QUANTITATIVE ASSESSMENT OF VISCERAL ADIPOSE DEPOT IN PATIENTS WITH ISCHEMIC HEART DISEASE BY USING OF MODERN TOMOGRAPHIC METHODS
https://doi.org/10.17802/2306-1278-2017-6-3-113-119
Abstract
Abstract. The aim of the study was a quantitative assessment of abdominal and epicardial depot visceral adipose tissue with the use of modern methods of tomography in patients with stable coronary heart disease (CHD).
Material and methods. 88 patients were examined with multislice computed and magnetic resonance tomography.
Results. According to a survey of abdominal visceral obesity was observed in 70.4% of the sample of patients and only 35.2% identified BMI. In patients with CHD severity of abdominal and epicardial visceral obesity is not dependent on sex. Separating patients under standard boundary values of visceral fat area (130sm²) revealed significant differences in the layer thickness of both the left epicardial fat (p = 0.00015) and right ventricle (p = 0.00126).
Conclusion. Approaches to the definition of obesity, currently used underestimate the true prevalence of this pathology. Morphometric evaluation of visceral fat depot using tomographic techniques can reliably and noninvasively verify adipose tissue and highlight the category of patients with visceral obesity.
About the Authors
A. N. Kokov
Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
Kemerovo
Russian Federation
Kemerovo
N. K. Brel
Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
6, Sosnoviy blvd., Kemerovo, 650002
Russian Federation
6, Sosnoviy blvd., Kemerovo, 650002
V. L. Masenko
Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
Kemerovo
Russian Federation
Kemerovo
O. V. Gruzdeva
Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
Kemerovo
Russian Federation
Kemerovo
V. N. Karetnikova
State Budgetary Educational Institution of Higher Professional Education Kemerovo State Medical University Ministries of Health of the Russian Federation
Russian Federation
Kemerovo
Russian Federation
Kemerovo
V. V. Kashtalap
Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
Kemerovo
Russian Federation
Kemerovo
O. L. Barbarash
Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
Kemerovo
Russian Federation
Kemerovo
References
1. Ожирение в России: статистические данные [Электронный ресурс]. 2013; Режим доступа: http://health.passion.ru/novosti-zdorovya/lishniives/ozhirenie-v-rossii-statisticheskie-dannye.htm. Ozhirenie v Rossii: statisticheskie dannye [Elektronnyj resurs]. 2013; Rezhim dostupa: http://health.passion.ru/novosti-zdorovya/lishnii-ves/ozhirenie-v-rossii-statisticheskie-dannye.htm. [In Russ].
2. Бондаренко В.М., Марчук В.П., Пиманов С.И., Михайлова Н.А., Макаренко Е.В. Корреляция содержания висцеральной жировой ткани по данным компьютерной томографии с антропометрическими показателями и результатами ультразвукового исследования. Вестник Витебского государственного медицинского университета. 2013; 1: 31-38. Bondarenko V.M., Marchuk V.P., Pimanov S.I., Mikhaylova N.A., Makarenko E.V. Korrelyatsiya soderzhaniya vistseral’noy zhirovoy tkani po dannym komp’yuternoy tomografii s antropometricheskimi pokazatelyami i rezul’tatami ul’trazvukovogo issledovaniya. Vestnik Vitebskogo gosudarstvennogo meditsinskogo universiteta. 2013; 1: 31-38. [In Russ].
3. Груздева О.В., Акбашева О.Е., Бородкина Д.А., Каретникова В.Н., Дылева Ю.А., Коков А.Н. и др. Взаимосвязь показателей ожирения и адипокинов с риском развития сахарного диабета 2-го типа через год после перенесенного инфаркта миокарда. Российский кардиологический журнал. 2015; 4: 59-67. DOI:10.15829/1560-4071-2015-4-59-67. Gruzdeva O.V., Akbasheva O.E., Borodkina D.A., Karetnikova V.N., Dyleva Y.A., Kokov A.N. et al. Relationship of obesity parameters and adipokines with the risk of 2nd type diabetes development in a year after myocardial infarction. Russian Journal of Cardiology. 2015; 4: 59-67. DOI:10.15829/1560-4071-2015-4-59-67. [In Russ.].
4. Дедов И.И., Мельниченко Г.А. Ожирение: этиология, патогенез, клинические аспекты. М.; 2004. Dedov I.I., Mel’nichenko G.A. Ozhirenie: etiologiya, patogenez, klinicheskie aspekty. Mosсow; 2004.
