EFFECT OF POLYVASCULAR DISEASE ON QUALITY OF LIFE OF CORONARY ARTERY DISEASE PATIENTS
https://doi.org/10.17802/2306-1278-2014-1-36-41
Abstract
Purpose. To study the effect of polyvascular disease (PolyVD) on quality of life (QoL) of coronary artery disease (CAD) patients.
Materials and methods. We examined 807 CAD patients (59,0 ± 8,0 years old; 648 men and 159 women), who were examined before planned coronary artery bypass surgery (CABG). The patients were additionally examined for subclinical stenosis of non-coronary arteries to identify the signs of PolyVD (artery stenosis 30% and more were included). The following groups were formed: PolyVD group (n = 336) and non-PolyVD group (n = 473). The groups were compared in terms of quality of life and depression. QoL was analyzed with the help of SF36 questionnaire, depression level – with the help of “Depression scale” questionnaire.
Results. In PolyVD group integral indicators of QoL were lower compared to non-PolyVD group both as for physical component (69 (51,5;72,3) and 71,3 (61,3;75,8) points; р = 0,004), and for psychological component (62.8 (48.5, 72.0) and 63.5 (57.0, 72.8) points, p = 0.045) of QoL. In multiple regression analysis the independent effect on physical component of QoL was provided by PolyVD (OR = 0,679; 95%CI 0,477–0,966; р = 0,031) and functional class of CHF (OR = 0,514; 95%CI 0,378–0,698; р < 0,001), on psychological component – functional class of CHF (OR = 0,577; 95%CI 0,425–0,784; р<0,001).
Conclusion. CAD patients with PolyVD as compared to patients with discrete lesion of coronary arteries have a higher level of depression and reduce of quality of life both as for certain scales of SF-36 questionnaire and integral indicators of physical and psychological components of QoL. In multivariate analysis the independent factors associated with a reduction in overall physical health were PolyVD presence and CHF severity, associated with a reduction in overall psychological health – only CHF severity.
About the Authors
A. N. Sumin
Federal State Budgetary Institution Research Institute for Complex Problems of Cardiovascular Diseases, Siberian Department of Russian Academy of Medical Sciences, Kemerovo
Russian Federation
Russian Federation
M. G. Moskin
Federal State Budgetary Institution Research Institute for Complex Problems of Cardiovascular Diseases, Siberian Department of Russian Academy of Medical Sciences, Kemerovo
Russian Federation
Russian Federation
A. V. Bezdenezhnyh
Federal State Budgetary Institution Research Institute for Complex Problems of Cardiovascular Diseases, Siberian Department of Russian Academy of Medical Sciences, Kemerovo
Russian Federation
Russian Federation
senior research associate of blood circulation pathology laboratory
Correspondence address:
6, Sosnoviy blvd., Kemerovo, 650002. Tel. +7 (3842) 64-44-61
E. V. Korok
Federal State Budgetary Institution Research Institute for Complex Problems of Cardiovascular Diseases, Siberian Department of Russian Academy of Medical Sciences, Kemerovo
Russian Federation
Russian Federation
A. V. Scheglova
Federal State Budgetary Institution Research Institute for Complex Problems of Cardiovascular Diseases, Siberian Department of Russian Academy of Medical Sciences, Kemerovo
Russian Federation
Russian Federation
References
1. Возможность использования модифицированной шкалы EUROSCORE для оценки годового прогноза коронарного шунтирования у пациентов с мультифокальным атеросклерозом / Л. С. Барбараш [и др.] // Патология кровообращения и кардиохирургия. 2010. № 2. С. 52–56.
2. Личностный тип Д у больных мультифокальным атеросклерозом: распространенность, влияние на качество жизни / А. Н. Сумин [и др.] // Креативная кардиология. 2010. № 2. С. 123–133.
3. Распространенность и клиническая значимость мультифокального атеросклероза у пациентов с инфарктом миокарда и подъемом сегмента ST / Л. С. Барбараш [и др.] // Кардиология и сердечно-сосудистая хирургия. 2010. № 5. С. 31–36.
4. Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery / B. Phillips-Bute [et al.] // Psychosom Med. 2006. Vol. 68. P. 369–375.
5. Asymptomatic carotid artery stenosis and cognitive outcomes after coronary artery bypass grafting / I. Norkienė [et al.] // Scand. Cardiovasc. J. 2011. Vol. 45 P. 169–173.
6. Cognition and quality of life in patients with carotid artery occlusion: a follow-up study / F. C. Bakker [et al.] // Neurology. 2004. Vol. 62. P. 2230–2235.
7. Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis / D. L. Bhatt [et al.] // JAMA. 2010. Vol. 304. P. 1350–1357.
8. Health-related quality of life among patients with symptomatic carotid disease / H. Vlajinac [et al.] // Postgrad. Med. J. 2012. Oct 5. [Epub ahead of print].
9. Health-related quality of life predicts long-term survival in patients with peripheral artery disease / S. M. Issa [et al.] // Vasc. Med. 2010. Vol. 15. P. 163–169.
10. Long-term prognosis of patients with peripheral arterial disease with or without polyvascular atherosclerotic disease / J. P. van Kuijk [et al.] // Eur. Heart J. 2010. Vol. 31. P. 992–999.
11. Low ankle-brachial index predicts early risk of recurrent stroke in patients with acute cerebral ischemia / G. Tsivgoulis [et al.] // Atherosclerosis. 2012. Vol. 220. P. 407–412.
12. Quality of life of patients with peripheral arterial disease and chronic stable angina / W. R. Wilson [et al.] // Angiology. 2012. Vol. 63. P. 223–228.
13. Subclinical peripheral arterial disease and incompressible ankle arteries are both long-term prognostic factors in patients undergoing coronary artery bypass grafting / V. Aboyans [et al.] // J. Am. Coll. Cardiol. 2005. Vol. 46. P. 815–820.
14. The impact of peripheral arterial disease on healthrelated quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) Program / J. G. Regensteiner [et al.] // Vasc. Med. 2008. Vol. 13. P. 15–24.
15. The role of carotid intima-media thickness assessment in cardiovascular risk evaluation in patients with polyvascular atherosclerosis / A. Kablak-Ziembicka [et al.] // Atherosclerosis. 2010. Vol. 209. P. 125–130.
16. Тrubnikоvа O., Tarasova I., Barbarash O. Impact of low and moderate carotid stenoses on neurophysiological status of patients undergoing on-pump coronary artery bypass grafting // Frontiers neurology. 2012. Vol. 3. P. 1–5.
Review
For citations:
Sumin A.N., Moskin M.G., Bezdenezhnyh A.V., Korok E.V., Scheglova A.V. EFFECT OF POLYVASCULAR DISEASE ON QUALITY OF LIFE OF CORONARY ARTERY DISEASE PATIENTS. Complex Issues of Cardiovascular Diseases. 2014;(1):36-41. (In Russ.) https://doi.org/10.17802/2306-1278-2014-1-36-41
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