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CORRECTION OF COMPLICATIONS AFTER STENT GRAFT IMPLANTATION: TWO APPROACHES TO THE CORRECTION OF ENDOLEAKS AND INFECTIONS USING HOMOGRAFTS

https://doi.org/10.17802/2306-1278-2025-14-3-203-212

Abstract

Highlights

This study makes a significant contribution to the field of endovascular treatment of aortic aneurysms by examining two approaches to managing complications such as endoleaks and stent graft infections. For the first time, the use of cryopreserved homografts for treating stent graft infections is presented, demonstrating a reduced risk of recurrent infection and improved long-term outcomes. The study highlights the importance of timely diagnosis and an individualized approach in addressing complications following stent graft implantation.

 

Abstract

Endovascular aortic repair (EVAR) using stent grafts has become the gold standard in the treatment of aortic aneurysms, significantly reducing surgical invasiveness. However, it may be associated with serious complications such as endoleaks and stent graft infections. This article presents two clinical cases. In the first case, a 55-year-old female patient developed a type I endoleak due to incomplete apposition of the stent graft to the aortic wall. Surgical correction was performed with resection of the affected segments and replacement of the aortic arch and its branches. In the second case, a 61-year-old male developed a stent graft infection following thoracic EVAR. The infected graft was explanted, and a cryopreserved homograft was implanted to reduce the risk of reinfection. Both patients had successful outcomes with an uncomplicated postoperative course. These cases illustrate the importance of timely diagnosis and a personalized approach to managing EVAR complications. The use of homografts in infected fields proved effective in preventing recurrent infection and improving long-term outcomes. Our experience supports the effectiveness of these surgical strategies in complex clinical scenarios requiring individualized treatment.

About the Authors

Roman N. Komarov
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

PhD, Professor, Head of the Department of Cardiovascular Surgery at the Institute of Professional Education, Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Maxim I. Tkachev
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

PhD, Associate Professor at the Department of Cardiovascular Surgery at the Institute of Professional Education, Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Ilyas D. Gailaev
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

4th-year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Georgy A. Varlamov
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

4th-year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Diana V. Manashirova
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

6th -year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Egor D. Chukov
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

6th-year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Artemiy S. Boyko
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

6th -year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Anastasia S. Ostrovskaya
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

6th-year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Artem S. Artemenko
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

6th-year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



Nikita M. Veselov
Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

6th-year student at the Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation



References

1. Deniz G, Kasımzade F, Ozcınar E, Yazicioglu L, Eryılmaz S. Long-term outcomes of TEVAR for thoracic aortic diseases: a retrospective single-center study. J Cardiothorac Surg. 2024;19(1):405. doi:10.1186/s13019-024-02886-6

2. Awiwi MO, Kandemirli VB, Kokash D, et al. Complications of thoracic endovascular aneurysm repair (TEVAR): A pictorial review. Current Problems in Diagnostic Radiology. 2024;53(5):648-661. doi:10.1067/j.cpradiol.2024.05.018

3. Langer S, Mommertz G, Koeppel TA, Schurink GWH, Autschbach R, Jacobs MJ. Surgical correction of failed thoracic endovascular aortic repair. Journal of Vascular Surgery. 2008;47(6):1195-1202. doi:10.1016/j.jvs.2008.01.003

4. Hobbs SD, Kumar S, Gilling-Smith GL. Epidemiology and diagnosis of endograft infection. J Cardiovasc Surg (Torino). 2010;51(1):5-14.

5. Bockeria L.A., Abdulgasanov R.A., Gasymov E.G., Arakelyan V.S. Prosthetic infection of the descending thoracic aorta: methods of diagnosis and treatment. Russian Annals of Surgery. 2019; 24 (5): 307–19 (in Russ.).

