NEUROCOGNITIVE DISORDERS AMONG PATIENTS WITH VISCERAL OBESITY IN PERIOPERATIVE PERIOD OF CORONARY BYPASS SURGERY
https://doi.org/10.17802/2306-1278-2016-3-59-65
Abstract
Visceral obesity (VO) is a predictor of complications after coronary artery bypass grafting (CABG), and a risk factor for cognitive and psychological disorders.
Purpose. Of our study was to investigate features of neurocognitive disorders and their interactions in patients with VO in a perioperative period of CABG.
Materials and methods. 90 patients with a body mass index from 25 to 35 kg/m2 were included in the study, they had indications for CABG. VO was assessed in terms of «waist circumference/hip circumference» (WC/HC). Group 1 included patients with VO (WC/HC >0.9 for men and WC/HC >0.85 for women), Group 2 – patients without VO (WC/HC ≤0,9 for men and WC/HC ≤0,85 for women). Cognitive functions were evaluated with the use of the automated complex software Status PF (Kemerovo,Russia). The Spielberger State-Trait Anxiety Inventory (STAI-T, STAI-S) was used for an estimation of anxiety.
Results. Group 1 showed statistically lower rates of attention and neurodynamics and higher levels of depression and anxiety in the perioperative period of CABG. Group 1 demonstrated the decrease in memory and neurodynamics scores as STAI-T levels were higher in the perioperative period of CABG; the growth of STAI-T levels in Group 2 did not always lead to the derangements of attention and neurodynamics scores. Moreover, in Group 2 higher attention and neurodynamics scores were at higher STAI-T levels in 6 months after CABG. High STAI-S levels in both groups negatively affected the performance of attention and neurodynamics in the perioperative period of CABG.
Conclusion. Patients with VO have a higher risk of developing neurocognitive disorders in the perioperative period of CABG.
About the Authors
Yu. V. Chugunova
Altay State Medical University, Barnaul;
Altay Regional Cardiological Dispensary, Barnaul
Russian Federation
Russian Federation
For correspondence: Chugunova Yulia Address: 46, Malakhova st.,Barnaul, 656055, Russian Federation Tel.: +7 (3852) 54-89-55 E-mail: julia.zykova@hotmail.com
G. A. Chumakova
Altay State Medical University, Barnaul
Russian Federation
Russian Federation
N. G. Veselovskaya
Altay State Medical University, Barnaul;
Altay Regional Cardiological Dispensary, Barnaul
Russian Federation
Russian Federation
References
1. Taggart D. P. Contemporary coronary artery bypass grafting. Frontiers in Medicine. 2014; 8 (4): 395–398. DOI: 10.1007/s11684-014-0374-7.
2. Джериева И. С., Волкова Н. И., Рапопорт С. И. Причинно-следственная связь между депрессией и синдромом ночной еды как предиктором абдоминального ожирения. РЖГГК. 2012; 1: 19–22. Dzheriyeva I. S., Volkova N. I., Rapoport S. I. Relationship of cause and effect between depression and night eating syndrome as predictor of abdominal obesity. RZhGGK. 2012; 1: 19–22. [In Russ.].
3. Ao H., Wang X., Xu F., Zheng Z., Chen M., Li L. et al. The impact of body mass index on shortand long-term outcomes in patients undergoing coronary artery graft bypass. PLoS One. 2014; 9 (4): 95223. DOI: 10.1371/journal.pone.0095223.
4. Чумакова Г. А., Веселовская Н. Г., Гриценко О. В., Отт А. В. Метаболический синдром: сложные и нерешенные проблемы. Российский кардиологический журнал. 2014; 3 (107): 63–71. Chumakova G. A., Veselovskaya N. G., Gritsenko O. V., Ott A. V. Metabolic syndrome: challenging and unresolved issues. Russ. J. Cardiol. 2014; 3 (107): 63–71. [In Russ.].
5. Yoon D. H., Choi S. H., Yu J. H., Ha J. H., Ryu S. H., Park D. H. The relationship between visceral adiposity and cognitive performance in older adults. Age and Ageing. 2012; 41 (4): 456–461. DOI: 10.1093/ageing/afs018.
6. Трубникова О. А., Тарасова И. В., Сырова И. Д., Мамонтова А. С., Малева О. В., Барбараш О. Л. Личностная тревожность как фактор риска когнитивных расстройств у пациентов, перенесших прямую реваскуляризацию миокарда. Российский кардиологический журнал. 2012; 4 (96): 25–29. Trubnikova O. A., Tarasova I. V., Syrova I. D., Mamontova A. S., Maleva O. V., Barbarash O. L. Trait anxiety as a risk factor of cognitive dysfunction in patients after myocardial revascularization. Russ. J. Cardiol. 2012; 4 (96): 25–29. [In Russ.].
7. Pizzi C., Santarella L., Manfrini O., Chiavaroli M., Agushi E., Cordioli E. et al. Ischemic heart disease and depression: an underestimated clinical association. G. Ital. Cardiol. (Rome). 2013; 14 (7–8): 526–537. DOI: 10.1714/1308.14461.
