Prevalence of coronary artery disease in the indigenous population of Gornaya Shoria (the results of epidemiological studies in 1998-2001 and 2013-2017)

Aim. To study the features of the prevalence of coronary heart disease (CHD) in the period 1998–2001 and 2013–2017 in the indigenous population of Gornaya Shoria.

Methods. In the first period of the study (from 1998 to 2001), 550 respondents of indigenous nationality living in rural areas of Gornaya Shoria (v. Orton and v. Ust-Kabyrza) were included. In the second period (from 2013 to 2017) – 937 people in the same villages, as well as in the urban village Sheregesh and city Tashtagol. The presence of coronary artery disease was estimated by the sum of three epidemiological criteria: based on the analysis of ECG by Minnesota code, Rose questionnaire and a history of myocardial infarction. Statistical analysis was performed using the program Statistica 6.0 (StatSoft Inc., USA.) Qualitative features were described using frequencies as a percentage. To determine the statistical significance of these differences, Pearson's criterion c2 was evaluated. In the study, the critical level of significance when testing statistical hypotheses was taken p<0.05.

Results. The frequency of CHD in the first stage of the study in the village was 6.2%, in the survey of the rural population in the Gornaya Shoria in 2013–2017 this figure was 8.0%. Comparative analysis at the second stage of the study showed a higher prevalence of this disease among urban residents (12.6%) compared with rural (8.0%, p = 0.048). These differences reach statistical significance due to the female population in the age groups of 40–49 years and 50–59 years (7.1% vs. 0% (p = 0.051) and 15.4% vs. 4.1% (p = 0.031)). In males living in the city, revealed an earlier debut of CHD in 40–49 years (5.6%).

Conclusion. The study revealed an increase in the prevalence of CHD in women in the indigenous small population of Gornaya Shoria from 1998–2001 to 2013–2017, as well as a number of significant statistically significant differences in the frequency of CHD among the urban and rural population.

1. Oganov R.G. Demographic tendencies in the Russian Federation: contribution of diseases of the blood circulatory system. Cardiovascular Therapy and Prevention. 2012; 11 (1): 5–10 (in Russian).

2. Nagibina Yu.V., Zakharova L.A. Life quality, medical and social characteristics of coronary heart disease patients. Russ J Cardiol. 2017; 3 (143): 155–9. doi:10.15829/1560-4071-20173-155–9 (in Russian).

3. Shlyakhto E.V., Sergeeva Е.G., Berkovich О.А., Pchelina S.N., Zarayskiy М.I., Ionova Zh.I., Polyakova Е.А., Baranova Е.I. Predictors of adverse clinical course of coronary heart disease: the results from dynamical observation. Russ J Cardiol. 2018; 23 (7): 60–6. doi:10.15829/1560-4071-2018-7-60-66 (in Russian).

4. Akimova Е.V., Kayumova М.М., Gakova E.I., Smaznova O.V., Gafarov V.V., Smaznov V.Yu., Kuznetsov V.A. Relationship between the prevalence of coronary artery disease and attitude towards prevention and treatment in open urban male population. Siberian medical journal (Tomsk). 2012; 2: 153-6 (in Russian).

5. Huijgen R., Hutten B.A., Kindt I., Vissers M.N., Kastelein J.J. Discriminative ability of LDL-cholesterol to identify patients with familial hypercholesterolemia: a cross-sectional study in 26,406 individuals tested for genetic FH. Circ Cardiovasc Genet. 2012; 5 (3): 354–9. doi: 10.1161/CIRCGENETICS.111.962456.

6. Kontsevaya A.V., Myrzamatova A.O., Polupanov A.G., Alikhanova K.A., Kashirin A.K., Khalmatov A.N., Altymysheva A.T., Iskakov E.B., Balanova Y.A., Dzhumagulova A.S. Ethnic specifics of the main cardiovascular risk factors prevalence among rural inhabitants of a Russian region and regions of Kyrgyzstan and Kazakhstan. Russian Journal of Cardiology. 2017; 6: 113–121. doi:10.15829/1560-4071-2017-6-113-121 (in Russian).

7. Sulejmanov H.B., Irgasheva U.Z. Frequency of some risk factors among patients with coronary heart disease. Tyumen medical journal. 2011; 2: 10 (in Russian).

8. Oommen A.M., Abraham V.J., George K., Jose V.J. Prevalence of coronary heart disease in rural and urban Vellore: A repeat cross-sectional survey. Indian Heart J. 2016; 68 (4): 473–9. doi: 10.1016/j.ihj.2015.11.015.

9. Htet A.S., Bjertness M.B., Sherpa L.Y., Kjollesdal M.K., Oo W.M., Meyer H.E., Stigum H., Bjertness E. Urban-rural differences in the prevalence of non-communicable diseases risk factors among 25-74 years old citizens in Yangon Region,Myanmar: a cross sectional study. BMC Public Health. 2016; 16 (1): 1225. doi:10.1186/s12889-016-3882-3.

10. Ogarkov M.Yu., Barbarash O.L., Polikutina O.M., Kvitkova L.V., Kazachek Ya.V., Baum V.A., Yudin N.S., Shakhtshneyder E.V., Barbarash L.S. Abundance of an ischemic heart disease at indigenous and not indigenous people of Gornaya Shoriya. Bulletin SO RAMN. 2003; 2 (108): 58–63 (in Russian).

11. Belyalov F.I. The specifics of ischemic heart disease management in elderly. Russian Journal Cardiology. 2017; 3 (143): 72–6. doi:10.15829/1560-4071-2017-3-72-76 (in Russian).

12. Heidenreich P.A., Trogdon J.G., Khavjou O.A., Butler J., Dracup K., Ezekowitz M.D. et al. Forecasting the future of cardiovascular disease in the United States a policy statement from the American Heart Association. Circulation. 2011; 123: 933–44. doi: 10.1161/CIR.0b013e31820a55f5.

13. Hripunova A.A., Hripunova I.G., Maksimenko L.L., Ivanina A.P. Regional features of epidemiology of coronary heart disease taking into account gender and age distinctions. Modern problems of science and education. 2017; 6. Available at: http://science-education.ru/ru/article/view?id=27175 (accessed: 09.04.2018) (in Russian).

14. Amlaev K.R., Ajbazov R.U., Zafirova V.B. The analysis of incidence of an ischemic heart disease and resource providing a medical care to cardiological patients in the North Caucasian Federal District and the Karachay-Cherkess Republic. Kuban scientific medical bulletin. 2014; 5 (147): 7–14 (in Russian).

15. Shcherbakov D.V., Nelidova A.V., Usacheva E.V., Romanov A.A., Bunova S.S. Dynamics and structure of incidence of coronary heart disease in the Omsk region. Modern problems of science and education. 2017; 5. Available at: http://science-education.ru/ru/article/view?id=26802 (accessed: 09.04.2018) (in Russian).

16. Mihalina E.V., Mulerova T.A., Kuzmina A.A., Ogarkov M.Yu., Trubacheva I.A. Risk factors for coronary heart disease among urban and rural population of Mountain Shoria. Complex Issues of Cardiovascular Diseases. 2017; 2: 79–86. doi:10.17802/2306-1278-2017-2-79-86 (in Russian).

17. Rylskaya T.V., Shalygina L.S., Bedoreva I.Y., Ivaninskiy O.I., Sharapov I.V., Finchenko E.A. Comparative analysis of morbidity and mortality in urban and rural population from diseases of the circulatory system in the Novosibirsk region. Social aspects of health of the population. Available at: http://vestnik.mednet.ru/content/view/605/30/lang,ru/ (accessed: 09.04.2018) (in Russian).