6. Popov VA, A. V. Vishnevsky Institute of Surgery, Korostelev AN, et al. The Case of Successful Surgical Treatment of a Patient With Thoracic Endograft Infection in 5 Years After Thoracic Endovascular Aortic Repair. CARDIO. 2018;17(4):96-100. doi:10.18087/cardio.2018.4.10115

7. Corvera JS, Fehrenbacher JW. Total arch and descending thoracic aortic replacement by left thoracotomy. Ann Thorac Surg. 2012;93(5):1510-1515; discussion 1515-1516. doi:10.1016/j.athoracsur.2012.01.098

8. Gopaldas RR, Huh J, Dao TK, et al. Superior nationwide outcomes of endovascular versus open repair for isolated descending thoracic aortic aneurysm in 11,669 patients. J Thorac Cardiovasc Surg. 2010;140(5):1001-1010. doi:10.1016/j.jtcvs.2010.08.007

9. Nozdrzykowski M, Luehr M, Garbade J, et al. Outcomes of secondary procedures after primary thoracic endovascular aortic repair. Eur J Cardiothorac Surg. 2016;49(3):770-777. doi:10.1093/ejcts/ezv279

10. Makaroun MS, Dillavou ED, Wheatley GH, Cambria RP. Five-year results of endovascular treatment with the Gore TAG device compared with open repair of thoracic aortic aneurysms. Journal of Vascular Surgery. 2008;47(5):912-918. doi:10.1016/j.jvs.2007.12.006

11. Scurto L, Peluso N, Pascucci F, et al. Type 1A Endoleak after TEVAR in the Aortic Arch: A Review of the Literature. J Pers Med. 2022;12(8):1279. doi:10.3390/jpm12081279

12. Ameli-Renani S, Pavlidis V, Morgan RA. Secondary Endoleak Management Following TEVAR and EVAR. Cardiovasc Intervent Radiol. 2020;43(12):1839-1854. doi:10.1007/s00270-020-02572-9

13. Ricotta JJ. Endoleak management and postoperative surveillance following endovascular repair of thoracic aortic aneurysms. J Vasc Surg. 2010;52(4 Suppl):91S-9S. doi:10.1016/j.jvs.2010.06.149

14. Saleem BR, Meerwaldt R, Tielliu IFJ, Verhoeven ELG, van den Dungen JJAM, Zeebregts CJ. Conservative treatment of vascular prosthetic graft infection is associated with high mortality. Am J Surg. 2010;200(1):47-52. doi:10.1016/j.amjsurg.2009.05.018

15. Murphy EH, Szeto WY, Herdrich BJ, et al. The management of endograft infections following endovascular thoracic and abdominal aneurysm repair. J Vasc Surg. 2013;58(5):1179-1185. doi:10.1016/j.jvs.2013.04.040

16. Setacci C, de Donato G, Setacci F. Endografts for the treatment of aortic infection. Semin Vasc Surg. 2011;24(4):242-249. doi:10.1053/j.semvascsurg.2011.10.009

17. Fatima J, Duncan AA, de Grandis E, et al. Treatment strategies and outcomes in patients with infected aortic endografts. J Vasc Surg. 2013;58(2):371-379. doi:10.1016/j.jvs.2013.01.047

18. Canaud L, Alric P, Gandet T, Ozdemir BA, Albat B, Marty-Ane C. Open surgical secondary procedures after thoracic endovascular aortic repair. Eur J Vasc Endovasc Surg. 2013;46(6):667-674. doi:10.1016/j.ejvs.2013.08.022

19. Lyons OTA, Patel AS, Saha P, Clough RE, Price N, Taylor PR. A 14-year experience with aortic endograft infection: management and results. Eur J Vasc Endovasc Surg. 2013;46(3):306-313. doi:10.1016/j.ejvs.2013.04.021

20. Petrunić M, Biočina B, Uzun S, Meštrović T, Šafradin I. Cryopreserved aortic homograft for in situ replacement of infected thoracic stent graft associated with distal aortic arch rupture and hematemesis. Ann Thorac Surg. 2014;98(6):2219-2221. doi:10.1016/j.athoracsur.2014.01.069

21. Sodha NR. Complex homograft aortic reconstruction: New recipes from old ingredients. The Journal of Thoracic and Cardiovascular Surgery. 2017;153(5):e77-e79. doi:10.1016/j.jtcvs.2017.01.027

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For citations:


Komarov R.N., Tkachev M.I., Gailaev I.D., Varlamov G.A., Manashirova D.V., Chukov E.D., Boyko A.S., Ostrovskaya A.S., Artemenko A.S., Veselov N.M. CORRECTION OF COMPLICATIONS AFTER STENT GRAFT IMPLANTATION: TWO APPROACHES TO THE CORRECTION OF ENDOLEAKS AND INFECTIONS USING HOMOGRAFTS. Complex Issues of Cardiovascular Diseases. 2025;14(3):203-212. (In Russ.) https://doi.org/10.17802/2306-1278-2025-14-3-203-212

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