8. Gunstad J., Lhotsky A., Wendell C. R., Ferrucci L., Zondermanc A. B. Longitudinal examination of obesity and cognitive function: results from the Baltimore longitudinal study of aging. Neuroepidemiology. 2010; 34 (4): 222–229. DOI: 10.1159/000297742.
9. Веселовская Н. Г., Чумакова Г. А., Козаренко А. А., Бокслер М. И. Адипокины как корригируемые факторы риска сердечно-сосудистых заболеваний. Российский кардиологический журнал. 2010; 6: 88–93. Veselovskaya N. G., Chumakova G. A., Kozarenko A. A., Boxler M. I. Adipokines as a modifiable risk factors of cardiovascular disease. Russ. J. Cardiol. 2010; 6: 88–93. [In Russ.].
10. Tiehuis A. M., van der Graaf Y., Mali W. P., Vincken K., Muller M., Geerlings M. I.; SMART Study Group. Metabolic syndrome, prediabetes, and brain abnormalities on mri in patients with manifest arterial disease: the SMART-MR study. Diabetes Care. 2014; 37 (9): 2515–2521. DOI: 10.2337/dc140154.
11. Rasmussen L. S. Postoperative cognitive dysfunction: incidence and prevention. Best Practice and Research Clinical Anaesthesiology. 2006; 20: 315–330.
12. Трубникова О. А., Мамонтова А. С., Сырова И. Д., Кухарева И. Н., Малева О. В., Барбараш О. Л. Когнитивный статус пациентов после коронарного шунтирования при сахарном диабете 2-го типа. Клиническая медицина. 2015; 8: 39–44. Trubnikova O. A., Mamontova A. S., Syrova I. D., Kuhareva I. N., Maleva O. V., Barbarash O. L. Kognitivnyj status pacientov posle koronarnogo shuntirvoanija pri saharnom diabete 2-go tipa. Klinicheskaja medicina. 2015; 8: 39–44.
13. Krannich J. H., Tobias T., Broscheit J., Leyh R., Müllges W. Diabetes severely affects attentional performance after coronary artery bypass grafting. J. Cardiothorac. Surg. 2012; 7: 115. DOI: 10.1186/1749-8090-7-115.
14. Шишкова В. Н., Осыченко М. Е. Проблема когнитивного дефицита у пациентов с метаболическим синдромом. Consilium Medicum. 2011; 13 (10): 114–118. Shishkova V. N., Osychenko M. E. Problema kognitivnogo deficita u pacientov s metabolicheskim sindromom. Consilium Medicum. 2011; 13 (10): 114–118.
15. Загребаев Е. А., Искендеров Б. Г. Корреляция тревожно-депрессивных расстройств и сердечно-сосудистых событий у больных, перенесших аортокоронарное шунтирование. Материалы 2-го Международного образовательного форума «Российские дни сердца». Сборник тезисов. М.: 2014. Zagrebaev E. A., Iskenderov B. G. Korreljacija trevozhno-depressivnyh rasstrojstv i serdechno-sosudistyh sobytij u bol′nyh, perenesshih aortokoronarnoe shuntirovanie. Materialy 2-go Mezhdunarodnogo obrazovatel′nogo foruma «Rossijskie dni serdca». Sbornik tezisov. Moscow; 2014.
16. Bruce K. M., Yelland G. W., Smith J. A., Robinson S. R. Recovery of cognitive function after coronary artery bypass graft operations. Ann. Thorac. Surg. 2013; 95 (4): 1306–1313. DOI: 10.1016/j.athoracsur.2012.11.021.
17. Малкина-Пых И. Г. Психосоматика: Справочник практического психолога. М.; 2005. Malkina-Pyh I. G. Psihosomatika: Spravochnik prakticheskogo psihologa. Moscow; 2005.
18. Захаров В. В., Вахнина Н. В. Когнитивные нарушения при депрессии. Эффективная фармакотерапия. Неврология. 2015; 1 (1): 18–26. Zakharov V. V., Vakhnina N. V. Cognitive disorders during depression. Jeffektivnaja farmakoterapija. Nevrologija. 2015; 1 (1): 18–26. [In Russ.].
19. Pan A., Keum N., Okereke O. I., Sun Q., Kivimaki M., Rubin R. R. et al. Bidirectional association between depression and metabolic syndrome: a systematic review and metaanalysis of epidemiological studies. Diabetes Care. 2012; 35 (5): 1171–1180. DOI: 10.2337/dc11-2055.
Review
For citations:
Chugunova Yu.V., Chumakova G.A., Veselovskaya N.G. NEUROCOGNITIVE DISORDERS AMONG PATIENTS WITH VISCERAL OBESITY IN PERIOPERATIVE PERIOD OF CORONARY BYPASS SURGERY. Complex Issues of Cardiovascular Diseases. 2016;(3):59-65. (In Russ.) https://doi.org/10.17802/2306-1278-2016-3-59-65
Views:
835
