552. DOI: 10.1016/j.athoracsur.2013.06.031
8. Fukuda S, Song JM, Gillinov AM, McCarthy PM, Daimon M, Kongsaerepong V et al. Tricuspid valve tethering predicts residual tricuspid regurgitation after tricuspid annuloplasty. Circulation 2005; 111: 975–9. DOI: 10.1161/01.CIR.0000156449.49998.51
9. Muratov R.M., Kazumyan B.V., Akbutaeva G.M. Anterior leaflet augmentation with organic and functional tricuspid regurgitation. Grudnaya i Serdechno-Sosudistaya Khirurgiya, 2019; 61 (5): 429-435. DOI: https://doi.org/10.24022/0236-2791-2019-61-5-429-435.
10. Kazumyan B.V., Muratov R.M., Soboleva N.N, Titov D.A. Outcomes of ring versus suture annuloplasty of the tricuspid valve in patients with functional tricuspid valve disease. Grudnaya i Serdechno-Sosudistaya Khirurgiya (Russian Journal of Thoracic and Cardiovascular Surgery). 2022; 5 (64): 495-502. DOI: 10.24022/0236-2791-2022-64-5-495-502
11. Kazumyan B.V., Muratov R.M., Babenko S.I., Titov D.A. Risk factors and causes of late recurrence of tricuspid regurgitation after suture and band annuloplasty. Russian Journal of Thoracic and Cardiovascular Surgery. 2023; 4 (65): 391-401. DOI: 10.24022/0236-2791-2023-65-4-391-401
12. Long-term results of tricuspid valve reconstruction pericardium and neochords due to infective endocarditis in candidates for valve replacement. Muratov R.M., Amiragov R.I., Babenko S.I. Russian Journal of Thoracic and Cardiovascular Surgery. 2023; 1 (65): 34-42. DOI: 10.24022/0236-2791-2023-65-1-34-42.
13. Min S-Y, Song J-M, Kim J-H, Jang M-K, Kim Y-J, Song H et al. Geometric changes after tricuspid annuloplasty and predictors of residual tricuspid regurgitation: a real-time three-dimensional echocardiography study. Eur Heart J 2010;31:2871–80. DOI: 10.1093/eurheartj/ehq227
14. Kabasawa M, Kohno H, Ishizaka T, Ishida K, Funabashi N, Kataoka A et al. Assessment of functional tricuspid regurgitation using 320-detectorrow multislice computed tomography: risk factor analysis for re- current regurgitation after tricuspid annuloplasty. J Thorac Cardiovasc Surg 2014;147:312–20. DOI: 10.1016/j.jtcvs.2012.11.017
15. Alfieri O, De Bonis M, Lapenna E, Agricola E, Quarti A, Maisano F. The clover technique as a novel approach for correction of posttraumatic tricuspid regurgitation. J Thorac Cardiovasc Surg 2003; 126:75–9. DOI: 10.1016/s0022-5223(03)00204-6
16. Long-term results (up to 14 years) of the clover technique for the treatment of complex tricuspid valve regurgitation. Michele De Bonis, Elisabetta Lapenna, Stefania Di Sanzo, Benedetto Del Forno, Federico Pappalardo, Alessandro Castiglioni, Luca Vicentini, Alberto Pozzoli, Ilaria Giambuzzi, Azeem Latib, Davide Schiavi, Giovanni La Canna and Ottavio Alfieri. European Journal of Cardio-Thoracic Surgery 52 (2017) 125–130. DOI:10.1093/ejcts/ezx027.
17. Gilles D. Dreyfus, Shahzad G. Raja and KokMeng John Chan. Tricuspid leaflet augmentation to address severe tethering in functional tricuspid regurgitation. Eur J Cardiothorac Surg 2008; 34: 908-910. DOI: 10.1016/j.ejcts.2008.07.006.
18. Hao Tang, Zhiyun Xu, Liangjian Zou, Lin Han, Fanglin Lu, Xilong Lang and Zhigang Song. Valve Repair with Autologous Pericardium for Organic Lesions in Rheumatic Tricuspid Valve Disease. Ann Thorac Surg 2009; 87:726-730 DOI: 10.1016/j.athoracsur.2008.12.005. DOI: 10.1016/j.athoracsur.2008.12.005
19. Giuseppe Rescigno , Sandeep Hothi , Christopher Bond , Mauin Uddin , Veena Bhatti , John Stephen Billing. CorMatrix Anterior Leaflet Augmentation of the Tricuspid Valve: Midterm Results. Heart Surg Forum, 2021. 8; 24 (2): E261-E266. DOI: 10.1532/hsf.3599
20. Kentaro Honda , Hideki Kunimoto , Takahiro Fujimoto , Yoshiharu Nishimura. Four-year outcome of the tricuspid valve leaflet augmentation and ring annuloplasty in dextrocardia. Indian J Thorac Cardiovasc Surg, 2023 May;39(3):296-299. DOI: 10.1007/s12055-023-01477-9
21. Haruo Yamauchi, Nikolay V. Vasilyev, Gerald R. Marx, Hugo Loyola, Muralidhar Padala, Ajit P. Yoganathan, and Pedro J. del Nido. Right ventricular papillary muscle approximation as a novel technique of valve repair for functional tricuspid regurgitation in an ex vivo porcine model. J Thorac Cardiovasc Surg 2012; 144: 235-42. DOI: oi: 10.1016/j.jtcvs.2012.01.028.
22. Nawwar Al-Attar and Ulrik Hvass. Right papillary muscle sling: proof of concept and pilot clinical experience. European Journal of Cardio-Thoracic Surgery 43 (2013) e187–e189. DOI:10.1093/ejcts/ezt100
23. Shamsher Singh Lohchab, Ashok Kumar Chahal and Nilesh Agrawal. Papillary muscle approximation to septum for functional tricuspid regurgitation. Asian Cardiovascular & Thoracic Annals 2015, Vol. 23(6) 747–750. DOI: 10.1177/0218492315570644
24. Goro Matsumiya, Hiroki Kohno, Kaoru Matsuura, Tomoki Sakata, Yusaku Tamura, Michiko Watanabe and Hideki Ueda. Right ventricular papillary muscle approximation for functional tricuspid regurgitation associated with severe leaflet tethering. Interactive CardioVascular and Thoracic Surgery 26 (2018) 700–702. DOI:10.1093/icvts/ivx406
25. Kiyoyuki Eishi, MD, Takashi Miura, MD, Ichiro Matsumaru, MD, Kazuyoshi Tanigawa, MD, and Kikuko Obase. Spiral suspension, a novel repair technique for severe functional tricuspid regurgitation. J Thorac Cardiovasc Surg 2018; 156 (2): 649-652. DOI: 10.1016/j.jtcvs.2018.01.082.
Supplementary files
Review
For citations:
Kazumyan B.V., Titov D.A., Babenko S.I. OUTCOMES OF COMPLEX RECONSTRUCTION OF THE TRICUSPID VALVE: FROM THE RING TO THE LEAFLETS AND SUBVALVULAR STRUCTURES. Complex Issues of Cardiovascular Diseases. 2025;14(3):140-151. (In Russ.) https://doi.org/10.17802/2306-1278-2025-14-3-140-151