SURVIVAL AFTER SURGICAL TREATMENT OF MULTIFOCAL ATHEROSCLEROSIS IN DIFFERENT AGE GROUPS
https://doi.org/10.17802/2306-1278-2017-2-6-18
Abstract
The purpose: Conducting the analysis of survival after surgery and the study of factors associated with mortality in patients with multifocal atherosclerosis (MFA) in diferent age groups.
Material and methods. It were included 764 consecutive patients aged 39 to 84 years with the MFA, who underwent isolated coronary artery bypass grafting (CABG) or CABG in combination with simultaneous or staged surgical interventions in the non-coronary vascular beds. The treatment procedure was determined by the heart team. Depending on the age of patients formed 4 groups: Group 1 - patients up to 60 years (n = 338), 2 group - 60-64 years (n = 185), 3 group - 65-69 years (n = 137) and group 4 - patients 70 years and older (n = 104).
Results. Analysis of hospital mortality after CABG surgery showed no signifcant diference between the groups, despite its increase among patients older than 65 years (p = 0.373). A similar trend was observed for remote mortality rates without statistical signifcance between the groups. Survival analysis showed no diference between groups in the time to onset of death (p = 0.205), the proportion of survivors over the period of observation in all groups was more than 75%. The regression survival Cox model showed that, in time before the fatal outcome after revascularization surgery were signifcantly associated female gender (p = 0.009), presence of diabetes mellitus (p = 0.003), stroke history (p = 0.002), the risk of surgical intervention on a scale EuroSCORE (p = 0.011) and left ventricular ejection fraction (p = 0.008).
Conclusion. Advanced age in combination with the MFA is a marker of increased mortality after revascularization surgery; however, these patients have favorable results on the long-term survival after staged surgery
About the Authors
R. A. Gajfulin
Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
6, Sosnoviy blvd., Kemerovo, 650002, Russian Federation
Russian Federation
6, Sosnoviy blvd., Kemerovo, 650002, Russian Federation
A. N. Sumin
Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
S. V. Ivanov
Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
L. S. Barbarash
Federal State Budgetary Institution Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Kemerovo, Russia
Russian Federation
Kemerovo, Russia
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For citations:
Gajfulin R.A., Sumin A.N., Ivanov S.V., Barbarash L.S. SURVIVAL AFTER SURGICAL TREATMENT OF MULTIFOCAL ATHEROSCLEROSIS IN DIFFERENT AGE GROUPS. Complex Issues of Cardiovascular Diseases. 2017;(2):6-18. (In Russ.) https://doi.org/10.17802/2306-1278-2017-2-6-18
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