CLINICAL PATTERNS OF VASOSPASTIC ANGINA
https://doi.org/10.17802/2306-1278-2018-7-4-121-127
Abstract
Vasospastic angina (angina inversa, variant angina or Prinzmetal angina) is a rare variant of the course of coronary artery disease. Despite a good understanding of its underlying mechanisms (prolonged coronary spasm resulting from endothelial dysfunction) and contributing factors (smoking, exposure to cold weather, cocaine, autoimmune diseases, etc.), the treatment of each individual patient remains a source of discussion. To date, these patients are commonly treated with drugs, especially calcium antagonists and nitrates. The article presents clinical cases of patients with vasospastic angina and discusses their treatment depending on the individual clinical pattern. Early diagnosis of vasospastic angina allows preventing in some cases fatal complications and save patients’ life.
About the Authors
E. A. UlbashevaRussian Federation
Ulbasheva Elena A., cardiologist at the intensive care wards, Department of Cardiology No. 2
167, 1-st May St., Krasnodar, 350000
A. M. Namitokov
Russian Federation
Namitokov Alim M., PhD, Head of the Department Cardiology No. 2
167, 1-st May St., Krasnodar, 350000
M. V. Kandinsky
Russian Federation
Kandinsky Maxim L., PhD, Head of the Department for Surgical Treatment of Complicated Heart Rhythm Disorders and Cardiac Pacing
167, 1-st May St., Krasnodar, 350000
E. D. Kosmacheva
Russian Federation
Kosmacheva Elena D., PhD, Deputy Director for Clinical Issues
167, 1-st May St., Krasnodar, 350000
References
1. Karpov Ju.A., Bulkina O.S., Lopuhova V.V., Kozlovskaja I.L., Chernova N.A., Bjazrova F.F., Rjabykina G.V., Ljutikova L.N., Polevaja T.Ju., Mironov V.M., Samko A.N. Diagnostika i terapija vazospasticheskoj stenokardii v jepohu invazivnogo lechenija IBS: opisanie klinicheskih sluchaev. RMZh. 2014;23: 1737 (In Russian).
2. Obedinskiy A.A., Bugurov S.V.1, Krestyaninov O.V., Naryshkin I.A., Zubarev D.D., Grazhdankin I.O., Ibragimov R.U., Baystrukov V.I., Naydenov R.A., Kretov E.I. Modern diagnostic capabilities for vasospastic angina diagnostics (intracoronary provocative testing). Patologiya krovoobrashcheniya i kardiokhirurgiya. 2017;21(1):98-103 (In Russian). DOI: 10.21688/1681-3472-2017-1-98-103
3. Takagi Y., Takahashi J., Yasuda S., Miyata S., Tsunoda R., Ogata Y. et al. Prognostic stratifcation of patients with vasospastic angina. JACC 2013;62:1144-1153. DOI: 10.1016/j.jacc.2013.07.018
4. Takagi Y., Yasuda S., Tsunoda R., Ogata Y., Seki A., Sumiyoshi T. et al. Clinical characteristics and long-term prognosis of vasospastic angina patients who survived out-ofhospital cardiac arrest: multicenter registry study of the Japanese Coronary Spasm Association. Circ Arrhythm Electrophysiol 2011;4:295-302. DOI: 10.1161/CIRCEP.110.959809
5. Takatsu F, Watarai M. Mild stenosis makes prognosis of vasospastic angina worse. Coron Artery Dis 2011;22:1-5. DOI: 10.1097/MCA.0b013e3283402313
6. Togashi I., Sato T., Soejima K., Takatsuki S., Miyoshi S., Fukumoto K. et al. Sudden cardiac arrest and syncope triggered by coronary spasm. Inter J Cardiol 2013;163:56-60. DOI: 10.1016/j.ijcard.2011.05.055
7. Sadovnikova I.I. Vazospasticheskaja stenokardija. Nekotorye voprosy terapii. RMZh. 2009;18:1169 (In Russian).
8. D. V. Pevzner, L. O. Dulaev, R. M. Shakhnovich, A. S. Tereshchenko. A case of vasospastic angina with life-threatening heart rhythm. Emergency cardiology. 2016;1:17-23 (In Russian).
9. 2013 ESC guidelines on the management of stable coronary artery disease. The Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur. Heart J. 2013;34:2949-3003. DOI: 10.1093/eurheartj/eht296
10. Walling A., Waters D.D., Miller D.D., Roy D., Pelletier G.B., Theroux P.. Long-term prognosis of patients with variant angina. Circulation. 1987;76(5):990-997.
11. Lupanov V.P. Vazospasticheskaja stenokardija. Spravochnik poliklinicheskogo vracha. 2007;12:15-16 (In Russian).
12. C.Ju. Shtrygol' . Beta-adrenoblokatory: farmakologicheskie svojstva i klinicheskoe primenenie. Provizor. 2003; 13 (In Russian).
13. Korotkevich A.A., Kokov A.N. Hybrid technology of beam diagnostics in the diagnosis of coronary heart disease: current opportunities and prospects. Complex Issues of Cardiovascular Diseases. 2015;(1):5-9 (In Russian). DOI:10.17802/2306-12782015-1-5-9
Review
For citations:
Ulbasheva E.A., Namitokov A.M., Kandinsky M.V., Kosmacheva E.D. CLINICAL PATTERNS OF VASOSPASTIC ANGINA. Complex Issues of Cardiovascular Diseases. 2018;7(4):121-127. (In Russ.) https://doi.org/10.17802/2306-1278-2018-7-4-121-127