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Комплексные проблемы сердечно-сосудистых заболеваний

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Association of cardiovascular biomarkers with myocardial and coronary imaging characteristics in patients having acute myocardial infarction and type 2 diabetes mellitus

https://doi.org/10.17802/2306-1278-2021-10-2S-104-106

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Аннотация

Aim. To assess the dynamic changes and clinical significance of biomarkers of inflammatory processes in patients with acute myocardial infarction (MI) with/ or without type 2 diabetes mellitus (T2DM) and primary percutaneous coronary intervention (pPCI) at various stages of treatment.

Methods. 96 patients with acute MI after pPCI were examined. The level of inflammation markers was measured 4 times: before pPCI (first day from admission to the hospital), on the third day, 7–10 days (before discharge from the hospital) and 40–45 days after pPCI.

Results. All groups of patients with MI showed an increase in the plasma activity of biomarkers of inflammatory processes. After pPCI for 40–45 days, there is a significant difference in the concentration of biomarkers, depending on the comorbid T2DM presence. Strong associations were found between cardiovascular biomarkers and post-MI cardiac remodeling and coronary atherosclerosis progression.

Conclusion. The assessment of the levels of biomarkers of inflammatory processes may have additional clinical value in estimating the course of MI, including patients with T2DM at the postinfarction stages. 

Об авторах

A. S. Vorobev
Surgut State University
Россия

PhD, Associate Professor at the Cardiology Department, 

1, Lenin Ave., Surgut, Khanty-Mansiysk Autonomous Okrug − Yugra, 628412



V. V. Kashtalap
Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»
Россия

MD, Ph.D., Associate Professor, and Head of the Department of Clinical Cardiology, 

6, Sosnoviy Blvd., Kemerovo,650002



I. A. Urvantseva
Surgut State University; District Cardiology Hospital of the Center for Diagnosis and Cardiovascular Surgery
Россия

PhD, Associate Professor, 1, Lenin Ave., Surgut, Khanty-Mansiysk Autonomous Okrug − Yugra, 628412;

Medical Director, 69/1, Lenin Ave., Surgut, Khanty-Mansiysk Autonomous Okrug − Yugra, 628400



K. Yu. Nikolaev
The Institute of Internal and Preventive Medicine, Federal Research Center, Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences
Россия

PhD, Professor, Head of the Laboratory of Urgent therapy, 

175/1, B. Bogatkova St., Novosibirsk, 630089



L. V. Kovalenko
Surgut State University
Россия

PhD, Professor, Director of the Medical Institution, Chairperson of the Department of Pathophysiology
and General Pathology, 

1, Lenin Ave., Surgut, Khanty-Mansiysk Autonomous Okrug − Yugra, 628412



I. D. Astrakhantseva
District Cardiology Hospital of the Center for Diagnosis and Cardiovascular Surgery
Россия

cardiologist, Head of the Department of Department of hospitalization with a telemedicine center,

69/1, Lenin Ave., Surgut, Khanty-Mansiysk Autonomous Okrug − Yugra, 628400



Список литературы

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Для цитирования:


Vorobev A.S., Kashtalap V.V., Urvantseva I.A., Nikolaev K.Y., Kovalenko L.V., Astrakhantseva I.D. Association of cardiovascular biomarkers with myocardial and coronary imaging characteristics in patients having acute myocardial infarction and type 2 diabetes mellitus. Комплексные проблемы сердечно-сосудистых заболеваний. 2021;10(2):104-106. https://doi.org/10.17802/2306-1278-2021-10-2S-104-106

For citation:


Vorobev A.S., Kashtalap V.V., Urvantseva I.A., Nikolaev K.Yu., Kovalenko L.V., Astrakhantseva I.D. Association of cardiovascular biomarkers with myocardial and coronary imaging characteristics in patients having acute myocardial infarction and type 2 diabetes mellitus. Complex Issues of Cardiovascular Diseases. 2021;10(2):104-106. (In Russ.) https://doi.org/10.17802/2306-1278-2021-10-2S-104-106

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ISSN 2306-1278 (Print)
ISSN 2587-9537 (Online)