Preview

Complex Issues of Cardiovascular Diseases

Advanced search

COMORBIDITIES IN PATIENTS WITH CORONARY ARTERY DISEASE ADMITTED TO CARDIAC SURGERY CENTERS IN CHELYABINSK AND KEMEROVO

https://doi.org/10.17802/2306-1278-2017-6-4-71-79

Abstract

Aims. To estimate the detection rate of comorbidities in patients admitted for surgical treatment of coronary artery disease (CAD) and to compare surgical treatment options in two cardiac surgery centers.

Methods. All the patients older 18 years who underwent coronary artery bypass grafting in 2014 (isolated or combined coronary artery bypass grafting and heart valve repair or replacement and/or aneurysmectomy) admitted to the Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo (Kemerovo group; n =1166) and in the Federal Center for Cardiovascular Surgery, Chelyabinsk (Chelyabinsk group; n = 1293) were included in the study.

Results. The mean age of patients in the Kemerovo group was 62.5±7.8 years, and in the Chelyabinsk group 61.3±7.8 years (p <0.0001). There were significant differences in the incidence rate of postinfarction cardiosclerosis between Kemerovo and Chelyabinsk (66.7% vs. 85.6%, p<0.0001). Patients in the Kemerovo group commonly had obstructive pulmonary disease (13.9 vs 6.2%, p<0.0001), previous acute cerebrovascular accident (7.1 vs 4.6%, p<0.007), atherosclerosis oflower extremity arteries (10.7 vs 3.2%, p<0.0001), gastroduodenal ulcer (15.3 vs 11.0%, p<0.002) compared to patients in the Chelyabinsk group. On average, there are 0.6±0.02 of the above mentioned dis eases per one patient in Kemerovo and0.4±0.01 in Chelyabinsk (p<0.0001). Patients in the Kemerovo group commonly underwent stenting of coronary arteries (13.0 vs 9.9%, p<0.014) compared to patients in the Chelyabinsk group.

Each fourth patient underwent combined CABG and the other surgeries in Chelyabinsk, whereas in Kemerovo each sixth patient receivedcombined surgical treatment(p<0.0001). The number of combined CABG and left ventricular reconstruction was comparable in both centers.

The linear regression analysis reported that the du-ration of surgery and cardiopulmonary bypass time are statistically significantly associated with the performance of combined surgeries (p<0.0001), the presence of comorbidities (p<0.0001) and patient age (p<0.05).

Conclusion. Patients in the Kemerovo group commonly suffered from concomitant coronary artery disease, whereas patients in theChelyabinsk group were present with postinfarction cardiosclerosis. Each fourth patient underwent combined surgery in Chelyabinsk, whereas in Kemerovo each sixth patient received combined surgical treatment. The number of combined CABG and left ventricular reconstruction was comparable in both centers.

About the Authors

L. A. Efros
Federal State Budgetary Educational Institution of Higher Education «South-Ural State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Chelyabinsk


O. P. Lukin
Federal State Budgetary Institution «Federal Center for Cardiovascular Surgery»
Russian Federation

Chelyabinsk



I. V. Samorodskaya
Federal State Budgetary Institution «National Research Center for Preventive Medicine» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Moscow



V. Yu. Semenov
Federal State Budgetary Institution «A.N. Bakoulev Scientific Center for Cardiovascular Surgery» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Moscow



A. N. Sumin
Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»
Russian Federation

Kemerovo 



S. V. Ivanov
Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»
Russian Federation

Kemerovo 



M. V. Evseeva
Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»
Russian Federation

Evseeva Maria.

6, Sosnoviy blvd., Kemerovo, 650002, +7 (904) 96586 92



O. L. Barbarash
Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»; Federal State Budgetary Educational Institution of Higher Education «Kemerovo State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Kemerovo 



References

1. Cervera R., Bakaeen F., Cornwell L., Wang X.L., Coselli J.S., Surg. 2012;93(6):1950-1954.D0I:10.1016/j.athoracsur.2012.02.071 LeMaire S.A. et al. Impact of functional status on survival after

2. Weintraub W.S., Grau-Sepulveda M.V., Weiss J.M., O’Brien coronary artery bypass grafting in a veteran population. Ann. Thorac. S.M., Peterson E.D., Kolm P. et al. Comparative effectiveness of revascularization strategies.N Engl. J. 2012;366 (16): 1467-1476. D0I:10.1056/NEJMoa1110717

