NEUROPSYCHOLOGICAL STATUS OF PATIENTS WITH STABLE CORONARY ARTERY DISEASE AND FACTORS AFFECTING IT
https://doi.org/10.17802/2306-1278-2017-1-112-121
Abstract
The purpose. To assess neuropsychological status of patients with stable coronary artery disease (CAD) and to determine the factors affecting it.
Material and methods. 272 male patients aged 45-69 years were included in the study. Neuropsychological status of patients with coronary artery disease was assessed and presented as an integrated index.
Results. The integrated index of neuropsychological status was reported to be 2 times less than those in healthy subjects matched for age (0.47 [0.35; 0.59] vs. 0.8 [0.72; 0.87, (p <0.0001)). The most significant factors affecting neuropsychological status of patients with coronary artery disease were as follows: age (p = 0.00271), number of years of education (p = 0.033), left ventricular ejection fraction (LVEF) (p = 0.018), as well as plasma triglyceride levels (TG) (p = 0.003).
Conclusion. The integrated approach to the assessment of neuropsychological status in patients with CAD allows not only presenting it as a single index, but also determining the extent to which the index deviate from neuropsychological status of healthy subjects. The factors affecting neuropsychological status in patients with coronary artery disease were as follows: age, number of years of education, LVEF and plasma triglyceride levels.
About the Authors
O. A. TRUBNIKOVA
Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”
Russian Federation
Russian Federation
6, Sosnoviy blvd., Kemerovo, 650002, Russian Federation Tel. +7(3842)643153
E. S. KAGAN
Federal State Budgetary Educational Institution of Higher Professional Education “Kemerovo State University”
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
T. V. KUPRIYANOVA
Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
O. V. MALEVA
Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
Y. A. ARGUNOVA
Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
I. N. KUKHAREVA
Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Disease”
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
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Review
For citations:
TRUBNIKOVA O.A., KAGAN E.S., KUPRIYANOVA T.V., MALEVA O.V., ARGUNOVA Y.A., KUKHAREVA I.N. NEUROPSYCHOLOGICAL STATUS OF PATIENTS WITH STABLE CORONARY ARTERY DISEASE AND FACTORS AFFECTING IT. Complex Issues of Cardiovascular Diseases. 2017;(1):112-121. (In Russ.) https://doi.org/10.17802/2306-1278-2017-1-112-121
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