The journal "Complex Issues of Cardiovascular Diseases" was established in 2012 at the initiative of co-workers of RI for CICVD. The main reason of its establishment was the accumulation of a large amount of scientific researches and the need of their transmission to the real clinical practice. Moreover the purpose of the journal’s establishment – the rationale and discussion of a number of key breakthrough researches in the field of medical biotechnologies (personalized diagnosticums, new models of bioprosthesis of cardiovascular system structures, etc). lishment – the rationale and discussion of a number of key breakthrough researches in the field of medical biotechnologies (personalized diagnosticums, new models of bioprosthesis of cardiovascular system structures, etc).