3. Sen B.B., Niemann B., Roth P., Aser R., Schonburg M., Boning A. Shortand long-term outcomes in octogenarians after coronary artery bypass surgery. Eur. J. Cardiothorac. Surg. 2012; 42 (5):102-107. D0I:10.1093/ejcts/ezs410

4. Saxena A., Dinh D., Smith J.A., Shardey G., Reid C.M., Newcomb A.E. Sex differences in outcomes following isolated coronary artery bypass graft surgery in Australian patients: analysis of the Australasian Society of Cardiac and Thoracic Surgeons cardiac surgery database. Eur. J. Cardiothorac. Surg. 2012; 41(4):755-762. DOI: https://doi.org/10.1093/ejcts/ezr039

5. Перхов В.И., Киреев А.Б., Ахмедов Ш.Д. История, реальность и перспективы обеспечения населения РФ бесплатной высокотехнологической медицинской помощью. Сибирский медицинский журнал.2009; 24(1): 63-66. [Perkhov V.I., Kireev A.B., Akhmedov Sh.D. History, reality and perspectives of rendering free of charge hightechnology medical aid for the population of russian federation. The Siberian medical journal. 2009. 24(1): 63-66. (In Russ)].

6. Nardi P., Pellegrino A., Scafuri A., Binaco I., Polisca P., Iorio F. etal. Long-term outcomes after surgical ventricular restoration and coronary artery bypass grafting in patients with postinfarction left ventricular anterior aneurysm. J. Cardiovasc. Med. (Hagerstown). 2010; 11 (2): 96-102.D0I:10.2459/JCM.0b013e32832f9fc1

7. Solodky A., Behar S., Boyko V., Battler A., Hasdai D. The outcome of coronary artery bypass grafting surgery among patients hospitalized with acute coronary syndrome: the Euro Heart Survey of acute coronary syndrome experience. Cardiology. 2005; 103: 44-47.

8. Fleisher LA. Preoperative assessment of the patient with cardiac disease undergoing noncardiac surgery. Anesthesiol. Clin. 2016; 34 (1):59-70.D0I: 10.1016/j.anclin.2015.10.006

9. Самородская И.В., Никифорова M.A. Терминология и методы оценки влияния коморбидности на прогноз и исходы лечения. Бюллетень НЦССХ им. АН. Бакулева РАМН. 2013; 14 (4): 18-26. [Samorodskaya I.V., Nikiforova M.A. Terminology and methods of assessment of influence of comorbidity on prognosis and outcomes of treatment. Byulleten’ A.N.Bakoulev Scientific Center for Cardiovascular Surgery of the Russian Academy of Medical Sciences.2013; 14 (4): 18-26. (InRuss)].

10. Бокерия Л.А., Ступаков И.Н., Самородская И.В., Болотова Е.В. Распространенность сопутствующих заболеваний у больных ишемической болезнью сердца, нуждающихся в кардиохирургическом лечении. Бюллетень НЦССХ им. А.Н. Бакулева РАМН. 2009; 10 (3): 46. [Bokeriya L.A., Stupakov I.N., Samorodskaya I.V., Bolotova E.V. The prevalence of comorbidities in patients with coronary heart disease who require cardiac surgery treatment. Byulleten’ A.N. Bakoulev Scientific Center for Cardiovascular Surgery of the Russian Academy of Medical Sciences.2009; 10 (3): 46. (InRuss)].

11. Ахмедов Ш.Д., Мотрева А.П., Роговская Ю.В., Кошельская О.А., Шипулин В.М. Сравнительная клинико-морфологическая оценка результатов хирургического лечения ИБС у больных сахарным диабетом 2 типа и у пациентов без нарушений углеводного обмена. Сибирский медицинский журнал. 2007; 22(3): 3438. [Akhmedov Sh.D., Motreva A.P., RogovskayaYu.V., Koshel’skaya O.A., Shipulin V.M. Comparative clinical-morphological estimation of results of surgical treatment IHD in patients with diabetes of type 2 and in patients without infringements of a carbohydrate. The Siberian medical journal. 2007; 22(3): 34-38. (In Russ)].

12. Тарасов P.C., Иванов C.B., Казанцев A.H., Бурков H.H., Ануфриев А.И., Зинец М.Г. и др. Госпитальные результаты различных стратегий хирургического лечения пациентов с сочетанным поражением коронарного русла и внутренних сонных артерий. Комплексные проблемы сердечно-сосудистых заболеваний. 2016; 4:15-24. D0I:10.17802/2306-1278-2016-4-15-24. [Tarasov R.S., Ivanov S.V., Kazantsev A.N., Burkov N.N., Anufriev A.I., Zinets M.G. et al. Hospital results of the different strategies of surgical treatment of patients with concomitant coronary disease and internal carotid arteries stenoses. Complex Issues of Cardiovascular Diseases. 2016; 4:15-24. D0I:10.17802/2306-1278-2016-4-15-24(In Russ)].

