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FACTORS ASSOCIATED WITH A PATHOLOGIC ANKLE-BRACHIAL INDEX IN PATIENTS WITH STROKE: GENDER DIFFERENCES

https://doi.org/10.17802/2306-1278-2016-2-66-74

Abstract

Today remains a topical issue of studying risk factors for stroke. One such factor is the level of pathological ankle-brachial index and gender sensitive.

Purpose. The purpose of the study. To examine gender-specific factors associated with a pathologic ankle-brachial index (ABI) in patients with acute violation of cerebral circulation (cerebral vascular accident).

Materials and methods. The patients were evaluated with the presence of cardiovascular disease, previous cardiovascular events, type, and subtype of stroke, neurological status. To assess the presence of atherosclerosis performed color duplex scanning of brachycephalic arteries and laboratory studies (lipid profile).

Results. In the present study, no significant differences in the value of ABI in men and women with acute ischemic stroke (37.0 and 42.3 % respectively, p=0, 29). However, there are gender differences in factors associated with the presence of a pathological ABI. Independent factors associated with abnormal ABI in men, are the increased levels of LDL cholesterol (p=0.02), KIM thickening (p=0.04), presence of bilateral stenosis GCA (p=0.0002) and extent of stenosis of the carotid arteries (p=0.03); in women – only the presence of bilateral stenosis GCA (p=0.03).

Conclusions. Evaluation of LPI is appropriate in patients with stroke, regardless of gender to identify the groups with increased risk of subsequent cardiovascular events and for targeted preventive actions.

About the Authors

A. N. Sumin
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation


I. N. Kukhareva
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation

Address: 6, Sosnoviy blvd., Kemerovo, 650002, Russian Federation Tel. +7 (3842) 64-33-78



Yu. A. Kolmykova
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation


M. V. Ott
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation


N. I. Vodopyanova
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation


O. A. Trubnikova
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation


A. V. Kovalenko
Federal State Budgetary Institution Research Institute or Complex Issues of Cardiovascular Diseases. Kemerovo, Russia
Russian Federation


V. Yu. Pavlova
Kemerovo State Medical Academy of Roszdrav. Kemerovo, Russia
Russian Federation


B. M. Doronin
Novosibirsk State Medical University Ministry of Health of Russia. Novosibirsk, Russia
Russian Federation


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Review

For citations:


Sumin A.N., Kukhareva I.N., Kolmykova Yu.A., Ott M.V., Vodopyanova N.I., Trubnikova O.A., Kovalenko A.V., Pavlova V.Yu., Doronin B.M. FACTORS ASSOCIATED WITH A PATHOLOGIC ANKLE-BRACHIAL INDEX IN PATIENTS WITH STROKE: GENDER DIFFERENCES. Complex Issues of Cardiovascular Diseases. 2016;(2):66-74. (In Russ.) https://doi.org/10.17802/2306-1278-2016-2-66-74

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ISSN 2306-1278 (Print)
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