MYOCARDIAL INFARCTION IN YOUNG PATIENTS: LONG-TERM ANALYSIS Of SPECIFICITY Of APPEARANCE, CLINICAL COURSE AND STRATEGIES Of MANAGEMENT

Purpose. To study the dynamics of the emergence and clinical course of acute myocardial infarction (AMI) in young patients and to compare the changes in treatment strategies at various time intervals in this age group patients.

Materials and methods. Selection of clinical material was carried out as a continuous sample from the database of the «Acute Myocardial Infarction Registry» (AMIR). Inclusion criteria: young patients (younger than 45 years) suffered from acute myocardial infarction (AMI). All favorable outcomes were studied separately: 69 clinical cases in 2005–2007, and 109 episodes in 2012–2014.

Results. The history of young patients was burdened. AMI was manifested with typical heart attack in more than 90 % of cases in both time intervals. The duration of the period of «pain-hospital» remained the same, despite the significant reduction of time delays at the stage of «pain-call the ambulance». The majority of young patients with AMI were hospitalized in a specialized cardiology departments: in recent years, the proportion of such patients substantially increased (from 85.5 to 95.4 %, p=0.04). Vital medicines were recommended to the majority of young patients at discharge from hospitals, and the frequency of their assignment had increased.

Conclusion. The frequency of AMI in young patients has not significantly changed, as well as the gender composition. AMI was occurred on the background of diabetes mellitus in young patients. The establishment of vascular centres and primary hospitalization of young patients to specialized medical institutions has contributed to a significant intensification of interventions in the acute period of MI.

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