13. Никитин Ю.П., Воевода М.И., Симонова Г.И. Сахарный диабет и метаболический синдром в Сибири и на Дальнем Востоке. Вестник РАМН. 2012; 1:66-74. [Nikitin Yu.P., Voevoda M.I., Simonova G.I. Sakharnyy diabet i metabolicheskiy sindrom v Sibiri i na Dal’nem Vostoke. Vestnik RAMN. 2012; 1:66-74.(In Russ)].

14. Барбараш О.Л., Семенов В.Ю., Самородская И.В., Евсеева M.B., Рожков Н.А., Сумин А.Н. и др. Коморбидная патология у больных ишемической болезнью сердца при коронарном шунтировании: опыт двух кардиохирургических центров. Российский кардиологический журнал. 2017; (3):6-13. DOI: 10.15829/15604071-2017-3-6-13.[Barbarash0.L., Semenov V.Yu.,Samorodskaya I. V., Evseeva M.V., Rozhkov N.A., Sumin A.N. Comorbid conditions in patients with coronary artery disease undergoing coronary artery bypass grafting: dual center experience. RussJCardiol. 2017; (3):6-13. DOI: 10.15829/1560-4071-2017-3-6-13 (InRuss)].

15. Рекомендации по лечению стабильной ишемической болезни сердца. ESC 2013. Российский кардиологический журнал. 2014; 7(111): 7-79. [Recommendations on stable coronary artery disease treatment. ESC 2013. Russ J Cardiol. 2014; 7(111):7-79. (In Russ)].

16. DAgostino R.S., Jacobs J.P., Badhwar V., Paone G., Rankin J.S., Hanetal J.M. The Society of Thoracic Surgeons Adult Cardiac Surgery Database: 2016 Update on Outcomes and Quality. Ann Thorac Surg. 2016; 101: 24-32.DOI:10.1016/j.athoracsur.2015.11.032

17. Кочурова Л.В., Елисеев B.A. Множественность заболеваний у детей, проживающих в экологически неблагоприятных регионах Сибири. Экология человека. 2011; 11: 19-24. [Kochurova L.V., Eliseev V.A. Mnozhestvennost’ zabolevaniyudetey, prozhivayushchikh v ekologicheski neblagopriyatnykh regionakh Sibiri. Ekologiya cheloveka. 2011; 11: 19-24. (InRuss)].

18. Губанова В.Г., Беляева Ю.Н., Шеметова Г.Н. Коморбидный пациент: этапы формирования, факторы риска и тактика ведения. Современные проблемы науки и образования. 2015; 6:1-7. [ Gubanova V.G., BelyaevaYu.N., Shemetova G.N. Komorbidnyy patsient: etapy formirovaniya, factory riska i taktikavedeniya. Sovremennye problem nauki obrazovaniya. 2015; 6:1-7. (InRuss)].

19. Алекян Б.Г., Бузиашвили Ю.И., Голухова E.3., Бокерия О.Л., Никитина Т.Г., Петросян КВ и др. Непосредственные результаты чрескожных коронарных вмешательств у пациентов старше 80 лет с хронической ишемической болезнью сердца. Грудная и сердечно-сосудистая хирургия. 2014; 6:12-16. [Alekyan B. G., Buziashvili Yu.I., Golukhova E.Z., Bokeriya O.L., Nikitina T.G., Petrosyan K.V et al. Immediate results of percutaneous coronary interventions in patients older than 80 years with chronic ischemic heart disease. Thoracic and Cardiovascular Surgery. 2014; 6:12-16. (In Russ)].


Review

For citations:


Efros L.A., Lukin O.P., Samorodskaya I.V., Semenov V.Yu., Sumin A.N., Ivanov S.V., Evseeva M.V., Barbarash O.L. COMORBIDITIES IN PATIENTS WITH CORONARY ARTERY DISEASE ADMITTED TO CARDIAC SURGERY CENTERS IN CHELYABINSK AND KEMEROVO. Complex Issues of Cardiovascular Diseases. 2017;6(4):71-79. (In Russ.) https://doi.org/10.17802/2306-1278-2017-6-4-71-79

Views: 1229


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2306-1278 (Print)
ISSN 2587-9537 (Online)