DYSUNCTION OF RESPIRATORY SYSTEM IN PATIENTS WITH CORONARY ARTERY DISEASE AFTER PLANNED CORONARY ARTERY BYPASS GRAFTING

The purpose. Analysis of the dynamics of respiratory function indicators in patients with coronary artery disease (CAD) and comorbid bronchopulmonary pathology (BPP) who underwent coronary artery bypass grafting under cardiopulmonary bypass (CB).
Materials and methods. We examined 662 patients with CAD admitted for planned CABG. The formation of groups was based on the presence criteria of BPP and broncho-obstructive type of ventilatory disorders. Group 1 included 48 (7.2%) patients with BPP without obstructive disorders, group 2 – 248 (37.5%) patients with BPP who have respiratory obstruction, group 3 – 366 (55.3%) patients with the isolated CAD. The analysis of the dynamics of respiratory system function was based on the deviation from the due values as well as on the deviation of recoded respiratory parameters, which form the basis of comprehensive assessment of respiratory function.
Results. In the postoperative periodall the patients showed a decrease of all respiratory parameters. Statistically
lower parameters were observed in patients who had broncho-obstructive syndrome. To a greater extent (for more than 15% from the baseline) we registered a decrease in forced and slow vital lung capacity, total lung capacity, forced expiratory volume in 1 second, as well as diffusing capacity, to a lesser extent –intrathoracic and residual volumes. When comparing the similar respiratory parameters, basing on their recoding, statistically marked decrease was observed in patients who had a respiratory disease (the 1st and the 2nd groups) as compared to the patients with isolated CAD.
Conclusion. After CABG under CB there was a decrease of all the indicators which characterize pulmonary function, a more pronounced decrease was noticed in the level of forced and slow vital lung capacity and forced expiratory volume in 1 second. Interpretation of the dynamic changes of the recoded indicators showed an advantage over the traditional analysis based on the deviation from the due values.

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