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INORGANIC COATINGS FOR IMPLANTS IN CARDIOVASCULAR SURGERY: CURRENT STATE OF THE ART (A REVIEW ARTICLE)

https://doi.org/10.17802/2306-1278-2025-14-3-192-202

Abstract

Highlights

  • Cardiovascular diseases remain the leading cause of mortality worldwide, driving demand for effective implantable devices (stents, valves, vascular prostheses).
  • Inorganic coatings play a pivotal role in enhancing implant biocompatibility, antithrombogenic properties, and long-term durability.
  • This literature review critically examines both advantages and limitations of inorganic coatings for cardiovascular implants.

 

Abstract

Cardiovascular implants such as stents, valves, and vascular prostheses require continuous improvement to enhance their durability and biocompatibility. This review examines contemporary inorganic coatings, including titanium nitride, metal oxides, and diamond-like carbon coatings, which demonstrate potential for improving implant hemocompatibility. Particular focus is given to their role in preventing thrombosis, restenosis, and calcification. The paper analyzes both experimental and clinical data supporting the efficacy of these coatings.

About the Authors

Andrey V. Protopopov
Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation
Russian Federation

Postgraduate Student, Junior Researcher, Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation



Maxim O. Zhulkov
Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation
Russian Federation

MD, PhD, Researcher, Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation



Dmitry A. Sirota
Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation; Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian Federation
Russian Federation

MD, PhD, Head of the Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Institute of Circulation Pathology, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation; Associate Professor, Department of Cardiovascular Surgery, Faculty of Advanced Training and Professional Retraining, Federal State Budgetary Educational Institution of Higher Education “Novosibirsk State Medical University” Ministry of Health of the Russian Federation Russian Federation, Novosibirsk, Russian Federation



Yaroslav M. Smirnov
Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation; Federal State Autonomous Educational Institution of Higher Education “Novosibirsk National Research State University”
Russian Federation

Anesthesia Nurse, Department of Anesthesiology and Intensive Care for Adult Patients, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation; Medical Student, Faculty of Medicine, V. Zelman Institute of Medicine and Psychology, Federal State Autonomous Educational Institution of Higher Education “Novosibirsk National Research State University”, Novosibirsk, Russian Federation



Alexander S. Grenadyorov
Federal State Budgetary Institution of Science “Institute of High Current Electronics” of the Siberian Branch of the Russian Academy of Sciences
Russian Federation

PhD, Senior Researcher, Laboratory of Applied Electronics, Deputy Director for Research, Federal State Budgetary Institution of Science “Institute of High Current Electronics” of the Siberian Branch of the Russian Academy of Sciences, Tomsk, Russian Federation



Maria A. Surovtseva
Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation
Russian Federation

MD, PhD, Laboratory Assistant, Laboratory of Experimental Surgery and Morphology, Institute of Experimental Biology and Medicine, Federal State Budgetary Institution “Meshalkin National Medical Research Center” of the Ministry of Health of Russian Federation, Novosibirsk, Russian Federation



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For citations:


Protopopov A.V., Zhulkov M.O., Sirota D.A., Smirnov Ya.M., Grenadyorov A.S., Surovtseva M.A. INORGANIC COATINGS FOR IMPLANTS IN CARDIOVASCULAR SURGERY: CURRENT STATE OF THE ART (A REVIEW ARTICLE). Complex Issues of Cardiovascular Diseases. 2025;14(3):192-202. (In Russ.) https://doi.org/10.17802/2306-1278-2025-14-3-192-202

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