5. Mahabadi A.A., Berg M.H., Lehmann N., Kalsch H., Bauer M., Kara K. et al. Association of epicardial fat with cardiovascular risk factors and incident myocardial infarction in the general population: the Heinz Nixdorf Recall Study. J. Am. Coll. Cardiol. 2013; 61 (13): 1388–1395. DOI:10.1016/j.jacc.2012.11.062.
6. Sacks H.S., Fain J.N. Human epicardial adipose tissue: a review. Am. Heart. J. 2007; 153: 907–917. DOI:10.1016/j.ahj.2007.03.019.
7. Sjoestrom L.A. Сomputed tomography based multicompartment body composition technique and anthropometric predictions of lean body mass, total and subcutaneous adipose tissue. Int. J. Obes. 1991; 15: 19—30.
8. Barbarash O., Gruzdeva O., Uchasova E., Dyleva Y., Belik E., Akbasheva O. et al. The role of adipose tissue and adipokines in the manifestation of type 2 diabetes in the long-term period following myocardial infarction. Diabetol. Metab. Syndr. 2016; 17: 8-24. DOI:10.1186/s13098-016-0136-6.
9. Николаев Д.В., Смирнов А.В., Бобринская И.Г., Руднев С.Г. Биоимпедансный анализ состава тела человека. М.; 2009. Nikolaev D.V., Smirnov A.V., Bobrinskaya I.G., Rudnev S.G. Bioelectric impedance analysis of human body composition. Mosсow; 2009.
10. Чугунова Ю.В., Чумакова Г.А., Веселовская Н.Г. Нейрокогнитивные нарушения у пациентов с висцеральным ожирением в периоперационном периоде коронарного шунтирования. Комплексные проблемы сердечно-сосудистых заболеваний. 2016; 3: 59-65. DOI:10.17802/2306-1278-2016-3-59-65. Chugunova Y.V., Chumakova G.A., Veselovskaya N.G. Neurocognitive disorders among patients with visceral obesity in perioperative period of coronary bypass surgery. Complex Issues of Cardiovascular Diseases. 2016; 3: 59-65. DOI:10.17802/2306-1278-2016-3-59-65. [In Russ.].
11. Aydın A.M., Kayalı A., Poyraz A.K., Aydın K. The relationship between coronary artery disease and pericoronary epicardial adipose tissue thickness. J. Int. Med. Res. 2015; 43 (1): 17-25. DOI:10.1177/0300060514558323.
12. Nalson M.R., Mookadam F., Thota V. Epicardial Fat: An Additional Measurement for Subclinical Atherosclerosis and cardiovascular risk stratification. J. Am. Soc. Echocardioraphy. 2011; 24 (3): 339-345. DOI:10.1016/j.echo.2010.11.008.
13. Драпкина О.М., Корнеева О.Н., Драпкина Ю.С. Эпикардиальный жир: нападающий или запасной? Рациональная фармакотерапия в кардиологии 2013; 9 (3): 287-291. Drapkina O.M., Korneeva O.N., Drapkina Ju.S. Epicardial fat: a striker or a spare? Ration Pharmacother Cardiol 2013; 9 (3): 287-291 [In Russ].
14. Saura D., Oliva M.J., Rodrıguez D., Pascual-Figal D.A., Hurtado J.A., Pinar E. et al. Reproducibility of echocardiographic measurements of epicardial fat thickness. Int. J. Cardiol. 2010; 141: 311–313. DOI:10.1016/j.ijcard.2008.11.127.
15. Sicari R., Sironi A.M., Petz R., Frassi F., Chubuchny V., Daniele de Marchi. et al. Pericardial rather than epicardial fat is a cardiometabolic risk marker: an MRI vs echo study. J. Am. Soc. Echocardiogr. 2011; 24 (10): 1156-1162. DOI:10.1016/j.echo.2011.06.013.
16. Monti M., Monti A., Murlodo G., Renzi P., Pirro M.R., Borgognoni F. et al. Correlation between epicardial fat and cigarette smoking: CT imaging in patients with metabolic syndrome. Scand. Cardiovasc. J. 2014; 48 (5): 317-322.
Review
For citations:
Kokov A.N., Brel N.K., Masenko V.L., Gruzdeva O.V., Karetnikova V.N., Kashtalap V.V., Barbarash O.L. QUANTITATIVE ASSESSMENT OF VISCERAL ADIPOSE DEPOT IN PATIENTS WITH ISCHEMIC HEART DISEASE BY USING OF MODERN TOMOGRAPHIC METHODS. Complex Issues of Cardiovascular Diseases. 2017;(3):113-119. (In Russ.) https://doi.org/10.17802/2306-1278-2017-6-3-113-119
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