AORTITIS - A SILENT DISEASE AND SEVERE COMPLICATIONS
https://doi.org/10.17802/2306-1278-2017-6-4-148-154
Abstract
The article presents a clinical case of delayed diagnosis of extra-articular manifestations of ankylosing spondylitis and aortitis. 15 years after the onset of symptoms, this diagnosis was established when the irreversible joint damage and cardiovascular complications were present, namely extra-articular manufestatations of aortitis, i.e. ascending aortic extension and the total aortic insufficiency. This clinical case presents a successful surgical treatment of acquired aortic valve disease. The patient underwent the Bentall-de Bono procedure, including aortic valve replacement and plasty of the ascending aorta with a valved conduit “MedEng-23” (MedEng, Russia). Moreover, the current article highlights the problem of selecting optimal medical therapy (therapy for ankylosing spondylitis and anticoagulants) due to ad-verse drug interactions. The reasons for delayed diagnosis were analyzed. Unfortunately, the main reasons are subjec-tive, i.e. general physicians (non-rheumatologists) do not know well clinical signs and symptoms of this disease as well as imaging findings suggesting this diagnosis.
About the Authors
N. V. KondrikovaRussian Federation
Kondrikova Natalia.
6, Sosnoviy blvd., Kemerovo, 650002, +7(3842)64-31-53
O. A. Trubnikova
Russian Federation
Kemerovo
A. I. German
Russian Federation
Kemerovo
A. S. Danilovich
Russian Federation
Kemerovo
K. V. Ananeva
Russian Federation
References
1. Сайфутдинов Р.Г., Ахунова P.P., Сибгатулин Т.Б., Семенова О.М. Анкилозирующий спондилит (клинический случай). Дневник казанской медицинской школы. 2015; 1: 58-71. [Sayfutdinov R.G., Akhunova R.R., Sibgatulin T.B., Semenova O.M. Ankylosing spondylitis (clinical case). Kazan medical school diary. 2015; 1: 58-71. (In Russ)]
2. Фоломеева O.M., Галушко E.A., Эрдес Ш.Ф. Распространенность ревматических заболеваний в популяциях взрослого населения России и США. Научно-практическая ревматология. 2008; 46(4): 4-13. [Folomeeva O.M., Galushko E.A., Erdes S.F. Prevalence of rheumatic diseases in adult populations of Russian Federation and USA. Rheumatology Science and Practice. 2008; 46(4): 4-13. doi:10.14412/1995-4484-2008-529. (In Russ)]
3. Кузнецова H.A., Колотова Г.Б. Влияние особенностей' течения заболевания и проводимой'терапии на качество жизни пациентов с анкилозирующим спондилитом. Научно-практическая ревматология. 2015; 53(1): 32-37. [Kuznetsova N.A., Kolotova G.B. Impact of the specific features of disease course and therapy on quality of life in patients with ankylosing spondylitis. Rheumatology Science and Practice. 2015; 53(1): 32-37. doi:10.14412/1995-44842015-32-37. (In Russ)]
4. Roldan C.A., Chavez J., Wiest P.W. Aorticroot disease associated with ankylosing spondylitis. J Am Col Cardiol. 1998; 32(5): 1397-404
5. Lautermann D., Draun J. Ankylosing spondylitis-cardiac manifestations. Clin Exp.Rheumatol. 2002; 20 (Suppl. 28): 511-5.
6. Эрдес Ш.Ф. Основные принципы терапии анкилозирующего спондилита (болезни Бехтерева). Научно-практическая ревматология. 2013; 51(6): 686-95. [Erdes S.F. The basic principles of treatment of ankylosing spondylitis (Bechterew’s disease). Rheumatology Science and Practice. 2013; 51(6): 686-95. doi:10.14412/1995-4484-2013-686-95. (In Russ)]
7. Насонов Е.Л., Насонова B.A. Ревматология: Национальное руководство. М; 2008. [Nasonov E.L., Nasonova V.A. Rheumatology: National guide. M; 2008. (In Russ)]
8. Насонов Е.Л. Ревматология: Клинические рекомендации. М; 2010. [Nasonov E.L. Rheumatology: Clinical guidelines. Moscow; 2010. (In Russ)]
9. Кимова A.M. Современные принципы терапии анкилозирующего спондилоартрита. Русский медицинский журнал. 2015; 25: 1499-1503. [Kimova A.M. Modern principles of treatment of ankylosing spondylitis. Russian Medical Journal. 2015; 25: 1499-1503. (In Russ)]
Review
For citations:
Kondrikova N.V., Trubnikova O.A., German A.I., Danilovich A.S., Ananeva K.V. AORTITIS - A SILENT DISEASE AND SEVERE COMPLICATIONS. Complex Issues of Cardiovascular Diseases. 2017;6(4):148-154. (In Russ.) https://doi.org/10.17802/2306-1278-2017-6-4-148-154