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Effects of general anesthesia on systemic inflammatory response during cardiac surgery with extracorporeal circulation

https://doi.org/10.17802/2306-1278-2019-8-4-145-152

Abstract

Systemic inflammatory response syndrome (SIRS) is a severe complication in surgical patients associated with increased morbidity and mortality. Anesthetics are known to produce certain effects on the immune system and the manifestation of SIRS. The understanding of these beneficial mechanisms allows selecting optimal anesthetics in order to reduce the manifestation of SIRS and infectious complications in the postoperative period.

About the Authors

R. R. Adzhigaliev
Federal State Budgetary Institution “Federal Center for Cardiovascular Surgery” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Ruslan R. - anesthesiologist and intensivist at the Intensive Care Unit.

4, Pokrovskaya Roscha St., Astrakhan, 414011; phones +7 (8512) 478-518, +7 (960) 851-25-10


Competing Interests: not


A. E. Bautin
Federal State Budgetary Institution “Almazov National Medical Research Centre” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Bautin Andrei E. - PhD, Head of the Intensive Care Research Laboratory, Associate Professor at the Department of Intensive Care.

2, Akkuratova St., St. Petersburg, 197341


Competing Interests: not


V. V. Pasyuga
Federal State Budgetary Institution “Federal Center for Cardiovascular Surgery” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Pasyuga Vadim V. - PhD, Head of the Intensive Care Unit

4, Pokrovskaya Roscha St., Astrakhan, 414011


Competing Interests: not


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Review

For citations:


Adzhigaliev R.R., Bautin A.E., Pasyuga V.V. Effects of general anesthesia on systemic inflammatory response during cardiac surgery with extracorporeal circulation. Complex Issues of Cardiovascular Diseases. 2019;8(4):145-152. (In Russ.) https://doi.org/10.17802/2306-1278-2019-8-4-145-152

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