PECULIARITIES OF THE COURSE IN STABLE ANGINA ASSOCIATED WITH HYPERTNSION AND TREATMENT ADHERENCE NOVOSIBIRSK CITY RESIDENTS
https://doi.org/10.17802/2306-1278-2014-4-13-18
Abstract
The purpose. To study clinical and angiographic status, N-terminal pro-brain natriuretic peptide (Nt-proBNP) level and treatment adherence in stable angina associated with hypertension patients (pts).
Materials and methods. 151 pts (men) divided into 3 groups were investigated. The 1st group was consisted of 43 men with uncomplicated angina without significant lesions of coronary artery. The 2nd group included 47 men with angina with history of coronary revascularization (percutaneous coronary intervention). The 3rd group included 61 men with angina after previous cardiovascular event (myocardial infarction or stroke).
Results. There were less number of current smokers in uncomplicated stable angina group. 3rd group pts took more alcohol drinks before cardiovascular events. Biochemical blood status were compared in three groups. Structure-functional heart parameters were more disturbed in pts with previous cardiovascular events. Coronary arteries were more lesion in complicated angina pts too. Nt-proBNP levels were significantly higher in patients undergoing cardiovascular events. Factors determining in stable angina associated with hypertension were extent of coronary artery lesion, left-atrium, and left-ventricular size, left-ventricular hypertrophy, and ejection fraction. The relationship between Nt-proBNP levels and left ventricular remodelling as well as between Nt-proBNP levels and extent of coronary arteries lesions were revealed. Adherence to treatment was higher in patients underwent percutaneous coronary intervention.
About the Authors
D. A. Yakhontov
State Budgetary Educational Institution of Higher Professional Education Novosibirsk State Medical University, Novosibirsk
Russian Federation
Russian Federation
E. V. Korosteleva
State Budgetary Educational Institution of Higher Professional Education Novosibirsk State Medical University, Novosibirsk
Russian Federation
Russian Federation
PhD student of hospital therapy and clinical pharmacology departmen
Correspondence address:
E.V. Korosteleva, 52, Krasniy Pr., 630091, Novosibirsk. Tel.: +7 (383) 226-29-71
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Review
For citations:
Yakhontov D.A., Korosteleva E.V. PECULIARITIES OF THE COURSE IN STABLE ANGINA ASSOCIATED WITH HYPERTNSION AND TREATMENT ADHERENCE NOVOSIBIRSK CITY RESIDENTS. Complex Issues of Cardiovascular Diseases. 2014;(4):13-18. (In Russ.) https://doi.org/10.17802/2306-1278-2014-4-13-18
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